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| Number | Title | Issue Date |
| 8173678 | Kappa opioid receptor ligands Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor su... | 05/08/2012 |
| 8129834 | Integral metal structure with conductive post portions A plurality of FPGA dice is disposed upon a semiconductor substrate. In order to supply the immense power required by the plurality of FPGA dice, power is routed through the semiconductor substrate vertically from thick metal layers and large integral metal structur... | 03/06/2012 |
| 8088324 | Electrospray/electrospinning apparatus and method Apparatus and method for producing fibrous materials in which the apparatus includes an enclosure having an inlet configured to receive a substance from which the fibrous materials are to be composed, a common electrode disposed in the enclosure, and plural extrusio... | 01/03/2012 |
| 8052932 | Polymer nanofiber-based electronic nose A chemical sensor and a system and method for sensing a chemical species. The chemical sensor includes a plurality of nanofibers whose electrical impedance varies upon exposure to the chemical species, a substrate supporting and electrically isolating the fibers, an... | 11/08/2011 |
| 8052407 | Electrospinning in a controlled gaseous environment Apparatus and method for producing fibrous materials in which the apparatus includes an electrospinning element configured to electrospin a substance from which the fibers are to be composed by an electric field extraction of the substance from a tip of the electros... | 11/08/2011 |
| 8048895 | Kappa opioid receptor ligands Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor su... | 11/01/2011 |
| 8035223 | Structure and process for electrical interconnect and thermal management A structure and method for thermal management of integrated circuits. The structure for thermal management of integrated circuits includes first and second substrates bonded together, at least one of the first and second substrates including at least one circuit ele... | 10/11/2011 |
| 8008134 | Large substrate structural vias An electronic package and methods by which the package reduces thermal fatigue failure of conductors in the electronic package. The electronic package includes a carrier substrate having first and second surfaces and a plurality of anchor vias having a via material ... | 08/30/2011 |
| 7999455 | Luminescent device including nanofibers and light stimulable particles disposed on a surface of or at least partially within the nanofibers A device for stimulable light emission that includes a fiber mat of nanofibers having an average fiber diameter in a range between 100 and 2000 nm, and includes plural stimulable particles disposed in association with the nanofibers. The stimulable particles produce... | 08/16/2011 |
| 7999388 | Preventing breakage of long metal signal conductors on semiconductor substrates An apparatus includes a volume of insulator disposed over a top surface of a semiconductor substrate, a tube of soft dielectric, and a metal conductor. The insulator has a hardness of more than approximately three gigapascals (gPa) and the soft dielectric has a hard... | 08/16/2011 |
| 7978029 | Multiple-layer signal conductor A multiple-layer signal conductor has increased surface area for mitigation of skin effect. Parallel extending elongated strips of conductive material are placed in parallel layers and are separated by a thin layer of dielectric. The elongated strips are conductivel... | 07/12/2011 |
| 7956006 | Process for preparing zinc oxide-based sorbents The disclosure relates to zinc oxide-based sorbents, and processes for preparing and using them. The sorbents are preferably used to remove one or more reduced sulfur species from gas streams. The sorbents comprise an active zinc component, optionally in combination... | 06/07/2011 |
| 7944041 | Integrated semiconductor substrate structure using incompatible processes A plurality of FPGA dice is disposed upon a semiconductor substrate. In order both to connect thousands of signal interconnect lines between the plurality of FPGA dice and to supply the immense power required, it is desired that the substrate construction include tw... | 05/17/2011 |
| 7923410 | Regenerable sorbents for removal of sulfur from hydrocarbons and processes for their preparation and use A sorbent for use in removing sulfur contaminants from hydrocarbon feedstocks is provided, wherein the sorbent contains zinc aluminate in an amount of at least 40 wt % (calculated as ZnAl2O4); free alumina in an amount of from about 5 wt % to a... | 04/12/2011 |
| 7872023 | Kappa opioid receptor ligands Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor su... | 01/18/2011 |
| 7789930 | Particle filter system incorporating nanofibers A filtration device including a filtration medium having a plurality of nanofibers of diameters less than 1 micron formed into a fiber mat in the presence of an abruptly varying electric field. The filtration device includes a support attached to the filtration medi... | 09/07/2010 |
| 7762801 | Electrospray/electrospinning apparatus and method Apparatus and method for producing fibrous materials in which the apparatus includes an enclosure having an inlet configured to receive a substance from which the fibrous materials are to be composed, a common electrode disposed in the enclosure, and plural extrusio... | 07/27/2010 |
| 7706152 | DC-DC converter for low voltage power source A power conversion unit and method for converting DC power. The power conversion unit includes a self-oscillating device configured to convert a DC voltage into a self-oscillating alternating current AC signal, a transformer connected to the self-oscillating device ... | 04/27/2010 |
| 7682423 | Zinc-oxide-based sorbents and processes for preparing and using same Zinc oxide-based sorbents, and processes for preparing and using them are provided. The sorbents are preferably used to remove one or more reduced sulfur species from gas streams. The sorbents comprise an active zinc component, optionally in combination with one or ... | 03/23/2010 |
| 7615567 | Compounds and methods for promoting smoking cessation Compounds and methods for promoting smoking cessation. The compounds may be used to treat a variety of other conditions and disease states. ... | 11/10/2009 |
| 7592277 | Nanofiber mats and production methods thereof An apparatus and method in which the apparatus includes a first electrospinning device configured to electrospin first fibers of a first substance, a second electrospinning device configured to electrospin second fibers of a second substance such that first and seco... | 09/22/2009 |
