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| Number | Title | Issue Date |
| 6174900 | Substituted piperidine derivative for treating urinary disturbance Disclosed herein is a substituted piperidine derivative represented by the following general formula (1): ##STR1## wherein R1 means an aryl or heteroaryl group which may have at least one substituent, R2 denotes an alkyl, alkenyl or ... | 01/16/2001 |
| 6171520 | Reagents for labeling SH groups, process for the preparation of them and method for labeling with them Disclosed are SH-labeling reagents containing acridine compounds represented by the following formula (I): ##STR1## wherein A represents the following group: --(CH2)m1 -- or --(CH2)m2 --Q--(CH2)n | 01/09/2001 |
| 6103538 | Colloidal gold immunoassay method Disclosed herein is a method for the detection of a target substance by a colloidal gold immunoassay, which comprises dissolving in an immunoreaction system a metal salt selected from the group consisting of sodium, potassium and lithium fluorides, sodium... | 08/15/2000 |
| 6063945 | Triazole derivative or salt thereof A compound having formula (2): ##STR1## wherein R represents hydrogen, a straight or branched C1-10 alkyl group, a C7-11 aralkyl group or a C2-10 carboacyl group and m stands for 1 to 5.... | 05/16/2000 |
| 6046218 | Pyridine derivative and medicament containing the same as an effective ingredient Described is a pyridine derivative represented by the following formula (1): ##STR1## wherein R1 and R2 individually represent H, an alkyl group, a cycloalkyl group, a hydroxyalkyl group, an alkoxyalkyl group which may have... | 04/04/2000 |
| 6002028 | Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) ... | 12/14/1999 |
| 5986144 | Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) ... | 11/16/1999 |
| 5968956 | Substituted piperidine derivative and medicine comprising the same Disclosed herein is a substituted piperidine derivative represented by the following general formula (1): ##STR1## wherein R1 means an aryl or heteroaryl group which may have at least one substituent, R2 denotes an alkyl, alkeny... | 10/19/1999 |
| 5945438 | Triazole derivative and pharmaceutical comprising the same as an effective ingredient Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) ... | 08/31/1999 |
| 5939448 | Triazole derivative or salt thereof Described is a triazole derivative represented by the formula (1): wherein R represents a hydrogen atom, an alkyl group, an aralkyl group or an acyl group, n stands for 0 to 2 and m stands for 1 to 5 or salt thereof, and a pharmaceutical containing the de... | 08/17/1999 |
| 5935977 | Substituted vinyl pyridine derivative and drugs containing the same The present invention relates to a substituted vinylpyridine derivative represented by the following formula (1): ##STR1## (wherein R1 represents a hydrogen atom, an alkyl group, etc., R2 represents an alkyl group; one of R... | 08/10/1999 |
| 5922767 | Substituted benzylurea derivatives and medicine containing the same Disclosed herein are substituted benzylurea derivatives represented by the following general formula (1): ##STR1## wherein R1 and R2 are independently H, a halogen atom, or an alkyl or alkoxyl group, R3 is a phenyl or... | 07/13/1999 |
| 5902826 | Platinum (IV) complex and pharmaceutical composition comprising the same A diamine-platinum (IV) complex represented by the following formula (1): ##STR1## wherein R1 and R2 together represent R5 O--CH(CH2 NH2)2 (R5 represents hydrogen, acetyl, triflu... | 05/11/1999 |
| 5866609 | Substituted vinylurea derivatives and medicine containing the same Disclosed herein are substituted vinylurea derivatives represented by the following general formula (1): ##STR1## wherein R1 and R3 are independently a phenyl group which may be substituted, R2 is a phenyl group which... | 02/02/1999 |
| 5789419 | 4-quinolinone derivative or salt thereof This invention relates to a 4-quinolinone derivative represented by the following general formula (1): ##STR1## wherein R1 and R2 mean individually H, halogen, cyano, or lower alkyl, lower alkylsulfonyl, lower alkylsulfinyl, low... | 08/04/1998 |
