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Assignee: Research Triangle Pharmaceuticals


Location: Durham, NC
No. of patents: 6

NumberTitleIssue Date
6465016Cyclosporiine particles
Pharmaceutical compositions containing solid cyclic oligopeptide cyclosporine microparticles are prepared by applying energy input to solid cyclic oligopeptide cyclosporine in the presence of phospholipid and one or more non-ionic, anionic or cationic sec...
10/15/2002
6228399Composition and method of preparing microparticles of water-insoluble substances
Pharmaceutical compositions containing cyclosporin microparticles are prepared by applying energy to cyclosporin particles in the presence of phospholipid and one or more surface modifiers. These microparticles consist essentially of cyclosporin, a phosph...
05/08/2001
5922355Composition and method of preparing microparticles of water-insoluble substances
Submicron size particles of pharmaceutical or other water-insoluble or poorly water-insoluble substances are prepared using a combination of one or more surface modifiers/surfactants such as polaxomers, poloxamines, polyoxyethylene sorbitan fatty acid est...
07/13/1999
5785975Adjuvant compositions and vaccine formulations comprising same
The present invention relates to phospholipid-polysaccharide adjuvant compositions and to vaccine formulations comprising same, as well as to methods of making and using such adjuvants and vaccines....
07/28/1998
5660858Cyclosporin emulsions
This invention comprises pharmaceutical compositions consisting essentially of an oil-in-water emulsion containing a synthetic medium chain triglyceride in which is dissolved a therapeutically effective amount of a cyclosporin, phospholipid and optionally...
08/26/1997
5637625Propofol microdroplet formulations
Formulations of phospholipid-coated microdroplets of propofol devoid of fats and triglycerides provide chronic sedation over extended periods of time without fat overload. Being free of nutrients that support bacterial growth, these microdroplet formulati...
06/10/1997
 
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