Did You Know...
...that the x-ray was discovered purely by accident? When German physicist Wilhelm Konrad von Roentgen was experimenting with cathode rays in 1895, he put an activated Crookes tube in a book and went out to lunch. When he returned, he discovered that a key that had also been placed in the book showed up as an image on the developed film!
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| Number | Title | Issue Date |
| 8143035 | Pantothenate kinase overexpression and pantothenic acid supplementation in actinomycetes The invention relates to the synthesis of polyketides in Actinomycetes by overexpression of pantothenate kinase and supplementation with pantothenic acid. This results in increasing in vivo CoA production and thereby drives increased production of secondary m... | 03/27/2012 |
| 8089628 | Pulsed-multiline excitation for color-blind fluorescence detection The present invention provides a technology called Pulse-Multiline Excitation or PME. This technology provides a novel approach to fluorescence detection with application for high-throughput identification of informative SNPs, which could lead to more accurate diagn... | 01/03/2012 |
| 7935511 | Aerobic succinate production in bacteria Methods of increasing yields of succinate using aerobic culture methods and a multi-mutant E. coli strain are provided. Also provided is a mutant strain of E. coli that produces high amounts of succinic acid. ... | 05/03/2011 |
| 7927859 | High molar succinate yield bacteria by increasing the intracellular NADH availability The invention relates to increasing the yield of succinate in bacteria by increasing the intracellular availability of cofactors such as NADH. ... | 04/19/2011 |
| 7901924 | Increased bacterial CoA and acetyl-CoA pools Methods of increasing the cellular pool of A-CoA and thus driving the metabolic pathways in the direction of A-CoA containing metabolites by overexpressing rate limiting enzymes in A-CoA synthesis. Methods of increasing intracellular levels of CoA and A-CoA through ... | 03/08/2011 |
| 7790416 | Mutant strain with increased succinic acid production The invention relates to a mutant strain of bacteria, which either lacks or contains mutant genes for several key metabolic enzymes, and which produces high amounts of succinic acid under anaerobic conditions. ... | 09/07/2010 |
| 7709261 | Recycling system for manipulation of intracellular NADH availability The present invention describes a novel recombinant NADH recycling system that is used as a process for producing reduced compounds. In a specific embodiment, the reduced compounds include ethanol, succinate, lactate, a vitamin, a pharmaceutical and a biodegraded or... | 05/04/2010 |
| 7651697 | Nitric oxide-producing hydrogel materials Hydrogels releasing or producing NO, most preferably polymerizable biodegradable hydrogels capable of releasing physiological amounts of NO for prolonged periods of time, are applied to sites on or in a patient in need of treatment thereof for disorders such as rest... | 01/26/2010 |
| 7635592 | Tissue engineering scaffolds promoting matrix protein production Matrix-enhancing molecules, such as TGF-β, are conjugated to or immobilized on scaffolds to increase ECM production by cells for tissue engineering, tissue regeneration and wound healing applications. The matrix-enhancing molecule is conjugated to a tether, such as... | 12/22/2009 |
| 7629120 | Method for assembling PCR fragments of DNA A process for assembling a series of DNA fragments generated by PCR into an ordered circular arrangement for replication and genetic work in cells. The PCR fragments are made with a modified nucleotide in the primers that can be removed with a DNA excision repair en... | 12/08/2009 |
| 7569380 | Simultaneous anaerobic production of isoamyl acetate and succinic acid In vivo method of producing esters from acetyle coA, such as isoamyl acetate and succinate, has been developed by producing null mutants in pathways that use acetyl coA and by overexpressing products that use NADH and in order to maintain the proper redox balance be... | 08/04/2009 |
| 7432090 | Blocking sporulation by inhibiting SpoIIE We have shown that the control of solventogenesis and sporulation can be genetically uncoupled in C. acetobutylicum. In strain 824(pASspo), the absence of SpoIIE causes sporulation to be blocked at stage II. The cell remains in a vegetative state, and this al... | 10/07/2008 |
| 7338915 | Ropes of single-wall carbon nanotubes and compositions thereof This invention provides a method of making single-wall carbon nanotubes by laser vaporizing a mixture of carbon and one or more Group VIII transition metals. Single-wall carbon nanotubes preferentially form in the vapor and the one or more Group VIII transition meta... | 03/04/2008 |
| 7326557 | Increasing intracellular NADPH availability in A method of increasing cellular NADPH levels by expressing one or more genes that encode a enzyme that causes the production of NADPH. The system can be combined with other enzymes that require NADPH, thus improving the overall production of the desired protein.... | 02/05/2008 |
| 7279176 | Nitric oxide-producing hydrogel materials Hydrogels releasing or producing NO, most preferably photopolymerizable biodegradable hydrogels capable of releasing physiological amounts of NO for prolonged periods of time, are applied to sites on or in a patient in need of treatment thereof for disorders such as... | 10/09/2007 |
| 7271747 | Method and apparatus for distributed compressed sensing A method for approximating a plurality of digital signals or images using compressed sensing. In a scheme where a common component xc of said plurality of digital signals or images an innovative component xi of each of said plurality of digital... | 09/18/2007 |
| 7267984 | Recombination assembly of large DNA fragments A method of assembling large DNA fragments in a chromosome using site specific recombinases and alternating excisionases. The method may be performed in vitro or in vivo, but larger assemblies are possible when the assembly is performed in vivo. For an in vivo assem... | 09/11/2007 |
