Quotables
"If you build a better mousetrap, you will catch better mice."
George Gobel
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7270962 | Method of identifying modulators of nogo-functions A method of identifying a modulator Nogo function, the method comprising: (i) providing (a) a BACE polypeptide; (b) a Nogo polypeptide; (c) a test agent | 09/18/2007 |
| 7229640 | Paroxetine controlled release compositions A controlled release or delayed release formulation contains a selective serotonin reuptake inhibitor (SSRI) such as paroxtine. ... | 06/12/2007 |
| 7205408 | Quinolines and nitrogenated derivative thereof substituted in 4-position by a piperidine-containing moiety and their use as antibacterial agents Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man. ... | 04/17/2007 |
| 7199153 | Pharmaceutical composition comprising paracetamol and niflumic acid A formulation is described comprising paracetamol, niflumic acid or a pharmaceutically acceptable salt or ester thereof and a pharmaceutically acceptable excipient. ... | 04/03/2007 |
| 7186730 | Bicyclic nitrogen-containing heterocyclic derivatives for use as antibacterials Piperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man. ... | 03/06/2007 |
| 7169924 | Pyrimidinone derivatives and their use in the treatment of atherosclerosis Compound of formula (I): are disclosed in which: R1 is an aryl group, optionally substituted by 1, 2, 3 or 4 substituents which may be the same or different selected ... | 01/30/2007 |
| 7166608 | -aroyl piperazine derivatives as orexin receptor antagonists This invention relates to N-aroyl piperazine derivatives of formula (I), wherein: Y represents NR2; m represents 1, 2 or 3; p represents 0 or 1; X is O, S, C═O, SO2, or CH═CH—; Ar1 is aryl, or a mono or bicyclic heteroaryl grou... | 01/23/2007 |
| 7163693 | Multi-component pharmaceutical dosage form A multi-component pharmaceutical dosage form comprising a plurality of drug substance-containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected togeth... | 01/16/2007 |
| 7160905 | Hydroxyethylene compounds with Asp2 inhibitory activity The present invention relates to novel hydroxyethylene compounds having Asp2 (β-secretase. BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevat... | 01/09/2007 |
| 7145014 | Process for the preparation of quinoline derivatives The invention relates to a process for the preparation of certain quinoline derivatives, in particular, 8-[(4-amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-(3-trifluoromethylphenoxy)quinoline succinate. ... | 12/05/2006 |
| 7141564 | Nitrogen-containing bicyclic heterocycles for use as antibacterials Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man. ... | 11/28/2006 |
| 7105536 | Compounds The invention relates to novel isoquinolines and their use as anticonvulsants and in the treatment of a variety of disorders. ... | 09/12/2006 |
| 7091359 | Process for the preparation of thiazolidinedione derivatives A process for preparing a compound of formula (I) or a tautomeric form thereof or a pharmaceutically acceptable salt thereof, wherein: A1 represents a substituted or unsubstituted aromatic heterocyclyl group; R1 represents a hydrogen atom, an a... | 08/15/2006 |
| 7078565 | Benzamide derivatives as antagonists of orexin receptors Disclosed are phenyl-alkylene benzamides useful as orexin antagonists ... | 07/18/2006 |
| 7074811 | Hydrochloride salts of 5-[4-[2-(n-methyl-n-(2-pyridyl) amino)ethoxy]benzyl]thiazolidine-2,4-dione A substantially non-hydrated and non-hygroscopic or slightly hygroscopic hydrochloride salt of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione; a pharmaceutical composition containing such a compound, a process of preparing such a compound ... | 07/11/2006 |
| RE39128 | Pleuromutilin derivatives as antimicrobials The present invention relates to pleuromutilin derivatives, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medical therapy, particularly antibacterial therapy. ... | 06/13/2006 |
| 7056654 | Screening assay for inhibitors of human cytochrome P-450 Fluorescein derivative as a substrate for cytochrome P450 enzymes. ... | 06/06/2006 |
| 7045619 | 2-(pyrazol-3-yl)carbapenem derivatives A compound of formula (I): wherein Rα is hydrogen, optionally substituted (C1-6)alkyl or optionally substituted aryl; Rβ is hydrogen, optionally substituted (C | 05/16/2006 |
| 7045626 | Quinoline derivatives, process for preparing them and use for the treatment of diseases mediated by s-CD23 A compound of formula (I): useful in the treatment and prophylaxis of conditions mediated by s-CD23 ... | 05/16/2006 |
