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| Number | Title | Issue Date |
| 6846660 | Method of making an aldehyde dehydrogenase with gluconobacter A new aldehyde dehydrogenase having the physico-chemical properties: molecular weight:150,000±6,000 or 230,000±9,000; substrate specificity active on aldehyde compounds; cofactors:pyrroloquinoline quinone and heme c; optimum pH: 7.0-8.5; and inhibitors: Co2+ | 01/25/2005 |
| 6844470 | Process for the purification of 1,3-diketones A process for the purification of 1,3-diketones comprising reacting a 1,3-diketone with an earth metal or alkaline earth metal complexing agent in an organic solvent, isolating, washing and decomposing the resulting complex, and isolating the purified 1,3-diketone. | 01/18/2005 |
| 6784207 | Phytanic acid derivative compositions The present invention is a method for the treatment or prevention of preferably non-insulin dependent (NIDDM or so-called Type II) diabetes mellitus, or other conditions associated with impaired glucose tolerance such as obesity, and in particular to the use of phyt... | 08/31/2004 |
| 6777212 | Microbial process for producing L-ascorbic acid, D-erythorbic acid, and salts thereof A process for producing L-ascorbic acid or D-erythorbic acid, or in each case its sodium, potassium or calcium salt, from 2-keto-L-gulonic acid or 2-keto-D-gluconic acid, or in each case its sodium, potassium or calcium salt, that involves incubating 2-keto-L-guloni... | 08/17/2004 |
| 6743615 | Process for the manufacture of a vitamin E intermediate The present invention is a process for converting trimethylhydroquinone diacetate (TMHQ-DA) into trimethylhydroquinone-1-monoacetate (TMHQ-1-MA) by contacting TMHQ-DA with a lipase to effect an enzymatic monosaponification of the TMHQ-DA. Also provided are methods o... | 06/01/2004 |
| 6737256 | Overcoming DAPA aminotransferase bottlenecks in biotin vitamers biosynthesis A method is disclosed for the increased production of biotin and the biotin precursor dethiobiotin using a bacterium that produces a lysine-utilizing DAPA aminotransferase. This method involves the use of a bacterium that is either grown in the presence of lysine or... | 05/18/2004 |
| 6734004 | Modified phytases A process for the production of a modified phytase with a desired property improved over the property of the corresponding unmodified phytase is disclosed, as well as modified phytases, polynucleotides encoding modified phytases, and animal feed including modified p... | 05/11/2004 |
| 6730503 | Alcohol/aldehyde dehydrogenase The present invention is directed to a recombinant enzymes having alcohol and aldehyde dehydrogenase activity which comprises one or mom recombinant polypeptides selected from the group consisting of polypeptides which are identified by SEQ ID NO 5, SEQ ID NO 6, SEQ... | 05/04/2004 |
| 6722780 | Preparation of liquid dispersions A process for mixing or dispersing liquids is provided that includes introducing liquids to be mixed or dispersed into a mixing device having a cylindrical support. The cylindrical support includes an inlet nozzle having a bore which is in fluid communication throug... | 04/20/2004 |
| 6723346 | Process for preparing spray granules containing riboflavin The invention is concerned with a novel process for the manufacture of flowable, non-dusty, binder-free riboflavin granulates by subjecting an aqueous suspension of riboflavin crystals of crystal modification B/C to a fluidized bed spray drying process, a single flu... | 04/20/2004 |
| 6723544 | Biotin biosynthetic genes The present invention relates to the production process of biotin by fermentation using a genetically engineered microorganism, and DNA sequences and vectors to be used in such process. ... | 04/20/2004 |
| 6720174 | Phytases This invention relates to improved phytases, preferably phytases of an increased thermostability, and a process of producing them. In particular, stabilizing amino acid mutations are introduced into a homologous protein, or the active site of a phytase is replaced i... | 04/13/2004 |
| 6700002 | Process for making vitamin E using hydrogen-tris(oxalato) phosphate A process for the manufacture of (all-rac)--tocopherol by the catalyzed reaction of trimethylhydroquinone with isophytol or phytol is characterized by carrying out the reaction in the presence of hydrogen tris(oxalato)phosphate, or an adduct thereo... | 03/02/2004 |
