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| Number | Title | Issue Date |
| 7220557 | METH1 polynucleotides The present invention relates to novel anti-angiogenic proteins, related to thrombospondin. More specifically, isolated nucleic acid molecules are provided encoding human METH1 and METH2. METH1 and METH2 polypeptides are also provided, as are vectors, host cells and... | 05/22/2007 |
| 7067280 | Human cartilage glycoprotein Nucleic acid sequences for HC gp-39L are provided. Methods of detecting altered expression of tissue remodeling proteins and diagnosing tissue remodeling disorders are also provided. ... | 06/27/2006 |
| 7052862 | Lipoprotein associated phospholipase A, inhibitors thereof and use of the same in diagnosis and therapy The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compunds to identify those compounds. ... | 05/30/2006 |
| 6936688 | Human chemokine beta-10 mutant polypeptides Human chemokine Beta-10 polypeptides and DNA (RNA) encoding such chemokine polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such chemokine polypeptides for the treatment of ... | 08/30/2005 |
| 6391589 | Human chemokine beta-10 mutant polypeptides Human chemokine Beta-10 polypeptides and DNA (RNA) encoding such chemokine polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such chemokine polypeptides for the tr... | 05/21/2002 |
| 6224832 | Multi-reactor synthesizer and method for combinatorial chemistry Solid phase combinatorial synthesis is carried out in a multi-reactor synthesizer comprising an array of separate reactor cells (1-9) containing a solid reaction support medium (26). Subsets of the reactor cells (1-9) are interconnected with one another i... | 05/01/2001 |
| 5968818 | Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibi... | 10/19/1999 |
| 5942402 | Method of detecting and treating cancer The present invention provides a new method for diagnosing and treating cancers or BPH. Further provided are therapeutic agents and pharmaceutical compositions for treating cancers and BPH.... | 08/24/1999 |
| 5869295 | Methods and materials for producing gene libraries Methods for producing libraries of diverse nucleotide sequences, and libraries of polypeptides encoded thereby, are provided. The nucleotide sequences comprise a first and a second constant region coupled to a coding sequence, wherein the coding sequence ... | 02/09/1999 |
| 5795893 | Fibrinogen receptor antagonists This invention relates to novel compounds which inhibit platelet aggregation, pharmaceutical compositions containing the compounds, and methods of using the compounds.... | 08/18/1998 |
| 5792431 | Multi-reactor synthesizer and method for combinatorial chemistry Solid phase combinatorial synthesis is carried out in a multi-reactor synthesizer comprising an array of separate reactor cells containing a solid reaction support medium. Subsets of reactor cells are interconnected with one another in a desired pattern, ... | 08/11/1998 |
| 5747264 | Method of diagnosing and monitoring prostate cancer The present invention provides a new method for diagnosing and treating cancers or BPH. Further provided are therapeutic agents and pharmaceutical compositions for treating cancers and BPH.... | 05/05/1998 |
| 5726061 | Method of diagnosing and monitoring colorectal cancer Methods of screening for colorectal cancer by measuring levels of HC gp-39 are provided. Methods of monitoring patients with colorectal cancer are also provided. In addition, kits for detection of HC gp-39 useful in screening for and monitoring of colorec... | 03/10/1998 |
| 5656467 | Methods and materials for producing gene libraries Methods for producing libraries of diverse nucleotide sequences, and libraries of polypeptides encoded thereby, are provided. The nucleotide sequences comprise a first and a second constant region coupled to a coding sequence, wherein the coding sequence ... | 08/12/1997 |
| 5641877 | 17- and 17-ଲ substituted acyl-3-carboxy-3, 5-dienes and use in inhibiting 5--reductase Invented are 17 and 17ଲ-substituted acyl-3-carboxy-3,5-diene analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5--reductase. Als... | 06/24/1997 |
| 5641765 | 17-댚nd 17-ଲsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5--reductase Invented are 17 and 17ଲ-substituted acyl-3-carboxy-3,5-diene analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5--reductase. Als... | 06/24/1997 |
| 5639748 | 6,9-disubstituted benzazepines having -adrenoceptor blocking activity Alpha-adrenergic receptor antagonists having the formula: ##STR1## which are useful to produce -adrenoceptor antagonism, pharmaceutical compositions including these antagonists, and methods of using these antagonists to produce -adrenoc... | 06/17/1997 |
| 5637310 | Method of treating prostatic adenocarcinoma Invented is a Method of Treating Prostatic Adenocarcinoma by employing asteroid 5--reductase inhibiting compound or a combination of steroid 5--reductase inhibiting compounds.... | 06/10/1997 |
| 5362915 | Phenyl-substituted cycloalkenyl compounds useful as PDE IV inhibitors A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein: R1 is --CH3 or --CH2 CH3 unsubstituted or substituted by 1 to 3 fluorines; X is O or S(O)s where s=0 to 2; R | 11/08/1994 |
| 5279939 | Protein protease inhibitors from streptomyces This invention relates to novel protein protease inhibitors as well as DNAs encoding same and vectors and transformed host cells useful for the recombinant production of the inhibitors.... | 01/18/1994 |
| 5206143 | Method and reagents for performing subset analysis using quantitative differences in fluorescence intensity Methods for distinguishing multiple subpopulations of biological particles in a single sample based upon quantitative differences in the fluorescence intensity attributable to one or two fluorochromes with which the biological particles are labelled. The ... | 04/27/1993 |
| 5089271 | Stabilized antibiotic compositions for animal feeding Stabilized antibiotic composition for animal feeds which provide for improved recovery of the antibiotic from the animal feed. The compositions contain the antibiotic in a coated form. In a preferred embodiment the antibiotic is coated by microencapsulati... | 02/18/1992 |
