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Assignee: Sandia National Laboratories


Location: Livermore, CA
No. of patents: 111

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NumberTitleIssue Date
7437766Method and apparatus providing deception and/or altered operation in an information system operating system
A method and/or system and/or apparatus providing deception and/or execution alteration in an information system. In specific embodiments, deceptions and/or protections are provided by intercepting and/or modifying operation of one or more system calls of an operati...
10/14/2008
7368290Structural determination of intact proteins using mass spectrometry
The present invention relates to novel methods of determining the sequence and structure of proteins. Specifically, the present invention allows for the analysis of intact proteins within a mass spectrometer. Therefore, preparatory separations need not be performed ...
05/06/2008
7311882Capillary interconnect device
A manifold for connecting external capillaries to the inlet and/or outlet ports of a microfluidic device for high pressure applications is provided. The fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate that includes: (i)...
12/25/2007
7310142Fast time-correlated multi-element photon detector and method
Photons emitted from a sample responsive to being excited by laser pulses are directed through a prism onto a photomultiplier tube having several spaced-apart anodes. The prism alters the path of each photon as a function of its wavelength so that the wavelength det...
12/18/2007
7308374Method for siting detectors within a facility
A method, system and article of manufacture of siting one or more detectors in a facility represented with zones are provided. Signals Si,j representing an effect in zone j in response to a release of contaminant in zone i for one or more flow conditions ...
12/11/2007
7296274Method and apparatus providing deception and/or altered execution of logic in an information system
A method and/or system and/or apparatus providing deception and/or execution alteration in an information system. In specific embodiments, deceptions and/or protections are provided by intercepting and/or modifying operation of one or more system calls of an operati...
11/13/2007
7256667Waveguide device and method for making same
A monolithic micromachined waveguide device or devices with low-loss, high-power handling, and near-optical frequency ranges is set forth. The waveguide and integrated devices are capable of transmitting near-optical frequencies due to optical-quality sidewall rough...
08/14/2007
7225683Composition pulse time-of-flight mass flow sensor
A device for measuring fluid flow rates over a wide range of flow rates (10 μL/min) and at pressures at least as great as 2,000 psi. The invention is particularly adapted for use in microfluidic systems. The device operates by producing compositional ...
06/05/2007
7213473Sample preparation system for microfluidic applications
An apparatus that couples automated injection with flow feedback to provide nanoliter accuracy in controlling microliter volumes. The apparatus comprises generally a source of hydraulic fluid pressure, a fluid isolator joined to the outlet of the hydraulic pressure ...
05/08/2007
7204923Continuous flow dielectrophoretic particle concentrator
A continuous-flow filter/concentrator for separating and/or concentrating particles in a fluid is disclosed. The filter is a three-port device an inlet port, an filter port and a concentrate port. The filter separates particles into two streams by the ratio of their...
04/17/2007
7186987Organic materials and devices for detecting ionizing radiation
A π-conjugated organic material for detecting ionizing radiation, and particularly for detecting low energy fission neutrons. The π-conjugated materials comprise a class of organic materials whose members are intrinsic semiconducting materials. Included in this cl...
03/06/2007
7182371Edge compression manifold apparatus
A manifold for connecting external capillaries to the inlet and/or outlet ports of a microfluidic device for high pressure applications is provided. The fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate that includes: (i)...
02/27/2007
7162864Method for control of NOx emission from combustors using fuel dilution
A method of controlling NOx emission from combustors. The method involves the controlled addition of a diluent such as nitrogen or water vapor, to a base fuel to reduce the flame temperature, thereby reducing NOx production. At the same time, a gas capable of enhanc...
01/16/2007
7161334Modular high voltage power supply for chemical analysis
A high voltage power supply for use in a system such as a microfluidics system, uses a DC—DC converter in parallel with a voltage-controlled resistor. A feedback circuit provides a control signal for the DC—DC converter and voltage-controlled resistor so as to r...
01/09/2007
7151787Backscatter absorption gas imaging systems and light sources therefore
The location of gases that are not visible to the unaided human eye can be determined using tuned light sources that spectroscopically probe the gases and cameras that can provide images corresponding to the absorption of the gases. The present invention is a light ...
12/19/2006
7128559Programmable imprint lithography template
A template for imprint lithography (IL) that reduces significantly template production costs by allowing the same template to be re-used for several technology generations. The template is composed of an array of spaced-apart moveable and individually addressable ro...
10/31/2006
7128046Fuel mixture stratification as a method for improving homogeneous charge compression ignition engine operation
A method for slowing the heat-release rate in homogeneous charge compression ignition (“HCCI”) engines that allows operation without excessive knock at higher engine loads than are possible with conventional HCCI. This method comprises injecting a fuel charge in...
10/31/2006
7124994Silicon micro-mold
The present invention describes a method for rapidly fabricating a robust 3-dimensional silicon-mold for use in preparing complex metal micro-components. The process begins by depositing a conductive metal layer onto one surface of a silicon wafer. A thin photoresis...
10/24/2006
7094326Electrodes for microfluidic applications
An electrode device for high pressure applications. These electrodes, designed to withstand pressure of greater than 10,000 psi, are adapted for use in microfluidic devices that employ electrokinetic or electrophoretic flow. The electrode is composed, generally, of ...
08/22/2006
7090189Compliant cantilevered micromold
A compliant cantilevered three-dimensional micromold is provided. The compliant cantilevered micromold is suitable for use in the replication of cantilevered microparts and greatly simplifies the replication of such cantilevered parts. The compliant cantilevered mic...