| 6699704 | Heat tolerant phytases The present invention relates to heat tolerant phytases and DNA sequences which code therefor. The phytases are useful in hydrolyzing phytate to inositol and inorganic phosphates. The phytases are valuable feed additives.... | 03/02/2004 |
| 6696293 | Process for producing carotenoids and biological materials useful therefor A process for producing carotenoids, which involves cultivating a microorganism obtained by treating a parent microorganism that produces carotenoids under conditions that induce a reduction in alternative oxidase activity and selecting a microorganism wi... | 02/24/2004 |
| 6677134 | Fermentative carotenoid production Novel proteins of microorganism E-396 (FERM BP-4283) and the DNA sequences which encode these proteins have been discovered to provide an improved biosynthetic pathway from farnesyl pyrophosphate and isopentyl pyrophosphate to various carotenoids, especia... | 01/13/2004 |
| 6673583 | Recombinantly producing levodione reductase The present invention is directed to genetic material useful for the preparation of actinol, such as an isolated DNA including a nucleotide sequence coding for an enzyme having levodione reductase activity, a polypeptide encoded by such a DNA, recombinant... | 01/06/2004 |
| 6664082 | Genetically engineered L-sorbose reductase-deficient mutants The present invention provides a genetically engineered microorganism belonging to the genus Gluconobacter or Acetobacter, which has an engineered gene for the biological activity of reducing L-sorbose which is more than 90% non-functional in developing t... | 12/16/2003 |
| 6656721 | Polynucleotide portions of the biotin operon from B. subtilis for use in enhanced fermentation The present invention provides a process for producing a target fermentation product. This process includes providing a fermentation medium containing a recombinantly-produced microorganism that over-produces a fermentation product and contains a mutation... | 12/02/2003 |
| 6651898 | Method and device for atomizing liquids The present invention is a device for atomizing liquids which has: a) a rotatable apparatus for the reception of liquids to be atomized, the apparatus is defined by a cylinder having an interior chamber that runs the length of the cylinder with an internal... | 11/25/2003 |
| 6653115 | D-sorbitol dehydrogenase gene Polynucleotides encoding proteins with D-sorbitol dehydrogenase activity or which function to activate D-sorbitol dehydrogenase proteins, in vivo, vectors and recombinant organisms which contain such polynucleotides, and methods of making D-sorbitol dehyd... | 11/25/2003 |
| 6646135 | Continuous process for the enantioselective hydrogenation of alpha ketocarbonyl compounds The invention relates to a continuous process for enantioselective catalytic hydrogenation of an alpha ketocarbonyl compound such as alpha ketoesters and alpha ketolactones to produce an alpha hydroxy carbonyl compound.... | 11/11/2003 |
| 6623774 | Preparation and stabilization of food-grade marine oils The present invention relates to stabilizing marine oil by treatment with silica in the presence or absence of carbon and vacuum steam deodorization at a temperature between about 140° C. and about 210° C. in the presence of 0.1-0.4% deodorized rosemary... | 09/23/2003 |
| 6613543 | Fermentative carotenoid production Novel proteins of Flavobacterium sp. R1534 and the DNA sequences which encode these proteins are disclosed which provide an improved biosynthetic pathway from farnesyl pyrophosphate and isopentyl pyrophosphate to various carotenoid precursors and caroteno... | 09/02/2003 |
| 6599735 | Continuous fermentation system A fermentation assembly comprising: (a) a vessel for culturing living cells; (b) at least two storage flasks in fluid communication with the vessel for supply of liquids and a first transport means for transferring the liquids from the storage flasks to t... | 07/29/2003 |
| 6586202 | Isoprenoid production The present invention relates to an isolated DNA sequence encoding an enzyme in the mevalonate pathway or the pathway from isopentenyl pyrophosphate to farnesyl pyrophosphate. Vectors and plasmids including such DNA are also set forth. The invention also ... | 07/01/2003 |