| 5710152 | Benzoazine derivative or salt thereof and pharmaceutical compostion comprising the same A benzoazine derivative represented by the following formula (1), ##STR1## wherein R1 represents an alkyl group, alkoxy group, halogen atom, halogenoalkyl group, amino group, hydroxy group, benzyloxy group which may have a substituent, cya... | 01/20/1998 |
| 5707878 | Method for detecting blood component using conidiobolus hemagglutinin A method for detecting blood component in a sample comprising reacting a human erythrocyte membrane band 3 glycoprotein (band 3) in the sample and a hemagglutinin produced by a microorganism belonging to the genus Conidiobolus (CA) and measuring said band... | 01/13/1998 |
| 5676970 | Anti-inflammatory analgesic plaster An anti-inflammatory analgesic plaster carries thereon a base which comprises piroxicam and a polyoxyethylene nonionic surfactant having 5-15 moles of added ethylene oxide.... | 10/14/1997 |
| 5654002 | Piroxicam tablets and production and process thereof A process is provided for the production of piroxicam tablets. According to the process, a solution of a water-soluble high-molecular substance is added to a mixture of piroxicam and lactose. The resultant mixture is granulated and then compressed into ta... | 08/05/1997 |
| 5585511 | Platinum complex and malignant tumor treating drug containing the same A platinum complex represented by the following formula (1): ##STR1## wherein the all symbols are defined in the disclosure; and a malignant tumor treating drug which contains the complex as an active ingredient. The platinum complex is excellent in ... | 12/17/1996 |
| 5578600 | Stable liquid preparation of complex vitamin for internal use Described is a stable liquid preparation of complex vitamin for internal use. The preparation containing vitamin B1 and vitamin B12, and as a sweetening agent, a sugar alcohol. The pH of the preparation has been adjusted to 3.5 to 4.... | 11/26/1996 |
| 5532371 | Piperazine substituted carboxylic acid derivatives for treating hyperlipimia An arylamide derivative of formula (1), a salt thereof and a therapeutic agent for hyperlipemia which comprises the derivative or salt: ##STR1## wherein Ar represents a group ##STR2## a naphthyl group, a pyridinyl group, a furyl group, a thienyl... | 07/02/1996 |
| 5500221 | Sustained release suppository The present invention relates to a sustained-release suppository preparation characterized by comprising an acidic drug or a salt thereof which can be absorbed by rectal administration and an acidic compound or a pH buffering agent. The sustained-release ... | 03/19/1996 |
| 5498780 | Platinum complex and malignant tumor treating drug containing the same A diamine-platinum complex represented by the following formula (1): ##STR1## wherein the all definitions are defined in the disclosure, and a malignant tumor treating drug which contains the above complex as an active ingredient. The diamine-platinu... | 03/12/1996 |
| 5496561 | Controlled release-initiation and controlled release-rate pharmaceutical composition A controlled release-initiation and controlled release-rate pharmaceutical composition in which a drug-containing composition is coated with a membrane layer comprising a water insoluble high polymer and silicone. The starting time for the release of drug... | 03/05/1996 |
| 5496819 | Antiphlogistic-analgesic plaster comprising triacetin and piroxicam An antiphlogistic-analgesic plaster comprising piroxicam and triacetin and/or triethyl citrate. The antiphlogistic-analgesic plaster of the invention is excellent in percutaneous absorption of piroxicam and hence has an excellent antiphlogistic and analge... | 03/05/1996 |
| 5447926 | Quinolone carboxylic acid derivatives A quinolone carboxylic acid derivative having the following formula (1), ##STR1## wherein R1 is a hydrogen atom, an alkyl group, an aralkyl group, an ester residual group which can be hydrolyzed in living bodies, R2 is a hydroge... | 09/05/1995 |
