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| Number | Title | Issue Date |
| 5099010 | Intermediates in the preparation of 3'-amino-2',3'-dideoxycytidine and the pharmacologically acceptable salts thereof This disclosure describes the preparation of 3'-amino-2', 3'-dideoxyctidine and the pharmacologically acceptable salts thereof which are useful in inhibiting the growth of transplanted tumors in mammals.... | 03/24/1992 |
| 5064862 | Anticonvulsant method and formulations This invention relates to certain aminobenzanilide compounds, and to the use, in the treatment of mammals, of certain aminobenzanilide compounds as anticonvulsant agents.... | 11/12/1991 |
| 5023108 | Aqueous dispersions of waxes and lipids for pharmaceutical coating This invention relates to the coating of pharmaceutically useful solids with an emulsion comprising a wax/lipid, an emulsifying agent and water, which emulsion can be spray dried to form a powder which can subsequently be dispersed in water and coated ont... | 06/11/1991 |
| 4994462 | Platelet aggregation inhibitory agents and intermediate therefor This invention relates to certain N,N'-bis(nipecotyl)piperazines and their use as platelet aggregation inhibtory agents.... | 02/19/1991 |
| 4968619 | Modified microorganisms and method of preparing and using same Microorganisms have been developed which may be characterized as possessing substantially all of the following qualities or capabilities: (a) capable of having foreign genetic information introduced thereinto and recovered therefrom along with its expression w... | 11/06/1990 |
| 4956280 | Biphasic shuttle vectors This invention provides a biphasic shuttle vector capable replication and expression of foreign genetic information in Escherichia coli and Agmenellum quadruplicatum comprising an E. coli replicon, an A. quadruplicatum replicon, at least two selectable ma... | 09/11/1990 |
| 4925477 | Chemical hybridizing agents The present invention relates to a method for inducing male sterility in plants which comprises treating seeds of a plant receptive to said treatment by application of an effective amount of a compound of the formula: ##STR1## wherein R and R | 05/15/1990 |
| 4921790 | Tumor specific assay for CA125 ovarian cancer antigen The present invention relates to a 40 kilodalton subunit of serous cystadinocarcinoma ovarian tumor associated antigen CA125, useful in the diagnosis and monitoring of ovarian cancer. It also relates to an immunoassay method for detection of the antigen i... | 05/01/1990 |
| 4888170 | Vaccines obtained from antigenic gene products of recombinant genes This invention relates to a vaccine for the immunization of a vertebrate, comprising: an avirulent derivative of a pathogenic microbe that expresses a recombinant gene derived from a pathogen of said vertebrate it being provided that said avirulent microb... | 12/19/1989 |
| 4866175 | Novel process for the synthesis of quinoxaline and benzimidazole-N-oxides The synthesis of quinoxaline and benzimidazole-N-oxides and of ester amd amide derivatives of 3-hydroxy-2-quinoxalinecarboxylic acid by a movel process consisting of the reaction between a benzofuroxan and an activated methylene-containing compound under ... | 09/12/1989 |
| 4863967 | N,N-diaminophthalamides A compound having the structural formula ##STR1## wherein R1 and R2 are the same or different and are hydrogen, C1 -C6 alkyl, halogen or C1 -C4 alkoxy is disclosed. These compounds dem... | 09/05/1989 |
| 4861721 | Bacteria for cellulose digestion This invention relates to a process for the microbial degradation of cellulosic material. More specifically, this invention relates to a process for the digestion of cellulose by a microbe capable of carrying out the cellulolytic combined nitrogen.... | 08/29/1989 |
| 4857474 | Phycoerythrins useful in fluorescent conjugates This invention provides a class of phycoerythrins useful in diagnostic and detection protocols wherein a fluorescent label is required. The unique spectral properties of the phycoerythrins described herein provide for increased sensitivity and alternative... | 08/15/1989 |
