...that it was melting ice cream that inspired the invention of the outboard motor? It was a lovely August day and Ole Evinrude was rowing his boat to his favorite island picnic spot. As he rowed, he watched his ice cream melt and wished he had a faster way to get to the island. At that moment the idea for the outboard motor was born!
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| Number | Title | Issue Date |
| 7919091 | Lipolysis stimulated receptor (LSR) specific antibodies The present invention relates to antibodies specific for a receptor termed the Lipolysis Stimulated Receptor (LSR). Compositions comprising the antibodies are also provided. ... | 04/05/2011 |
| 7910329 | genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia trachomatis, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication p... | 03/22/2011 |
| 7838241 | Genotyping methods using genomic sequence of the 5-lipoxygenase-activating protein (FLAP) and polymorphic markers thereof The invention concerns the genomic sequence of the FLAP gene. The invention also concerns biallelic markers of a FLAP gene and the association established between these markers and diseases involving the leukotriene pathway such as asthma. The invention provides mea... | 11/23/2010 |
| 7671024 | OBG3 globular head and uses thereof The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. The application is related to OBG3 polypepide fragments and compositions comprising these fragments. It also discloses methods of reduc... | 03/02/2010 |
| 7601531 | polynucleotides and uses thereof The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia pneumoniae, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication pr... | 10/13/2009 |
| 7575913 | Chlamydia trachomatis genomic sequence and polypeptides, fragments thereof and uses thereof, in particular for the diagnosis, prevention and treatment of infection The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia trachomatis, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication p... | 08/18/2009 |
| 7547771 | Polymorphic markers of prostate carcinoma tumor antigen -1(PCTA-1) The invention concerns the geNo.mic sequence and cDNA sequences of the PCTA-1 gene. The invention also concerns biallelic markers of the PCTA-1 gene and the association established between these markers and prostate cancer. The invention provides means to determine ... | 06/16/2009 |
| 7494777 | Genomic sequence of the 5-lipoxygenase-activating protein (FLAP), polymorphic markers thereof and methods for detection of asthma The invention concerns the genomic sequence of the FLAP gene. The invention also concerns biallelic markers of a FLAP gene and the association established between these markers and diseases involving the leukotriene pathway such as asthma. The invention provides mea... | 02/24/2009 |
| 7459433 | Homotrimeric extended OBG3 globular head and uses thereof The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. A compound, homotrimer of OBG3 polypeptide fragment comprising globular domain and all or part of OBG3 collagen-like region, has been i... | 12/02/2008 |
| 7449543 | Schizophrenia related protein The invention relates to polynucleotides of the PAPAP gene, polypeptides encoded by the PAPAP gene, and antibodies directed specifically against such polypeptides. The invention also concerns methods for the treatment or diagnosis of schizophrenia, bipolar disorder ... | 11/11/2008 |
| 7449304 | Method for enhancing the efficiency of an enzymatic process for removal of contaminating nucleotides This invention relates to methods for enhancing the efficiency of biological processes that involve successive enzymatic reactions. More specifically, the invention relates to methods for enhancing the efficiency of an enzymatic purification process by increasing th... | 11/11/2008 |
| 7442519 | KCNQ2-15 potassium channel The invention encompasses polypeptides and polynucleotides of three novel bipolar disorder-associated potassium channel polypeptides, KCNQ2-15bx, KCNQ2-15by and KCNQ2-15bz. The invention further relates to the use of potassium channels comprising KCNQ2 subunits for ... | 10/28/2008 |
| 7432367 | Nucleic acid encoding a retinoblastoma binding protein (RBP-7) and polymorphic markers associated with said nucleic acid The present invention is directed to a polynucleotide comprising open reading frames defining a coding region encoding a retinoblastoma binding protein (RBP-7) as well as regulatory regions located both at the 5′ end and the 3′ end of said coding region. The pre... | 10/07/2008 |
| 7432056 | Biallelic markers derived from genomic regions carrying genes involved in arachidonic acid metabolism The invention provides polynucleotides including biallelic markers derived from genes involved in arachidonic acid metabolism and from genomic regions flanking those genes. Primers hybridizing to regions flanking these biallelic markers are also provided. This inven... | 10/07/2008 |
| 7427482 | Methods of assessing the risk for the development of sporadic prostate cancer The invention concerns the genomic sequence of the purH gene. The invention also concerns biallelic markers of a purH gene and the association established between these markers and cancer, particularly prostate cancer. The invention provides means to determine the p... | 09/23/2008 |
| 7413875 | ESTs and encoded human proteins The sequences of 5′ ESTs and consensus contigated 5′ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5′ ESTs and consensus contigated 5′ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5′ ESTs and consensus contigated ... | 08/19/2008 |
| 7405193 | Use of Acrp30 globular head to promote increases in muscle mass and muscle differentiation The present invention relates to the field of muscle research, in particular to the discovery of a compound effective for increasing muscle mass, muscle cell differentiation, and oxidation of free fatty acids in muscle, useful in methods of treating muscle-related d... | 07/29/2008 |
| 7402393 | Methods of screening for antagonists of APM1/GZIP The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GZIP polypeptides have been identified that are believed to be beneficial in the treatment of metaboli... | 07/22/2008 |
| 7393663 | Expressed sequence tags and encoded human proteins The sequences of 5′ ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5′ ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5′ ESTs. The 5′ ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping... | 07/01/2008 |
