Celebrity Inventors
Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 8058053 | Modification of protein glycosylation in methylotrophic yeast The present invention relates to methods and genetically engineered methylotrophic yeast strains for producing glycoproteins with mammalian-like glycosylation. The present invention also relates to vectors useful for generating methylotrophic yeast strains capable o... | 11/15/2011 |
| 7811233 | Finite amplitude distortion-based inhomogeneous pulse echo ultrasonic imaging A method and system for imaging a sample. The method includes the steps of generating an ultrasonic signal, directing the signal into a sample, which signal is distorted and contains a first order and higher order component signals at first and higher frequencies re... | 10/12/2010 |
| 7745200 | Formaldehyde dehydrogenase genes from methylotrophic yeasts The present invention provides formaldehyde dehydrogenase genes (FLD) from methylotrophic yeasts. The FLD structural genes confer resistance to formaldehyde and are therefore useful as a selectable marker in methylotrophic yeasts. The FLD promoter sequences are stro... | 06/29/2010 |
| 7507573 | Modification of protein glycosylation in methylotrophic yeast The present invention relates to methods and genetically engineered methylotrophic yeast strains for producing glycoproteins with mammalian-like glycosylation. The present invention also relates to vectors useful for generating methylotrophic yeast strains capable o... | 03/24/2009 |
| 7250502 | Formaldehyde dehydrogenase genes from methylotrophic yeasts The present invention provides formaldehyde dehydrogenase genes (FLD) from methylotrophic yeasts. The FLD structural genes confer resistance to formaldehyde and are therefore useful as a selectable marker in methylotrophic yeasts. The FLD promoter sequences are stro... | 07/31/2007 |
| 7186859 | Uses for amino acid anticonvulsants The present invention is directed to the use of compounds of the formula: for treating pain, in particular neuropathic pain, bipolar disease and migraine headaches. ... | 03/06/2007 |
| 7153661 | Artificial antibody polypeptides A fibronectin type III (Fn3) polypeptide monobody, a nucleic acid molecule encoding said monobody, and a variegated nucleic acid library encoding said monobody, are provided by the invention. Also provided are methods of preparing a Fn3 polypeptide monobody, and kit... | 12/26/2006 |
| 7148378 | Uses for amino acid anticonvulsants The present invention is directed to the use of compounds of the formula: for treating pain, in particular neuropathic pain, bipolar disease and migraine headaches. ... | 12/12/2006 |
| 7119171 | Binding polypeptides The present invention provides modified fibronectin type III (Fn3) molecules, nucleic acid molecules encoding the modified Fn3 molecules, and related vectors and host cells. ... | 10/10/2006 |
| 7104956 | Finite amplitude distortion-based inhomogeneous pulse echo ultrasonic imaging A method and system for imaging a sample. The method includes the steps of generating an ultrasonic signal, directing the signal into a sample, which signal is distorted and contains a first order and higher order component signals at first and higher frequencies re... | 09/12/2006 |
| 7078490 | Artificial antibody polypeptides A fibronectin type III (Fn3) polypeptide monobody, a nucleic acid molecule encoding a monobody, and a variegated nucleic acid library encoding a monobody, are provided by the invention. Also provided are methods of preparing an Fn3 polypeptide monobody, and kits to ... | 07/18/2006 |
| 7030099 | Tumor specific promoters of the midkine gene that allow for selective expression in P53-inactivated cells A DNA comprising a 609 bp base sequence from −559 to +50 when the first base sequence of exon 1 of the midkine gene, a human retinoic acid-responsive growth/differentiation factor was set as +1, or a DNA comprising a 251 bp base sequence from −213 to +38 when th... | 04/18/2006 |
| 7011831 | Recombinant α-galactosidase A therapy for Fabry disease Fabry disease results from an X-linked deficiency in the enzyme α-galactosidase A. The present invention is directed to recombinant human α-galactosidase A and provides baculovirus expression vectors and recombinant virus that provide stable expression of extracel... | 03/14/2006 |
| 7004905 | Finite amplitude distortion-based inhomogeneous pulse echo ultrasonic imaging A method and system for imaging a sample. The method includes the steps of generating an ultrasonic signal, directing the signal into a sample, which signal is distorted and contains a first order and higher order component signals at first and higher frequencies re... | 02/28/2006 |
| RE38947 | Method of enantioselectively catalyzing a reaction A chiral catalyst is disclosed together with methods of using it for enantioselective syntheses. The chiral catalyst includes a nucleus with two metal atoms that has four bridging ligands oriented radially to the axis of the nucleus. Each of these ligands includes a... | 01/24/2006 |
| 6906054 | Compositions for inhibiting beta-lactamase The invention provides pharmaceutical compositions comprising compounds of formula I and IV: wherein R1-R11 and A have any of the values defined in the specification, and ... | 06/14/2005 |
| 6884910 | Uses for amino acid anticonvulsants The present invention is directed to the use of compounds of the formula: for treating pain, in particular neuropathic pain, bipolar disease and migraine headaches. ... | 04/26/2005 |
| 6861245 | Production of heterologous polypeptides from freshwater caulobacter A method is provided for screening Caulobacter suitable for use as host organisms for secretion of heterologous polypeptides. Such Caulobacter have a transport protein homologous to one of the type I transport proteins known in C. crescentus. DN... | 03/01/2005 |
| 6825347 | Uronium and immonium salts for peptide coupling The present invention is directed to salts of the formula: or N-oxides thereof, and their use in preparing an amide. ... | 11/30/2004 |