| 7045329 | Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme. ... | 05/16/2006 |
| 7026336 | Compounds Compounds of formula (I) wherein X is O, CH2, S or NH, or the moiety X—R1 is hydrogen; V is CH or N; Y is NR10R11, NR10C(Z)NR10R11, NR10COOR11 or NR10SO | 04/11/2006 |
| D516714 | Capsule link | 03/07/2006 |
| 6989447 | Compounds Aminopiperidine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man. ... | 01/24/2006 |
| 6972297 | 2-Hydroxy-mutilin carbamate derivatives for antibacterial use 2-(S)-hydroxymutilin carbamate derivatives of formula (I), in which R1 is a 5- or 6-membered optionally substituted heteroaryl group; and R2 is vinyl or ethyl, are useful in the treatment of bacterial infections | 12/06/2005 |
| 6969526 | Paroxetine controlled release compositions A controlled release or delayed release formulation contains a selective serotonin reuptake inhibitor (SSRI) such as paroxtine. ... | 11/29/2005 |
| 6946130 | Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided. ... | 09/20/2005 |
| 6943160 | Morpholine derivatives as antagonists of orexin receptors This invention relates to morpholine derivatives of formula (I) and their use as antagonists of orexin receptors. ... | 09/13/2005 |
| 6939871 | Benzoxazinone derivatives, their preparation and use The present invention relates to novel compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein Ar is phenyl, naphthyl, a monocyclic heteroaromatic group or a bicyclic heteroaromatic group, said Ar group being optionally substituted by 1-4 sub... | 09/06/2005 |
| 6936458 | Isolated DNA comprising one or more genes specific for 5S clavam biosynthesis, vectors comprising such DNA and streptomyces hosts capable of improved clavulanic acid production Novel bacterial genes, microorganisms and processes for improving the manufacture of 5R clavams, eg. clavulanic acid. ... | 08/30/2005 |
| 6911442 | Quinoline derivatives as antibacterials The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt and/or N-oxide thereof: corresponding novel medicaments, pharmaceutical compositions and/or methods of ... | 06/28/2005 |
| 6908909 | Liquid oral compositions comprising a calcium compound and an acidulant Acidic oral compositions having reduced tooth erosion characteristics, especially acid beverages such as fruit juice drink concentrates, or oral healthcare products such as mouthwashes, are prepared by adding a calcium compound to the acid composition so that the mo... | 06/21/2005 |
| 6905849 | Process for preparing clavam derivatives by using polypeptides having β-lactam synthetase activity The present invention relates to a new process for the synthesis of clavam compounds, in particular clavulanic acid. In one aspect, the invention relates to Streptomyces clavuligerus β-lactam synthetase polypeptide sand Streptomyces clavuligerus β-la... | 06/14/2005 |
| 6900345 | Pleuromutilin derivatives Pleuromutilin compounds of the formula: are of use in anti-bacterial therapy. ... | 05/31/2005 |
| 6878704 | Heterocyclic mutilin esters and their use as antibacterials Pleuromutilin compounds of the formula: are of use in anti-bacterial therapy. ... | 04/12/2005 |
| 6870030 | ASP2 ASP2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ASP2 polypeptides and polynucleotides in the design of protocols for the treatment of Alzheimer's Dise... | 03/22/2005 |
| 6855717 | Tetrahydroisoquinoline derivatives as modulators of dopamine D3 receptors Compounds of formula (I): wherein: R2 represents a hydrogen atom or a C1-4alkyl group; q is 1 or 2; A represents a ... | 02/15/2005 |
| 6849644 | Isoquinoline derivatives useful in the treatment of CNS disorders The invention relates to novel tetrahydroquinoline compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of various CNS disorders. ... | 02/01/2005 |
| 6841560 | Substituted isoquinoline derivatives and their use as anticonvulsants This invention relates to substituted isoquinoline derivatives and their use as anticonvulsants. ... | 01/11/2005 |
| 6838094 | Tablet containing a coated core A tablet formulation which comprises a core containing a pharmaceutically active material, coated with a release retarding coating, surrounded by a casing layer which includes a second pharmaceutically active material. ... | 01/04/2005 |
| 6838255 | MurC The invention provides MurC polypeptides and polynucleotides encoding MurC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing MurC polypeptides to screen for antibacterial compounds. ... | 01/04/2005 |