| 5440036 | 1,4-benzoxazine derivatives A 1,4-benzoxazine derivative represented by the following formula (1): ##STR1## wherein R1 represents an unsubstituted or halogen-substituted lower alkyl, unsubstituted or halogen-substituted lower alkylsulfonyl, nitro or cyano group, R | 08/08/1995 |
| 5430028 | 5-aminoquinolone carboxylic acid derivative and antibacterial agent containing the same as active ingredient A 5-aminoquinolone carboxylic acid derivative represented by the following general formula (1): ##STR1## wherein R1 means a hydrogen atom, an amino group, a linear or branched alkyl group having 1-5 carbon atoms and an alkylamino group ... | 07/04/1995 |
| 5422102 | Antiinflammatory and analgesic gel preparation An antiinflammatory and analgesic gel preparation comprising diclofenac or its salts, an ester of dibasic acid, a lower alcohol, and a nonionic polymer or a mixture of nonionic polymers selected from the group consisting of (a) 1.5-4% by weight of hydroxy... | 06/06/1995 |
| 5411972 | Arylamide derivatives for treating hyperlipemia An arylamide derivative of formula (1), a salt thereof and a therapeutic agent for hyperlipemia which comprises the derivative or salt: ##STR1## wherein Ar represents a group ##STR2## a naphthyl group, a pyridinyl group, a furyl group, a thienyl... | 05/02/1995 |
| 5405840 | Pranoprofen-containing, suspending medicinal composition A pranoprofen-containing, suspending medicinal composition is formed of the following three ingredients (a) to (c): (a) pranoprofen; (b) a suspending agent comprising microcrystalline cellulose-sodium carboxymethylcellulose, sodium carboxymethylcellulose and h... | 04/11/1995 |
| 5385900 | Quinoline carboxylic acid derivatives A quinolone carboxylic acid derivative having the following formula (1), ##STR1## wherein R1 is a hydrogen atom, an alkyl group, an aralkyl group, an ester residual group which can be hydrolyzed in living bodies, R2 is a hydroge... | 01/31/1995 |
| 5350769 | Antiinflammatory gel preparation The present invention relates to an antiinflammatory gel preparation comprising an ammonium or sodium salt of diclofenac, a nonionic polymer, a dibasic ester, and a lower alcohol. The gel preparation of the present invention exhibits superior percutaneous... | 09/27/1994 |
| 5348744 | Antidiarrheal compositions containing loperamide hydrochloride and a saccharide Described herein are antidiarrheal compositions containing loperamide hydrochloride as an effective ingredient and a saccharide, for example, a monosaccharide, oligosaccharide or sugar alcohol in an amount as much as at least 3,000 times the weight of lop... | 09/20/1994 |
| 5324735 | Quinoline carboxylic acid derivatives The present invention relates to a quinolone carboxylic acid derivative represented by the following the formula (I), ##STR1## wherein R1 is a lower alkyl group, R2 is a hydrogen atom or a lower alkyl group, R3 is a h... | 06/28/1994 |
| 5300517 | Piperidine compounds having anti-acetylcholinesterase activity Piperidine compounds of formula II: ##STR1## that exhibit anticholinesterase activity and are effective in treating dementia.... | 04/05/1994 |
| 5275825 | Compressed-molded preparations Compressed molded preparations are disclosed. In the preparation coated granules of a pharmaceutical composition are compressed and molded together with non-coated component(s) containing 10% or more by weight of non-swelling polymers. According to the pr... | 01/04/1994 |
| 5258375 | Composition for the preparation of dosage-form active vitamins D3 containing polyvinylacetal diethylaminoacetate Compositions suitable for use in the preparation of dosage-form active vitamins D3 are disclosed. Each composition comprises an active vitamin D3 and a stabilizer selected from polyvinylacetal diethylaminoacetate and hydroxypropylcel... | 11/02/1993 |
| 5240934 | Quinoline derivatives Quinoline derivatives of the formula, ##STR1## wherein >A represents a group >N--(CH2)n --, >C.dbd., >C.dbd.CH(CH2)n --, or >CH(CH2)n --, wherein n is an integer of 0-7; Y represents a... | 08/31/1993 |