08/15/2006
7071595Translation and rotation positioning motor
A positioning device provides the capability of moving an object in both a linear and a rotational direction. The positioning device includes a first piezo stack with plural piezo plates that are capable of movement in orthogonal directions with respect to each othe...
07/04/2006
7051956Ejector device for direct injection fuel jet
Disclosed is a device for increasing entrainment and mixing in an air/fuel zone of a direct fuel injection system. The device comprises an ejector nozzle in the form of an inverted funnel whose central axis is aligned along the central axis of a fuel injector jet an...
05/30/2006
7052608Cast-to-shape electrokinetic trapping medium
A three-dimensional microporous polymer network material, or monolith, cast-to-shape in a microchannel. The polymer monolith, produced by a phase separation process, is capable of trapping and retaining charged protein species from a mixture of charged and uncharged...
05/30/2006
7030355Low power photomultiplier tube circuit and method therefor
An electrical circuit for a photomultiplier tube (PMT) is disclosed that reduces power consumption to a point where the PMT may be powered for extended periods with a battery. More specifically, the invention concerns a PMT circuit comprising a low leakage switch an...
04/18/2006
7027150Apparatus for measuring the concentration of a species at a distance
Corrosion of refractory silica brick and air quality issues due to particulate emissions are two important glass manufacturing issues that have been tied to sodium vapor and its transport throughout the melt tank. Knowledge of the relationship between tank operating...
04/11/2006
7022861Thermally cleavable surfactants
Two new surfactant molecules are reported which contain thermally labile Diels-Alder adducts connecting the polar and non-polar sections of each molecule. The two surfactants possess identical non-polar dodecyl tail segments but exhibit different polar headgroups. T...
04/04/2006
7022381Method for producing high dielectric strength microvalves
A microvalve having a cast-in-place and lithographically shaped mobile, polymer monolith for fluid flow control in microfluidic devices and method of manufacture. The microvalve contains a porous fluorinated polymer monolithic element whose pores are filled with an ...
04/04/2006
7022287Single particle electrochemical sensors and methods of utilization
The present invention discloses an electrochemical device for detecting single particles, and methods for using such a device to achieve high sensitivity for detecting particles such as bacteria, viruses, aggregates, immuno-complexes, molecules, or ionic species. Th...
04/04/2006
7019637Systems and methods for detecting and processing
Embodiments of the present invention provides systems and method for detecting. Sensing modules are provided in communication with one or more detectors. In some embodiments, detectors are provided that are sensitive to chemical, biological, or radiological agents. ...
03/28/2006
7012342Low power, scalable multichannel high voltage controller
A low voltage control circuit is provided for individually controlling high voltage power provided over bus lines to a multitude of interconnected loads. An example of a load is a drive for capillary channels in a microfluidic system. Control is distributed from a c...
03/14/2006
7008737Gray scale x-ray mask
The present invention describes a method for fabricating an embossing tool or an x-ray mask tool, providing microstructures that smoothly vary in height from point-to-point in etched substrates, i.e., structure which can vary in all three dimensions. The process use...
03/07/2006
7005301Piecewise uniform conduction-like flow channels and method therefor
A low-dispersion methodology for designing microfabricated conduction channels for on-chip electrokinetic-based systems is presented. The technique relies on trigonometric relations that apply for ideal electrokinetic flows, allowing faceted channels to be designed ...
02/28/2006
7001535Polymer formulation for removing hydrogen and liquid water from an enclosed space
This invention describes a solution to the particular problem of liquid water formation in hydrogen getters exposed to quantities of oxygen. Water formation is usually desired because the recombination reaction removes hydrogen without affecting gettering capacity a...
02/21/2006
7001849Surface treatment and protection method for cadmium zinc telluride crystals
A method for treatment of the surface of a CdZnTe (CZT) crystal that provides a native dielectric coating to reduce surface leakage currents and thereby, improve the resolution of instruments incorporating detectors using CZT crystals. A two step process is disclose...
02/21/2006
6998598Modular optical detector system
A modular optical detector system. The detector system is designed to detect the presence of molecules or molecular species by inducing fluorescence with exciting radiation and detecting the emitted fluorescence. Because the system is capable of accurately detecting...
02/14/2006
6994826Method and apparatus for controlling cross contamination of microfluid channels
A method for controlling fluid flow at junctions in microchannel systems. Control of fluid flow is accomplished generally by providing increased resistance to electric-field and pressure-driven flow in the form of regions of reduced effective cross-sectional area wi...
02/07/2006
6988402Mobile monolithic polymer elements for flow control in microfluidic devices
A cast-in-place and lithographically shaped mobile, monolithic polymer element for fluid flow control in microfluidic devices and method of manufacture. Microfluid flow control devices, or microvalves that provide for control of fluid or ionic current flow can be ma...
01/24/2006
6975402Tunable light source for use in photoacoustic spectrometers
The present invention provides a photoacoustic spectrometer that is field portable and capable of speciating complex organic molecules in the gas phase. The spectrometer has a tunable light source that has the ability to resolve the fine structure of these molecules...
12/13/2005
6969576Photosensitive dissolution inhibitors and resists based on onium salt carboxylates
A photoresist composition that employs onium salt carboxylates as thermally stable dissolution inhibitors. The photoresist composition can be either an onium carboxylate salt with a phenolic photoresist, such as novolac, or an onium cation protected carboxylate-cont...
11/29/2005
6966336Fluid injection microvalve
A microvalve for extracting small volume samples into analytical devices, e.g., high pressure liquid chromatography (HPLC) column, includes: a first body having a first interior surface and two or more outlet ports at the first interior surface that are in fluid com...
11/22/2005
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