| 7544696 | Spermicidal and/or antifungal composition and methods of using the same Hexahydroindenopyridine compounds are provided which act as spermicides and/or fungicides, spermicidal and/or fungicidal compositions containing the same, and methods for killing motile sperm and/or fungi using the compounds and compositions. ... | 06/09/2009 |
| 7496295 | Optical-inclusive dWDM local area network An optical-inclusive, dWDM local area network and the accompanying signaling protocol necessary to facilitate communication between nodes in a network. This network architecture provides for a packet-oriented network, independent of the number of nodes and the numbe... | 02/24/2009 |
| 7495638 | Visual display with increased field of view This invention provides a continuous display with non-uniform pixel density, forming a foveated display. A single, continuous display has a higher pixel density at the center of the display than at the periphery of the display. Where two continuous displays are used... | 02/24/2009 |
| 7476679 | Octahydroisoquinoline compounds as opioid receptor modulators Compounds which bind to opioid receptors are provided. In a preferred embodiment of the invention, the compounds are opioid receptor antagonists. The present invention also provides methods of treating conditions which are mediated by an opioid receptor. ... | 01/13/2009 |
| 7449821 | Piezoelectric micromachined ultrasonic transducer with air-backed cavities A piezoelectric micromachined ultrasonic transducer comprising a substrate and a first dielectric film formed on the substrate. An opening having a sidewall is formed through the substrate and first dielectric film. A bottom electrode is formed on the first dielectr... | 11/11/2008 |
| 7399762 | Opioid receptor agonist compounds and their use in treatment of pain Structurally novel opioid receptor agonists are provided, and the use of these agonists in treatment of chronic and/or acute pain. ... | 07/15/2008 |
| 7350234 | Intrusion tolerant communication networks and associated methods An intrusion tolerant communication network and related methods is provided that places emphasis on continuity of operation and provides for an attack-survivable communication network whose network devices collectively accomplish the specified networking intent even... | 03/25/2008 |
| 7297305 | Electrospinning in a controlled gaseous environment Apparatus and method for producing fibrous materials in which the apparatus includes an extrusion element configured to electrospin a substance from which the fibers are to be composed by an electric field extraction of the substance from a tip of the extrusion elem... | 11/20/2007 |
| 7291737 | Cocaine receptor binding ligands A class of binding ligands for cocaine receptors and other receptors in the brain. Specifically, a novel family of compounds shows high binding specificity and activity, and, in a radiolabeled form, can be used to bind to these receptors, for biochemical assays and ... | 11/06/2007 |
| 7291259 | Process for desulfurizing hydrocarbon fuels and fuel components Processes are disclosed for removing sulfur, including cyclic and polycyclic organic sulfur components such as thiophenes and benzothiophenes, from a hydrocarbon feedstock including fuels and fuel components. The feedstock is contacted with a regenerable sorbent mat... | 11/06/2007 |
| 7282798 | Spontaneous emission enhanced heat transport method and structures for cooling, sensing, and power generation A method and structure for heat transport, cooling, sensing and power generation is described. A photonic bandgap structure (3) is employed to enhance emissive heat transport from heat sources such as integrated circuits (2) to heat spreaders (4... | 10/16/2007 |
| 7259286 | Attrition resistant bulk iron catalysts and processes for preparing and using same An attrition resistant precipitated bulk iron catalyst is prepared from iron oxide precursor and a binder by spray drying. The catalysts are preferably used in carbon monoxide hydrogenation processes such as Fischer-Tropsch synthesis. These catalysts are suitable fo... | 08/21/2007 |
| 7189737 | Cocaine receptor binding ligands A class of binding ligands for cocaine receptors and other receptors in the brain. Specifically, a novel family of compounds shows high binding specificity and activity, and, in a radiolabeled form, can be used to bind to these receptors, for biochemical assays and ... | 03/13/2007 |
| 7164077 | Thin-film thermoelectric cooling and heating devices for DNA genomic and proteomic chips, thermo-optical switching circuits, and IR tags A thermoelectric cooling and heating device including a substrate, a plurality of thermoelectric elements arranged on one side of the substrate and configured to perform at least one of selective heating and cooling such that each thermoelectric element includes a t... | 01/16/2007 |
| 7134857 | Electrospinning of fibers using a rotatable spray head Apparatus and method for electrospinning fibers in which the apparatus includes a spray head having a longitudinal axis and including at least one electrospinning element disposed in a peripheral wall of the spray head surrounding the longitudinal axis. The electros... | 11/14/2006 |
| 7112536 | Plasma processing system and method A plasma processing system and method wherein a power source produces a magnetic field and an electric field, and a window disposed between the power source and an interior of a plasma chamber couples the magnetic field into the plasma chamber thereby to couple powe... | 09/26/2006 |
| 7076801 | Intrusion tolerant server system The invention relates to a reconfigurable scalable intrusion-tolerant network that is interposed between a service requesting client and a protected server to minimize the impact of intrusive events. The apparatus may include a proxy server for receiving the request... | 07/11/2006 |
| 7071204 | Camptothecin analogs having an E-ring ketone Camptothecin analogs having an E-ring ketone are effective anti tumor compounds. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I DNA cleavable complex. ... | 07/04/2006 |
| 7067666 | 7-substituted camptothecin and camptothecin analogs and methods for producing the same Methods of forming camptothecin compounds which are effective anti-tumor compounds are disclosed. These compounds inhibit the enzyme topoisomerase I and may alkylate DNA of the associated topoisomerase I-DNA cleavable complex. ... | 06/27/2006 |