| 7393661 | Nucleic acids encoding OBG3 polypeptides The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. This application pertains to nucleic acids encoding a compound, globular OBG3 polypeptide fragments, vectors and transformed host cells... | 07/01/2008 |
| 7385034 | Complementary DNAs encoding proteins with signal peptides The sequences of cDNAs encoding secreted proteins are disclosed. The cDNAs can be used to express secreted proteins or fragments thereof or to obtain antibodies capable of specifically binding to the secreted proteins. The cDNAs may also be used in diagnostic, foren... | 06/10/2008 |
| 7371811 | Schizophrenia associated genes, proteins and biallelic markers The invention concerns the human sbg1, g34665, sbg2, g35017 and g35018 genes, polynucleotides, polypeptides biallelic markers, and human chromosome 13q31-q33 biallelic markers. The invention also concerns the association established between schizophrenia and bipolar... | 05/13/2008 |
| 7358066 | Variants and exons of the GlyT1 transporter The present invention provides polypeptide and polynucleotide sequences for novel splice variants of the sodium and chloride-dependent glycine transporter type 1 (GlyT1). These polypeptides and polynucleotides are useful in the treatment and diagnosis of disorders s... | 04/15/2008 |
| 7348406 | Metabolic gene polynucleotides and polypeptides and uses thereof The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GMG-3, GMG-4, Cluster 1, GMG-6A, or GMG-6B polypeptides have been identified that are beneficial in th... | 03/25/2008 |
| 7344843 | Agonists and antagonists of prolixin for the treatment of metabolic disorders The present invention relates to the field of metabolic research, in particular the discovery of compounds effective for reducing body mass and useful for treating obesity-related diseases and disorders. The obesity-related diseases or disorders envisioned to be tre... | 03/18/2008 |
| 7338787 | Nucleic acids encoding OBG3 globular head and uses thereof The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. A compound, globular OBG3, has been identified that reduces weight gain in animals. This compound should be effective for reducing body... | 03/04/2008 |
| 7326678 | GMG-3 GMG-4 and GMG-6 polynucleotides and polypeptides and uses thereof The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GMG-3, GMG-4, Cluster 1, GMG-6A, or GMG-6B polypeptides have been identified that are beneficial in th... | 02/05/2008 |
| 7291709 | LSR receptor, its activity, its cloning, and its applications to the diagnosis, prevention and/or treatment of obesity and related risks or complications The present invention relates to a new complex receptor polypeptide LSR (Lipolysis Stimulated Receptor), characterized by its functional activities, the cloning of the cDNAs complementary to the messenger RNAs encoding each of the subunits of the multimeric complex,... | 11/06/2007 |
| 7291495 | β-Secretase variant The invention provides polynucleotides and polypeptides encoding an isolated amyloid inhibitor protein (APIP) and compositions thereof. The polypeptides of the subject invention can be used to inhibit the catabolism or sequential cleavage of amyloid beta precursor p... | 11/06/2007 |
| 7285631 | Human cDNAs and proteins and uses thereof The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be use... | 10/23/2007 |
| 7276342 | Xobesin agonists and antagonists for the treatment of metabolic disorders The present invention relates to the field of metabolic research, in particular the discovery of compounds effective for reducing body mass and useful for treating obesity-related diseases and disorders. The obesity-related diseases or disorders envisioned to be tre... | 10/02/2007 |
| 7271243 | Full-length human cDNAs encoding potentially secreted proteins The invention concerns GENSET polynucleotides and polypeptides. Such GENSET products may be used as reagents in forensic analyses, as chromosome markers, as tissue/cell/organelle-specific markers, in the production of expression vectors. In addition, they may be use... | 09/18/2007 |
| 7235381 | Expressed sequence tags and encoded human proteins The sequences of 5′ ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5′ ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5′ ESTs. The 5′ ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping... | 06/26/2007 |
| 7223727 | GSSP4 polynucleotides and polypeptides and uses thereof The present invention relates to the field of metabolic research. Metabolic disorders, such as obesity, are a public health problem that is serious and widespread. GSSP4 polypeptides have been identified that are believed to be beneficial in the treatment of metabol... | 05/29/2007 |
| 7220722 | Lipoprotein-regulating medicants Methods and pharmaceutical compositions useful for treating obesity-related disorders using ApM-1 and related proteins. ... | 05/22/2007 |
| 7220581 | Schizophrenia related gene The invention relates to polynucleotides of the PAPAP gene, polypeptides encoded by the PAPAP gene, and antibodies directed specifically against such polypeptides. The invention also concerns methods for the treatment or diagnosis of schizophrenia, bipolar disorder ... | 05/22/2007 |
| 7189833 | Prostate cancer gene The present invention relates to PG1, a gene associated with prostate cancer. The invention provides polynucleotides including biallelic markers derived from PG1 and from flanking genomic regions. Primers hybridizing to these biallelic markers and regions flanking a... | 03/13/2007 |
| 7125667 | Polymorphic markers of the LSR gene The invention provides novel LSR genomic sequences, polypeptides, antibodies, and polynucleotides including biallelic markers derived from the LSR locus. Primers hybridizing to regions flanking these biallelic markers are also provided. This invention also provides ... | 10/24/2006 |
| 7122644 | Methods and compositions for inhibiting neoplastic cell growth The invention provides the genomic sequence of GSSP-2, GSSP-2 cDNAs and GSSP-2 polypeptides. Further the invention provides polynucleotides including biallelic markers derived from the GSSP-2 gene and from genomic regions flanking the gene. This invention also provi... | 10/17/2006 |
| 7118869 | Genomic sequence of the 5-Lipoxygenase-activating protein (FLAP), polymorphic markers thereof and methods for detection of asthma The invention concerns the genomic sequence of the FLAP gene. The invention also concerns biallelic markers of a FLAP gene and the association established between these markers and diseases involving the leukotriene pathway such as asthma. The invention provides mea... | 10/10/2006 |