Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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| Number | Title | Issue Date |
| 4746676 | Carboxyalkyl dipeptide compounds Compounds having the general structure ##STR1## and their pharmaceutically acceptable salts, wherein the substituents are defined herein, which exhibit antihypertensive activity.... | 05/24/1988 |
| 4744986 | Process for the preparation of a viscosity-stable antacid composition A process for the preparation of a viscosity-stable antacid composition containing an alginic acid salt comprising reacting an antacid material with said salt at elevated temperatures to form a reaction product and recovering said reaction product in stab... | 05/17/1988 |
| 4745110 | Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of... | 05/17/1988 |
| 4745131 | Amidinoureas for treating irritable bowel syndrome 1-Phenyl-3N-alkyl amidinoureas are useful in the treatment of Irritable Bowel Syndrome.... | 05/17/1988 |
| 4743608 | Pyridone-pyridyl-imidazolyl and triazolyl compounds and their use as cardiotonic agents This invention relates to pyridone-pyridyl-imidazolyl and triazolyl compounds, including methods for increasing cardiac contractility, pharmaceutical compositions including the same and methods for the preparation thereof.... | 05/10/1988 |
| 4743600 | Benzocyclobutene aminoalkylene ethers and thioethers, pharmaceutical compositions and use A class of benzocyclobutene aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of g... | 05/10/1988 |
| 4742055 | 3- and 5-amino thiatriazines, and their pharmaceutical uses A class of 3- and 5-amino thiatriazine compounds exhibiting pharmacological activity, including anti-ulcerogenic and gastrointestinal cytoprotective activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastroi... | 05/03/1988 |
| 4734434 | Method for the treatment of pruritus and composition for the use therein A method for the relief of pruritus comprising the administration of an effective antipruritic amount of a N-(trifluoromethylphenyl)anthranilic acid ester to an afflicted patient.... | 03/29/1988 |
| 4727169 | 3- and 5-(bicyclic ether or bicyclic alkylene thioether) alkylene amino thiatriazines, and their pharmaceutical uses A class of 3- and 5-amino thiatriazine compounds exhibiting pharmacological activity, including gastrointestinal anti-ulcerogenic and cytoprotective activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastroi... | 02/23/1988 |
| 4722925 | Bicyclic benzo-oxy heterocyclic ethers and thioethers pharmaceutical compositions and use A class of bicyclic benzo-oxy heterocyclic ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of ... | 02/02/1988 |
| 4721721 | 6-(4-thiazole) compounds, cardiotonic compositions including the same, and their uses Cardiotonic fused aromatic bicyclic ring substituted thiazole compounds and their salts, methods for increasing cardiac contractility in humans and other mammals by the use of said compounds, pharmaceutical compositions including said compounds and method... | 01/26/1988 |
| 4714707 | Aryl substituted heterocycles for treating gastrointestinal motility dysfunction Aryl substituted diazaheterocyclic amines and their use in the treatment of gastrointestinal motility dysfunctions.... | 12/22/1987 |
| 4707478 | Heterocyclic amidino substituted ureas and their pharmaceutical uses This invention relates to methods for the prophylactic and curative treatment of gastrointestinal and cardiovascular disorders and parasitic infections in humans and animals, using a class of hetrocyclic amidino substituted urea and thiourea compounds, a ... | 11/17/1987 |
| 4704401 | Substituted phenyl amidinoureas This invention relates to a method of lowering blood pressure in humans and mammals using 2,6-disubstituted phenyl amidinoureas in which the phenyl ring is additionally substituted by a hydroxy, alkoxy, aralkoxy, alkenyloxy, alkynyloxy, haloacyloxy, or ac... | 11/03/1987 |
| 4704388 | 3- And 5-(bicyclic ether or bicyclic alkylene thioether)alkylene amino thiatriazines, and their pharmaceutical uses A class of 3- and 5-amino thiatriazine compounds exhibiting pharmacological activity, including gastrointestinal anti-ulcerogenic and cytoprotective activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastroi... | 11/03/1987 |
| 4703037 | Angiotensin-converting enzyme inhibitors Compounds of the formula ##STR1## and their pharmaceutically acceptable salts, wherein the substituents are as defined herein, having antihypertensive activity.... | 10/27/1987 |
| 4701457 | Amidinoureas for treating irritable bowel syndrome Amidinoureas are disclosed as useful for the treatment of irritable bowel syndrome.... | 10/20/1987 |
| 4699906 | Bicyclic benzenoid alkylene amino thieno[3,4-d]isothiazole ethers and thioethers, pharmaceutical compositions and use A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of... | 10/13/1987 |
| 4693059 | Mandrel for opening a tube of flexible material A mandrel for opening a tube of flexible banding material wherein the tube is delivered in flat ribbon-like form with creased side edges is disclosed. The mandrel is in the form of a tetrahedron with two sets of surfaces which are in the form of isosceles... | 09/15/1987 |
| 4692445 | Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of... | 09/08/1987 |
| 4677210 | 1-arylalkoxy- and 1-arylalkylthioaryl-2-pyrazolines as anti-inflammatory or anti-allergic agents Z is a chemical bond or an alkylene chain containing up to 5 carbons in the principal chain and up to a total of 7 carbons; X is O or S; R and R1 are independently hydrogen, hydroxy, lower alkoxy, lower alkanoyloxy, halo, cyano, carboloweralkoxy, ca... | 06/30/1987 |