| 6579975 | Consensus phytases A process for obtaining a consensus protein from a group of amino acid sequences of a defined protein family, proteins and polynucleotides so obtained, and compositions containing such proteins.... | 06/17/2003 |
| 6573269 | Pyrimidine-2,4,6-trione light screening compositions The present invention provides compounds of formula I, which are effective in absorbing ultraviolet radiation and can be used as sunscreen agents: ##STR1## wherein R1 and R2 are each independently C2 -C18 alkyl, C | 06/03/2003 |
| 6551813 | Nutrient medium for bacterial strains which overproduce riboflavin Vectors and recombinant bacteria for overproducing riboflavin, in which nucleic acid overproducing riboflavin biosynthetic proteins is introduced in the chromosome of the host organism, e.g. at multiple sites and in multiple copies per site. A rib operon ... | 04/22/2003 |
| 6536940 | Preparation of liquid dispersions A process for mixing or dispersing liquids is provided that includes introducing liquids to be mixed or dispersed into a mixing device having a cylindrical support. The cylindrical support includes an inlet nozzle having a bore which is in fluid communica... | 03/25/2003 |
| 6534297 | Recombinantly producing levodione reductase The present invention is directed to genetic material useful for the preparation of actinol, such as an isolated DNA including a nucleotide sequence coding for an enzyme having levodione reductase activity, a polypeptide encoded by such a DNA, recombinant... | 03/18/2003 |
| 6530684 | Preparation of liquid dispersions A process for mixing or dispersing liquids is provided that includes introducing liquids to be mixed or dispersed into a mixing device having a cylindrical support. The cylindrical support includes an inlet nozzle having a bore which is in fluid communica... | 03/11/2003 |
| 6528025 | Process of manufacturing equipment for preparing acetals and ketals A process for the preparation of acetals and ketals by reacting an aldehyde or Ketone with an alcohol in the presence of solid acid and removing water by pervaporation. Manufacturing equipment for the preparation of acetals and ketones is also provided.... | 03/04/2003 |
| 6521564 | Modification of a hydrogenation catalyst A process for the modification of a hydrogenation catalyst of the Raney nickel, Raney cobalt, nickel-on-carrier or cobalt-on-carrier type, which process includes treating the hydrogenation catalyst at temperatures of about 0° C. to about 120° C. with ca... | 02/18/2003 |
| 6489486 | 2-hydroxyphenyl benzotriazoles as UV-A/B filters The present invention relates to a process for the manufacture of compounds of Formula (I): ##STR1## wherein R1 is alkyl; R2, R3, R4, R5 and R6 are, independently, hydrogen, alkyl or alkeny... | 12/03/2002 |
| 6482961 | Method of making (all-rac)--tocopherol The present invention is a method of making (all-rac)--tocopherol in a reaction having the following steps: a) reacting trimethylhydroquinone and a phytol selected from the group consisting of isophytol and phytol in the presence of a bis(perfluorinated... | 11/19/2002 |
| 6465228 | Levodione reductase A levodione reductase having the following physical properties is provided: molecular weight: from about 142,000 to about 155,000&#b1;10,000 (consisting of four homologous subunits having a molecular weight of 36,000&#b1;5,000); co-factor: nicotinamide ad... | 10/15/2002 |
| 6465698 | Catalytic isomerization of Z-pentol to E-pentol A process for catalytically isomerizing Z-3-methylpent-2-en-4-yn-1-ol to E-3-methylpent-2-en-4-yn-1-ol is provided. This process includes contacting a stereoisomeric mixture containing Z-3-methylpent-2-en-4-yn-1-ol and E-3-methylpent-2-en-4-yn-1-ol with a... | 10/15/2002 |
| 6462219 | Process for producing 3-hydroxypropionitrile A process for the production of 3-hydroxypropionitrile is provided. This process includes (a) reacting acrylonitrile with water at a defined molar ratio in the presence of a weak base under specific temperature and pressure conditions until a conversion i... | 10/08/2002 |
| 6455707 | Process for the preparation of substitued pyranes Substituted pyranes such as 2-ethinyl-tetrahydro-2,6,6-trimethylpyran are prepared from dehydrolinalool or higher homologues thereof by heating or treatment with microwaves in the presence of a solid acid.... | 09/24/2002 |
