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...that when IBM conducted a market study of Chester Carlson's invention in 1959, the company concluded that it would take only 5000 units of his new product to saturate the market? IBM therefore declined to be part of the new product introduction. Too bad for IBM. Carlson's invention was the xerography process, and his new product was the beginning of the Xerox Corporation. It is estimated that every day, worldwide, 3,000,000,000 copies are made!!

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Assignee: SmithKline Beecham plc


Location: GB
No. of patents: 183

1          
NumberTitleIssue Date
7235566Pyridinone derivatives for treatment of atherosclerosis
Compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis. ...
06/26/2007
7232902Process to prepare (1-carboxymethyl)-pyrimidinone compounds
The invention relates to a process for the preparation of certain pyrimidinone compounds. ...
06/19/2007
71538615,6 -Trimethylenepyrimidin-4-one compounds
Pyrimidone compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use is treating atheroscelerosis. ...
12/26/2006
RE39384Substituted thiazolidinedione derivatives
A compound of formula (I): or a tautomeric form thereof, wherein: R1 represents a hydrogen atom, C1-12 alkyl, C1-12 alkoxy, C1-12 alkylcarbonyl or arylC1-12 alky...
11/07/2006
6953803Pyrimidine compounds
Pyrmidinone compounds of formula (I) are inhibitors of the enzyme Lp-PLA2 and of use in therapy, in particular for treating atherosclerosis. ...
10/11/2005
D506545Capsule linker
06/21/2005
D501550Capsule
02/01/2005
D501549Capsule
02/01/2005
6747030Piperazine derivatives as 5-HT1B antagonists
Piperazine derivatives of formula(1), processes for their preparation, pharmaceutical compositions containing them in the treatment of CNS and other disorders and in their use in therapy as 5-HT1B antagonists ...
06/08/2004
6726908Pharmaceutical formulation
This invention relates to pharmaceutical formulations comprising amoxycillin and a salt clavulanic acid in a ratio of 14:1. ...
04/27/2004
6559155Pyrimidinone derivatives for the treatment of atherosclerosis
Pyrimidones of formula (I) are inhibitors of the enzyme LpPLA2 and thereof use in treating inter alia atherosclerosis, ##STR1## in which: R1 is COOH or a salt thereof, COOR10, CONR11R.sup.12, CN or CH...
05/06/2003
6548084Controlled release compositions
A controlled release or delayed release formulation contains a selective serotonin reuptake inhibitor (SSRI) such as paroxetine....
04/15/2003
6521189Combined laboratory condensor and vessel connector
A combined laboratory condenser and vessel connector having a conduit with an inlet/outlet adjacent its upper end with a condenser jacket around the lower part of the conduit, an upper part of the jacket formed into or provided with a connector to enable ...
02/18/2003
6509044Stable, optically clear compositions
A process for preparing an aqueous composition for the preparation of optically clear products, especially beverages, having enhanced stability in syrup and bioavailability for human or animal healthcare. The compositions include an oil soluble ingredient...
01/21/2003
6491874Multi-limbed reaction vessel
A laboratory vessel comprising two substantially cylindrical chambers with parallel longitudinal axes between their bottom and mouth openings and lower and upper conduits linking the chambers so that he contents of the vessel can flow between the first an...
12/10/2002
6489347Process
##STR1## Compounds of structure (1) are obtained by reduction of compounds of the structures ##STR2## ##STR3## Compounds of structure (1), especially where Z is a hydrogen atom or a 3,4-methylenedioxyphenyl group, are important intermediates for inte...
12/03/2002
6482960Process for epoxidizing substituted cyclohexanones
This invention relates to a method for preparing 1-oxaspiro[2,5]-carbonitriles from ketones using spinning disc reactor technology....
11/19/2002
6428808Pharmaceutical composition prepared by addition of a flavor vehicle to a medicament
The invention relates to a method for preparing a flavored liquid medicament, particularly a pediatric preparation in solid form....
08/06/2002
6417192Pyrimidinone compounds and pharmaceutical compositions containing them
A group of novel pyrimidone compounds are inhibitors of the enzyme LDL PLA2 and therefore of use in treating atherosclerosis....
07/09/2002
6410285Alanyl tRNA synthetase from Streptococcus pneumoniae
The invention provides alaS polypeptides and DNA (RNA) encoding alaS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing alaS polypeptides to screen for antibacterial compounds....
06/25/2002
6410286Asparaginyl tRNA synthetase from Staphylococcus Aureus
The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the prote...