| 7262046 | Aerobic succinate production in bacteria Methods of increasing yields of succinate using aerobic culture methods and a multi-mutant E. coli strain are provided. Also provided is a mutant strain of E. coli that produces high amounts of succinic acid. ... | 08/28/2007 |
| 7256016 | Recycling system for manipulation of intracellular NADH availability The present invention describes a novel recombinant NADH recycling system that is used as a process for producing reduced compounds. In a specific embodiment, the reduced compounds include ethanol, succinate, lactate, a vitamin, a pharmaceutical and a biodegraded or... | 08/14/2007 |
| 7244610 | Aerobic succinate production in bacteria Methods of increasing yields of succinate using aerobic culture methods and a multi-mutant E. coli strain are provided. Also provided is a mutant strain of E. coli that produces high amounts of succinic acid. ... | 07/17/2007 |
| 7223567 | Mutant strain with increased succinic acid production The invention relates to a mutant strain of bacteria, which either lacks or contains mutant genes for several key metabolic enzymes, and which produces high amounts of succinic acid under anaerobic conditions. ... | 05/29/2007 |
| 7157427 | Antimicrobial proteins from the SPO1 bacteriophage Anti-bacterial peptides are provided which are derived from the bacteriophage SPO1. ... | 01/02/2007 |
| 7052711 | Nitric oxide-producing hydrogel materials Hydrogels releasing or producing NO, most preferably polymerizable biodegradable hydrogels capable of releasing physiological amounts of NO for prolonged periods of time, are applied to sites on or in a patient in need of treatment thereof for disorders such as rest... | 05/30/2006 |
| 6995841 | Pulsed-multiline excitation for color-blind fluorescence detection The present invention provides a technology called Pulse-Multiline Excitation or PME. This technology provides a novel approach to fluorescence detection with application for high-throughput identification of informative SNPs, which could lead to more accurate diagn... | 02/07/2006 |
| 6706691 | Immunosupportive drug sparing diet The present invention is directed to immunosupportive, drug sparing diets and methods of using these diets. The compositions and methods disclosed herein increase the bioavailability of pharmaceutical compositions metabolized by the gut P450 isozymes. ... | 03/16/2004 |
| 6685730 | Optically-absorbing nanoparticles for enhanced tissue repair This invention is generally in the field of improved methods for the localized delivery of heat and the use thereof for the repair of tissue. The method involves localized induction of hyperthermia in tissue or materials by delivering nanoparticles to the... | 02/03/2004 |
| 6530944 | Optically-active nanoparticles for use in therapeutic and diagnostic methods This invention is generally in the field of improved methods for the localized delivery of heat and the localized imaging of biological materials. The delivery may be in vitro or in vivo and is useful for the localized treatment of cancer, inflammation or... | 03/11/2003 |
| 6292559 | Spectral optimization and joint signaling techniques with upstream/downstream separation for communication in the presence of crosstalk A system and method for determining transmission characteristics for a communications channel and for transmitting data on the communications channel. In one embodiment, the method starts by determining the channel's transfer function and determining inte... | 09/18/2001 |
| 6207130 | Metal-exchanged carboxylato-alumoxanes and process of making metal-doped alumina A method has been developed for the solution-based metal exchange of carboxylato-alumoxanes [Al(O)x (OH)y (O2 CR)z ]n with a wide range of metal cations. Metal-exchanged carboxylato-alumoxanes are new... | 03/27/2001 |
| 6183714 | Method of making ropes of single-wall carbon nanotubes This invention provides a method of making single-wall carbon nanotubes by laser vaporizing a mixture of carbon and one or more Group VIII transition metals. Single-wall carbon nanotubes preferentially form in the vapor and the one or more Group VIII tran... | 02/06/2001 |
| 6002259 | Electrostatic adhesion tester for thin film conductors A electrostatic adhesion tester for thin film conductors. In one embodiment, a device is provided for testing the adhesion strength of a thin film conductor that has been formed upon a substrate. The device includes an adhesion tester that is primarily co... | 12/14/1999 |
| 5760941 | System and method for performing optical code division multiple access communication using bipolar codes An optical encoding and decoding system which performs code-division multiple access (CDMA) communication in the incoherent, or direct detection, optical domain using bipolar +1/-1 codes. The present invention uses code modulation and detection principles... | 06/02/1998 |
| 5644005 | Method of making poly(propylene fumarate-coethylene oxide) A biodegradable block copolymer made from the transesterfication of a poly(propylene fumarate) prepolymer and a poly(ethylene oxide) prepolymer. The block copolymer poly(propylene fumarate -co- ethylene oxide) is capable of crosslinking at body temperatur... | 07/01/1997 |
| 5589231 | Halogen-activated chemical vapor deposition of diamond The present invention is directed to a method of producing diamond films through the thermal dissociation of molecular chlorine into atomic chlorine in a heated graphite heat exchanger at temperatures of from about 1,100° C. to about 1,800° C. The atomi... | 12/31/1996 |
| 5522895 | Biodegradable bone templates A biodegradable, bioresorbable, three-dimensional template for repair and replacement of diseased or injured bone which provides mechanical strength to bone while also providing a guide for growth of bone tissue. Preferably, the template is formed of biod... | 06/04/1996 |
| 5249295 | Digital computer register allocation and code spilling using interference graph coloring A method is disclosed for allocating internal machine registers in a digital computer for use in storing values defined and referenced by a computer program. An allocator in accordance with the present invention constructs a interference graph having a no... | 09/28/1993 |
