"What can be more palpably absurd than the prospect held out of locomotives traveling twice as fast as stagecoaches?"
The Quarterly Review ; March edition, 1825
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| Number | Title | Issue Date |
| 5041606 | Process for the O-alkylation of N-(hydroxy)aralkylphenylethanolamines A process for the preparation of a compound of formula ##STR1## wherein X represents hydrogen, halogen, trifluoromethyl or lower alkyl group; W represents methyl, Q represents hydrogen or W and Q, together, form an ethylene group and R' represents a ... | 08/20/1991 |
| 4846184 | Skin reflectance measuring apparatus A probe comprising a casing of which one face which will be in contact with the skin is providied with an aperture, is connected to a measuring device by means of a flexible connection in fiber optics comprising at least three optical conductors which, at... | 07/11/1989 |
| 4847265 | Dextro-rotatory enantiomer of methyl alpha-5 (4,5,6,7-tetrahydro (3,2-c) thieno pyridyl) (2-chlorophenyl)-acetate and the pharmaceutical compositions containing it The present invention relates to the dextro-rotatory enantiomer of Formula ##STR1## and its pharmaceutically acceptable salts with platelet aggregation inhibiting activity. The invention also relates to a process for the preparation of this compound ... | 07/11/1989 |
| 4816598 | 4-Amino-butanoic acid derivatives The invention relates to 4-amino-butanoic acid derivatives of general formula: ##STR1## in which: M represents an alkali metal atom, R represents a protected amino group, R1 represents a labile group, R2 represents hydrogen, a branch... | 03/28/1989 |
| 4814485 | 4-aminobutanoic acid derivatives, process of preparation and use thereof The invention relates to new (4S)-4-aminobutanoic acid derivatives of general formula: ##STR1## in which: R represents an N-protective group, R1 represents hydrogen, an alkali metal atom such as lithium, sodium or potassium or a liabile gr... | 03/21/1989 |
| 4791102 | Derivatives of the N -arylsulphonylaminoacyl-p-amidinophenylalaninamides, their preparation process, their use as medicaments and the pharmaceutical compositions containing them The present invention is concerned with compounds with the formula: ##STR1## in which: R1 represents a lower alkyl, a lower hydroxy alkyl or a benzyl group, a phenyl group or a 4-hydroxy phenyl group: R2 and R3, identical ... | 12/13/1988 |
| 4749566 | Pharmaceutical composition comprising a combination of at least one immunotoxin and at least one mannose-containing polymer The invention relates to pharmaceutical compositions comprising a combination of at least one immunotoxin and at least one mannose-containing polymer. This combination makes it possible to inhibit the rapid elimination of immunotoxins from the plasma afte... | 06/07/1988 |
| 4739072 | Process for preparing tetrahydrocarbazolones The invention relates to a process for the preparation of a compound of general formula (I) ##STR1## wherein R1 represents a hydrogen atom or a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-(C1-4... | 04/19/1988 |
| 4739065 | Intermediates for anti-bacterial thienopyridinones Thienopyridinone derivatives of the general formula: ##STR1## in which Y represents hydrogen or a lower alkyl group and X represents: a hydroxy, lower alkanoyloxy, lower alkoxy unsubstituted or substituted by a hydroxy, lower alkoxy, di-(lower alkyl)... | 04/19/1988 |
| 4735947 | Methyllevallorphanium salts having peripheral opiate antagonistic activity Methyllevallorphanium salts having peripheral antagonistic activity of formula ##STR1## wherein Yn(-) represents the anion a pharmaceutically acceptable acid other than halogen and n represents the number of negative charges of said a... | 04/05/1988 |
| 4725580 | Peptide derivatives, analogous to pepstatin, which inhibit renin and acid proteases The invention relates to pepstatin analogs which inhibit renin and acid proteases. These analogs are particularly suitable for the treatment of arterial tension.... | 02/16/1988 |
| 4721711 | Pyridazine derivatives active on the central nervous system, and medicaments in which they are present The invention relates to the pyridazine derivatives of the formula: ##STR1## in which R1 is H, a substituted or unsubstituted phenyl group, a naphthyl group, a cyclohexyl group, a thien-2-yl group, a thien-3-yl group or an indol-3-yl group... | 01/26/1988 |
| 4721710 | Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity, and pharmaceutical compositions The present invention relates to derivatives of piperidinedione of formula: ##STR1## in which R is alkyl or forms with N a possibly substituted morpholino or piperidino group, n=2 or 3, R1, R2, R3 and R4 re... | 01/26/1988 |
| 4720581 | Benzamidine derivatives The present invention relates to benzamidine derivatives corresponding to the general formula ##STR1## in which: A represents a linear or branched alkyl chain containing from 3 to 9 carbon atoms; and X represents the oxygen atom or a direct bond, wit... | 01/19/1988 |
| 4687760 | Reduced peptides which inhibit gastric secretion, process for their preparation and pharmaceutical compositions in which they are present The invention relates to the peptides of the formula: ##STR1## in which: R1 represents hydrogen or a protecting group for the amine group, such as t-butoxycarbonyl, benzyloxycarbonyl or lower alkanoyl groups; X represents beta-alanine glyc... | 08/18/1987 |
| 4677106 | Derivatives of 4-methyl 6-phenyl pyridazine, active on the central nervous system The present invention relates to derivatives of 4-methyl 6-phenyl pyridazine of formula: ##STR1## in which R is OH or H, R1 is H or ##STR2## n being 0 or 1, X being H, Y being H or alkyl or X and Y forms an ethylene or oxoethyle... | 06/30/1987 |
| 4576946 | Derivatives of 4-methyl 6-phenyl pyridazine active on the central nervous system The present invention relates to derivatives of 4-methyl 6-phenyl pyridazine of formula: ##STR1## in which R is OH or H, R1 is H or ##STR2## n being 0 or 1, X being H, Y being H or alkyl or X and Y forms an ethylene or oxoethylen... | 03/18/1986 |
| 4499092 | Derivatives of 4-phenyl quinazoline active on the central nervous system The present invention relates to novel derivatives of 4-phenyl quinazoline of general formula: ##STR1## in which R2 is H or halogen or R1 is a hydroxyamino derivative of type ##STR2## in which at least R3 or... | 02/12/1985 |
| 4409228 | Andrexiant aminopiperidines intermediates thereto and drugs containing same The present invention relates to novel 4-amino-1-(2-pyridyl)piperidines with anorexiant action, of formula: ##STR1## in which R represents hydrogen, a halogen, a methyl group, a trifluoromethyl group, a lower alkoxy group, a trifluoromethoxy group, a... | 10/11/1983 |