06/25/2002
6391891Bicyclic compounds as ligands for 5-HT1 receptors
The invention relates to compounds which are ligands for 5HT1, of formula (I) ##STR1## Wherein L, Q, Ra, Rb and Ry are as defined in the specification, processes for their preparation and their pharmaceutical composit...
05/21/2002
6383473Solid composition for reducing tooth erosion
Acidic oral compositions having reduced tooth erosion characteristics, especially acid beverages such as fruit juice drink concentrates, or oral healthcare products such as mouthwashes, are prepared by adding a calcium compound to the acid composition so ...
05/07/2002
6358528Pharmaceutical formulation
A tablet formulation which comprises a core containing a pharmaceutically active material containing amoxycillin and clavulanate, coated with a release retarding coating, surrounded by a casing layer which includes a second pharmaceutically active materia...
03/19/2002
63589693-desmethylrapamycin or derivatives thereof, processes for their preparation and their use as antifungal agents and immunosuppressants
This invention provides 29-desmethylrapamycin of Formula I: ##STR1## and a pharmaceutical composition thereof....
03/19/2002
6355452Human histamine H3 gene variant-2
Human histamine H3 gene variant-2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Human histamine H3 gene variant-2 polypeptides and polynucleot...
03/12/2002
6348578Apt
The invention provides apt polypeptides and DNA (RNA) encoding apt polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing apt polypeptides to screen for antibacterial compounds....
02/19/2002
6348328Compounds
This invention relates to newly identified polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells tran...
02/19/2002
6346397GyrA
The invention provides gyrA polypeptides and polynucleotides encoding gyrA polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gyrA polypeptides to screen for antibacterial compounds....
02/12/2002
6346392Polynucleotides encoding a novel glutamine transport ATP-binding protein
The invention provides Glutamine Transport ATP-Binding Protein polypeptides and DNA (RNA) encoding Glutamine Transport ATP-Binding Protein polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for ut...
02/12/2002
6345717Reinforced blister pack
A blister pack wherein the material between the blisters is reinforced to confer rigidity relative to flexing deformation of the blister pack. The reinforcement may take the form of a reinforcing slab or sheet, or ribs in the blister pack material. The in...
02/12/2002
6346409Tryptophenyl tRNA synthetase from Streptococcus pneumoniae
The invention provides trpS polypeptides and DNA (RNA) encoding trpS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing trpS polypeptides to screen for antibacterial compounds....
02/12/2002
6344540PAI
The invention provides pai polypeptides and DNA (RNA) encoding pai polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pai polypeptides to screen for antibacterial compounds....
02/05/2002
6335424ribG
The invention provides ribG polypeptides and polynucleotides encoding ribG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ribG polypeptides to screen for antibacterial compounds....
01/01/2002
6316025Swallow tablet comprising paracetamol
The present invention relates to a swallow tablet or capsule formulation comprising paracetamol, sodium bicarbonate, and at least one pharmaceutically acceptable excipient....
11/13/2001
6310193MurC from Streptococcus pneumoniae
The invention provides MurC polypeptides and DNA (RNA) encoding MurC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing MurC polypeptides to screen for antibacterial compounds....
10/30/2001
6310192SigB
SigB polypeptides and DNA (RNA) encoding such SigB and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such SigB for the treatment of infection, particularly bacterial infections...
10/30/2001
6303333SBHWSB2: a new member of the WD40 SOCS box family
SBHWSB2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SBHWSB2 polypeptides and polynucleotides in therapy, and diagnostic assays for such....
10/16/2001
6299903Delayed release pharmaceutical formulation containing a ଲ-lactam antibiotic
Pharmaceutical formulations for oral administration, comprising a matrix which comprises a ଲ-lactam antibiotic, a ଲ-lactamase inhibitor, and granules in a delayed release form dispersed within the matrix which comprise a ଲ-lactam antibio...
10/09/2001
6300097Signal peptidase polypeptides of Staphylococcus aureus
spsB polypeptides and DNA (RNA) encoding such spsB and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spsB for the treatment of infection, particularly bacterial infections...
10/09/2001
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