| 4852973 | Diffraction free arrangement Arrangements are disclosed for generating a well defined traveling wave beam substantially unaffected by diffractive spreading. In different embodiments, the beam can be an electromagnetic wave, particle beam, a transverse beam, a longitudinal beam such a... | 08/01/1989 |
| 4829031 | Method of preparing ceramic compositions at lower sintering temperatures Ceramic oxide diphasic xerogels of structurally dissimilar phases (crystalline and amorphous, semicrystalline or noncrystalline) but compositionally similar phases will be converted to crystalline ceramic oxide products having enhanced densification when ... | 05/09/1989 |
| 4828764 | N-Fluoro-N-Perfluoromethyl sulfonamides N-fluoro-N-perfluoromethyl sulfonamide compounds are provided as fluorinating agents for the fluorination of organic compounds by either the direct electrophilic fluorination of organic compounds or by the fluorination of organic compound carbanions.... | 05/09/1989 |
| 4828799 | Therapeutic drug monitoring and analyte determination utilizing micellar chromatography A method for the determination of the drug or other analyte content and concentration in bodily fluids that are directly injected in a micellar chromatographic column. Various embodiments of kits are also disclosed.... | 05/09/1989 |
| 4826968 | S-alkylated coenzyme A with effect on polyamine acetylase The present invention relates to the novel compound N-[2-(S-Coenzyme A) acetyl] sym-norspermidine which electively inhibits the enzyme spermidine/spermine N1 acetyl transferase thereby aberrating the polyamine biosynthesis pathway. The present ... | 05/02/1989 |
| 4820811 | Amine reacted therapeutic agents A complex of a therapeutic agent is disclosed in which the therapeutic agent is complexed to an ammonium ion selected from the group consisting of ##STR1## where R1 and R2 are the same or different and are alkyl or hydroxy ... | 04/11/1989 |
| 4820706 | Pteridine derivatives and method of treating leukemia employing same 2,4-Diaminopteridine derivatives and the pharmaceutically acceptable salts thereof having potent anticancer activity are disclosed. The derivatives possess the structural formula: ##STR1## wherein Y is NH2, OH or SH, R is ##STR2## ... | 04/11/1989 |
| 4814612 | Method and means for vaporizing liquids for detection or analysis This disclosure is concerned with method and apparatus for vaporizing liquid solutions in order to detect, quantitate, and/or determine physical or chemical properties of samples present in liquid solution. Mixtures may be separated by an on-line liquid c... | 03/21/1989 |
| 4806568 | Gossypol derivatives This invention relates to a compound of the formula: ##STR1## wherein R1 is C.tbd.N or COR3 ; and R2 is alkyl, alkenyl, alkynyl, or acyl wherein R3 is hydrogen, alkyl, alkenyl, alkynyl, hydroxy, amino or alkoxy ... | 02/21/1989 |
| 4798830 | Platelet aggregation inhibitory agents and intermediates therefor This invention relates to tetrahydroquinoline derivatives and their use for the inhibition of blood platelet aggregation.... | 01/17/1989 |
| 4793776 | Pump for oscillating a fluid in vivo A pump for oscillating a fluid into and out from a body area. The pump forms a fluid chamber for holding the fluid, and comprises a piston for forcing fluid outward from the fluid chamber and into the body, and for drawing fluid inward from the body and i... | 12/27/1988 |
| 4790554 | Pulley shift assembly An assembly comprising a pulley sub assembly and a shift sub assembly. The pulley sub assembly includes a plurality of pulleys, each pulley includes a plurality of sections, and at least one section of each pulley is axially moveable. The shift sub assemb... | 12/13/1988 |
| 4790987 | Viral glycoprotein subunit vaccine The present invention relates to a vaccine composition useful in preparation of virus-caused disease comprising as its active agent at least one immunogenically effective amount of immunogenic viral envelope glycoprotein complexed with a lipid.... | 12/13/1988 |
| 4784150 | Surgical retractor and blood flow monitor A surgical retractor instrument which incorporates therein a blood flow monitor. A surgical retractor system is disclosed for manipulation of living tissues and/or organs during diagnostic and/or surgical procedures, providing for the monitoring of the pr... | 11/15/1988 |
