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| Number | Title | Issue Date |
| 6541211 | Apparatus and method for synthesizing combinational libraries An apparatus and method for synthesizing a combinatorial library comprising a plurality of chemical compounds such that the chemical composition of each compound is easily tracked. The library compounds are synthesized on solid-phase supports, which are s... | 04/01/2003 |
| 6127190 | Method for producing combinatorial libraries having a predetermined frequency of each species of test compound A technique is disclosed for generating nonrandom combinatorial libraries on solid phase supports in which each of a set of predetermined species of test compounds is present on a predetermined number of solid phase supports, preferably on only one, and e... | 10/03/2000 |
| 6090912 | Topologically segregated, encoded solid phase libraries comprising linkers having an enzymatically susceptible bond The invention relates to libraries of synthetic test compound attached to separate phase synthesis supports. In particular, the invention relates to libraries of synthetic test compound attached to separate phase synthesis supports that also contain codin... | 07/18/2000 |
| 5849510 | Factor Xa inhibitors The invention provides compounds which specifically inhibit factor Xa activity. The compounds consist of the structure X1 -YIR-X2, wherein X1 is H, acyl, alkyl, acylalkyl, arylalkyl or one or more amino acids, and X2 | 12/15/1998 |
| 5846841 | Motif Libraries The invention concerns libraries of chemical compounds, that are useful in medicinal chemistry and related arts, their methods of manufacture and methods of their use. In one embodiment the individual chemical species of the library are synthesized aleato... | 12/08/1998 |
| 5688696 | Combinatorial libraries having a predetermined frequency of each species of test compound A technique for generating nonrandom combinatorial libraries on solid phase supports in which each of a set of predetermined species of test compounds is present on a predetermined number of solid phase supports, preferably on only one, and each solid pha... | 11/18/1997 |
| 5635598 | Selectively cleavabe linners based on iminodiacetic acid esters for solid phase peptide synthesis The present invention is directed to linkers based on ester bond linkages, especially iminodiacetic acid ester bond linkages, for use in solid phase peptide synthesis. In particular, the invention is directed to cleavable linkers that can release peptide ... | 06/03/1997 |
| 5470753 | Peptide sequencing using mass spectrometry The present invention relates to methods for determining the amino acid composition, and more preferably the sequence, of a peptide using mass spectrometric techniques. The method is particularly useful for sequencing peptides isolated from natural source... | 11/28/1995 |
