...During the Civil War, the Confederacy established its own Patent Office which issued 266 patents, a third of which concerned implements of war.
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| Number | Title | Issue Date |
| 8105581 | Compositions and methods for inducing neuronal differentiation The present invention provides compositions and methods for inducing neuronal cell differentiation. ... | 01/31/2012 |
| 8097422 | Kir channel modulators Provided is a three-dimensional structure of an alcohol bound to an alcohol-binding site of an inwardly rectifying potassium (Kir) channel, Kir channel alcohol modulators and methods for identifying Kir channel modulators. ... | 01/17/2012 |
| 8092992 | Transcriptional regulation of gene expression by small double-stranded modulatory RNA The invention provides a method for modulating gene expression by contacting a cellular system with a double-stranded ribonucleic acid molecule capable of associating with a regulatory machinery that controls transcription of one or more genes, wherein the associati... | 01/10/2012 |
| 7674455 | Targeted retrograde gene delivery to motor neurons Methods are disclosed for delivering a heterologous gene to a cell body of a neuron by contacting a muscle tissue innervated by the neuron with a viral vector comprising a heterologous gene, wherein the viral vector enters said neuron and is retrogradely moved to th... | 03/09/2010 |
| 7643226 | Maximal-aperture reflecting objective Objectives and other optical assemblies include a reflective surface that is truncated at or near a focus based on a curvature of the reflective surface. A specimen is situated at or near the focus of the reflective surface, so that the reflective surface captures a... | 01/05/2010 |
| 6974671 | Methods for indentifying compounds that modulate gluconeogenesis through the binding of CREB to the PGC-1 promoter In accordance with the present invention, it has been discovered that CREB regulates hepatic gluconeogenesis via the co-activator, PGC-1. PGC-1 potentiated glucocorticoid induction of the gene for PEPCK, the rate limiting enzyme in gluconeogenesis, via the glucocort... | 12/13/2005 |