| 4758596 | Method for therapeutic use of methyl tertiary-butyl ether Method for dissolving cholesterol calculus in vitro or in vivo comprising contacting the cholesterol calculus with methyl tertiary-butyl ether.... | 07/19/1988 |
| 4755167 | In vivo method for distribution and stirring of therapeutic agents Method and means for distributing therapeutic agents in a localized area of a patient's body comprising introducing a therapeutic area of a patient's body and agitating the therapeutic agent in the localized area of a patient's body by introducing an osci... | 07/05/1988 |
| 4749560 | Metal organo phosphorous compounds for NMR analysis The present invention relates to a class of compositions and a method for NMR imaging using an NMR signal affecting amount of a paramagnetic, diamagnetic or ferromagnetic metal ion chelated with an organo phosphorous compound. Gadolinium bis(bis-dihydroxy... | 06/07/1988 |
| 4740466 | Induction of settlement and metamorphosis in Crassostrea virginica by melanin-synthesizing bacteria The present invention relates to the discovery of a new bacterium, alteromonas calwellii, which has been found to attract oyster larvae by the production of a compound involved in melanin synthesis. More specifically, the present invention contemplates a ... | 04/26/1988 |
| 4734275 | Anti-curare agents This invention relates to a method for antagonizing induced the neuromuscular blocking effects of certain therapeutic agents and pathological disorders in mammals, which comprises administering to said mammal an antagonizing-effective amount of a compound... | 03/29/1988 |
| 4730111 | Ion vapor source for mass spectrometry of liquids This disclosure is concerned with method and apparatus for vaporizing liquid solutions in order to detect, quantitate, and/or determine physical or chemical properties of samples present in liquid solution. Mixtures may be separated by an on-line liquid c... | 03/08/1988 |
| 4728328 | Cuffed tubular organic prostheses A cuffed tubular vascular prosthesis and process for manufacturing the prosthesis are disclosed. A flexible tubular body is formed by coating a glass rod with a polymer solution and air-curing the coating to form a smooth outer surface. The tubular body i... | 03/01/1988 |
| 4726854 | Cast iron welding electrodes Metal filler compositions based on manganese and nickel for the welding of cast iron are disclosed. The filler composition preferably contains about 15 to 50% manganese and 15 to 35% nickel. The filler compositions may be incorporated into a welding rod f... | 02/23/1988 |
| 4725145 | Photodetector arrangement for measuring the state of polarization of light An apparatus and method for the measurement of at least one parameter of the state of polarization of a light beam is described. The apparatus includes only a photodetector and no other optical elements. The detector surface is partially specularly reflec... | 02/16/1988 |
| 4723941 | Pump for oscillating a fluid in vivo A pump for oscillating a fluid into and out from a body area. The pump forms a fluid chamber for holding the fluid, and comprises a piston for forcing fluid outward from the fluid chamber and into the body, and for drawing fluid inward from the body and i... | 02/09/1988 |
| 4720485 | Tripeptides for control of intestinal motility Peptides isolated from the bovine posterior pituitary gland are useful for the control of intestinal motility.... | 01/19/1988 |
| 4717713 | Controlled release liquid pharmaceutical A controlled release pharmaceutical composition including a solution or suspension vehicle and a pharmaceutically active agent. The composition is administered to the body in a normally liquid formulation and thereafter forms a semi-solid gel-like matrix ... | 01/05/1988 |
| 4713240 | Vaccines based on insoluble supports The present invention relates to vaccine compositions which comprise at least one antigen chemically linked to a water-insoluble support combined with a pharmaceutically acceptable carrier. It also relates to a method of stimulating an organism's immune s... | 12/15/1987 |
