"Flight by machines heavier than air is unpractical and insignificant, if not utterly impossible."
Simon Newcomb, astronomer ; Said in 1902, less than two years before the first flight at Kitty Hawk
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| Number | Title | Issue Date |
| 7897578 | Peptides with anti-proliferative activity The present invention relates to peptides with anti-proliferative activity, of sequence SEQ ID No. 1, SEQ ID No. 2 or SEQ ID No. 3. ... | 03/01/2011 |
| 7534805 | Imidazole derivatives, their preparation and their use as medicaments Novel imidazole compounds of the formula wherein the substituents are as defined in the application having antitumoral activity and use thereof. ... | 05/19/2009 |
| 7501525 | Derivatives of benzimidazole and their use as medicaments A subject of the present Application is novel derivatives of benzimidazole and imidazo-pyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular the MC4 receptors. They are particularly useful for treating pathological condit... | 03/10/2009 |
| 7501524 | Derivatives of benzimidazole and imidazo-pyridine and their use as medicaments A compound of the formula wherein the substituents are as defined in the specification and pharmaceutical salts thereof having a good affinity for sub-types of melanocortin receptors making them useful for treating diseases... | 03/10/2009 |
| 7495110 | Benzimidazole derivatives and their use as GnRH antagonists A subject of the present application is new benzimidazole derivatives of formula in which A, Y, R1, R2, R3 and R4 represent different variable groups. These products have an antag... | 02/24/2009 |
| 7495021 | Benzothiazole- and benzooxazole-4,7-dione, derivatives and their use as cdc25 phosphate inhibitors The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in ... | 02/24/2009 |
| 7495009 | Imidazopyridine derivatives as melancortin receptor agonists Derivatives of imidazopyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular MC4 receptors and are useful for treating pathological states and diseases in which one or more melanocortin receptors are involved and pharmaceu... | 02/24/2009 |
| 7494969 | Heterocarpine, a plant-derived protein with anti-cancer properties A method of treating cancer dependent on growth factor GHRH in warm-blooded animals in need thereof with an isolated protein extended for Pilocarpus Heterophyllus. ... | 02/24/2009 |
| 7473779 | Derivatives of amidines, their preparation, their use as medicaments and the pharmaceutical compositions containing them Novel derivatives of amidines of formula wherein the substituents are defined as in the specification which are useful for inhibiting activity on NO-synthase enzymes producing nitrogen mono oxide and/or trapping the reactiv... | 01/06/2009 |
| 7465721 | 2-hydroxytetrahydrofuran derivatives and use thereof as medicaments A hydroxytetrahydrofuran of formula wherein A is with the substituents as defined in the specification, having a calpain inhibiting activity and/or an activity which traps the rea... | 12/16/2008 |