| 6770261 | Magnetic resonance imaging agents for the detection of physiological agents The invention relates to novel magnetic resonance imaging contrast agents and methods of detecting physiological signals or substances. ... | 08/03/2004 |
| 6770759 | Penicillanic acid derivative compounds and methods of making Compound of formula I: wherein R1, R2, R3, R4 and n have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting ... | 08/03/2004 |
| RE38551 | Anticonvulsant enantiomeric amino acid derivatives The present invention is directed to a compound in the R configuration about the asymmetric carbon in the following formula: pharmaceutical compositions containing same and the use thereof in treating CNS disorders in animals. ... | 07/06/2004 |
| 6730499 | Promoter for the Pichia pastoris formaldehyde dehydrogenase gene FLD1 The present invention provides formaldehyde dehydrogenase genes (FLD) from methylotrophic yeasts. The FLD structural genes confer resistance to formaldehyde and are therefore useful as a selectable marker in methylotrophic yeasts. The FLD promoter sequences are stro... | 05/04/2004 |
| 6723697 | IL-16 antagonists In accordance with the present invention, novel IL-16 antagonists, preferably peptides derived from CD4, have been isolated and synthesized. These peptides possess IL-16 antagonistic properties including the ability to selectively bind to IL-16 and inhibit IL-16-med... | 04/20/2004 |
| 6713046 | Magnetic resonance imaging agents for the delivery of therapeutic agents The invention relates to novel magnetic resonance imaging contrast agents and methods of delivering therapeutically active agents. ... | 03/30/2004 |
| 6713045 | Targeted magnetic resonance imaging agents for the detection of physiological processes The invention relates to novel targeted magnetic resonance imaging contrast agents and methods of detecting physiological signals or substances. ... | 03/30/2004 |
| 6703199 | Artificial antibody polypeptides A fibronectin type III (Fn3) polypeptide monobody, a nucleic acid molecule encoding said monobody, and a variegated nucleic acid library encoding said monobody, are provided by the invention. Also provided are methods of preparing a Fn3 polypeptide monobo... | 03/09/2004 |
| 6699466 | IL-16 antagonist peptides and DNA encoding the peptides The present invention has found that a series of peptides having sequences that substantially correspond to specific regions of the C-terminus of IL-16 can inhibit the activity of IL-16. The present invention has demonstrated that such IL-16-inhibiting pe... | 03/02/2004 |
| 6673333 | Functional MRI agents for cancer imaging The invention relates to novel magnetic resonance imaging contrast agents for imaging cancer.... | 01/06/2004 |
| 6673901 | Artificial antibody polypeptides A fibronectin type III (Fn3) polypeptide monobody, a nucleic acid molecule encoding said monobody, and a variegated nucleic acid library encoding said monobody, are provided by the invention. Also provided are methods of preparing a Fn3 polypeptide monobo... | 01/06/2004 |
| 6670193 | Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same The present invention provides fluorescent nucleoside analogs which comprise a fluorescent cyclic compound joined to a carbon of a sugar molecule such as pentose, hexose, ribose or deoxyribose or analogs thereof in either an or ଲ configurati... | 12/30/2003 |
| 6645725 | Diagnostic assay for endometriosis The present invention provides a method for detecting endometriosis in a patient and is an improvement over invasive and expensive surgical procedures. The method employs immunoassays which detect autoantibodies in a serum sample which react with Thomsen-... | 11/11/2003 |
| 6638504 | Methods for treating cancer The present invention is directed towards the diagnosis of malignant cancer by detection of the mts-1 MRNA or the mts-1 protein, encoded by the mts-1 gene. The present invention contemplates the use of recombinant mts-1 DNA and antibodies directed against... | 10/28/2003 |
| 6602861 | Acylated phospholipid drugs This invention relates to a method for improving the efficiency of a drug containing a free carboxy group, the improvement comprising esterifying said carboxy group to the hydroxy group of the glycerol portion of a glycerolphospholipid ester having the fo... | 08/05/2003 |
| 6599892 | 7-alkylidene cephalosporanic acid derivatives and methods of using the same Derivatives of 7-alkylidene cephalosporanic acid sulfone and the pharmaceutically active salts thereof are found to be potent inhibitors of ଲ-lactamase enzymes.... | 07/29/2003 |
| 6534627 | Synthesis and use of amino acid fluorides as peptide coupling reagents The present invention is directed to the process of preparing a peptide comprising reacting a first amino acid or peptide with an amino acid fluoride of the formula: ##STR1## or the acid fluoride salts thereof wherein BLK is an N-amino protecting group; A... | 03/18/2003 |
| 6517811 | Compounds for cancer imaging and therapy The present invention relates to a class of compounds having affinity for certain cancer cells, e.g. lung carcinomas, colon carcinomas, renal carcinomas, prostate carcinomas, breast carcinomas, malignant melanomas, gliomas, neuroblastomas and pheochromocy... | 02/11/2003 |
| 6479650 | Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same The present invention provides fluorescent nucleoside analogs which comprise a fluorescent cyclic compound joined to a carbon of a sugar molecule such as pentose, hexose, ribose or deoxyribose or analogs thereof in either an or ଲ configurati... | 11/12/2002 |
| 6462189 | Nucleic acids encoding artificial antibody polypeptides A fibronectin type III (Fn3) polypeptide monobody, a nucleic acid molecule encoding the monobody, and a variegated nucleic acid library encoding the monobody, are provided by the invention. Also provided are methods of preparing a Fn3 polypeptide monobody... | 10/08/2002 |
| 6447748 | Benzamide compounds for cancer imaging and therapy The present invention relates to a class of compounds having affinity for certain cancer cells, e.g. lung carcinomas, colon carcinomas, renal carcinomas, prostate carcinomas, breast carcinomas, malignant melanomas, gliomas, neuroblastomas and pheochromocy... | 09/10/2002 |
