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| Number | Title | Issue Date |
| 8163113 | Thermomechanical processing of aluminum alloys A cast aluminum alloy containing up to about 0.35% by weight chromium is heated to a first elevated temperature to homogenize the casting and dissolve the chromium content in an aluminum-based matrix phase. The alloy is then heated at a lower elevated temperature to... | 04/24/2012 |
| 7982069 | Switchable solvents and methods of use thereof A solvent that reversibly converts from a nonionic liquid mixture to an ionic liquid upon contact with a selected trigger, e.g., contact with CO2, is described. In preferred embodiments, the ionic solvent is readily converted back to the nonionic liquid m... | 07/19/2011 |
| 7943650 | Methods of treating cancer with imidazolyl compounds Disclosed in certain embodiments is a method of treating and/or mitigating prostate cancer, ovarian cancer, melanoma, colorectal cancer, breast cancer or lung cancer, comprising administering to an individual in need thereof a pharmaceutical composition comprising a... | 05/17/2011 |
| 7473422 | Antibodies to retinoid metabolizing protein Amino acid sequences and corresponding nucleic acid sequence of retinoid metabolizing protein found in human, mouse and zebrafish are described, as well as methods of using same. ... | 01/06/2009 |
| 7402426 | Detection of biological molecules by differential partitioning of enzyme substrates and products This invention relates to a method and apparatus for detecting a biological molecule associated with enzyme activity in a sample. The invention is applicable to detecting a microorganism associated with an enzyme in a sample such as water, food, soil, or a biologica... | 07/22/2008 |
| 7391942 | Long period grating sensor methods and apparatus The invention relates to optical sensors and systems and methods employing the sensors for detecting one or more compounds of interest in a test medium. In one embodiment an optical sensor comprising a long period grating and a solid phase microextraction (SPME) fil... | 06/24/2008 |
| 7335484 | Retinoid metabolizing protein Amino acid sequences and corresponding nucleic acid sequence of retinoid metabolizing protein found in human, mouse and zebrafish are described, as well as methods of using same. ... | 02/26/2008 |
| 7196169 | Isolated post-translationally modified mammalian proteins for monitoring and diagnosing muscle damage Isolated phosphorylated troponin I proteins useful in diagnosing and monitoring the phosphorylation state of injured muscle tissue are provided. Also provided are compounds, kits and methods for assessing the phosphorylation state of these troponin I proteins and mo... | 03/27/2007 |
| 7195890 | Methods and compositions for modulating proteins modified in preconditioning against ischemia/hypoxia Proteins modified by pharmacological preconditioning are provided. Compositions, methods and events for modulating these proteins and priming cells for preconditioning and inducing preconditioning in a cell, tissue or organ as well as methods for identifying new com... | 03/27/2007 |
| 7171972 | Passive back-flushing thermal energy system This invention provides a thermal energy system comprising a heat exchanger for transferring thermal energy between a source and a load, the heat exchanger having a primary side associated with the source, and a secondary side for conducting a fluid associated with ... | 02/06/2007 |
| 7162834 | Methods for enhancing plant growth using hydrogen gas This invention provides methods of enhancing plant growth or yield, comprising exposing soil to hydrogen gas (H2), and growing plants in the soil. The H2 gas employed can be generated by electrolysis of water, produced by H2 evolving... | 01/16/2007 |
| 7153692 | Diagnostic methods for determining susceptibility to convulsive conditions The present invention exploits the discovery that amounts of uracil and thymine metabolites, especially β-aminoisobutyric acid, in various bodily fluids, especially urine, are correlated with the occurrence of epilepsy when compared to matched control subjects. Ana... | 12/26/2006 |
| 7148352 | Method of inhibiting neurotrophin-receptor binding The present invention relates to compositions which inhibit the binding of nerve growth factor to the p75NTR common neurotrophin receptor and methods of use thereof. In one embodiment, the compound which inhibits binding of nerve growth factor to p75... | 12/12/2006 |
| 7143762 | Method and apparatus for solar collector with integral stagnation temperature control This invention relates to a method and apparatus for a solar collector having intergral control of the the maximum temperature that it can reach, thereby avoiding excessive stagnation temperatures in the collector. In one embodiment, a solar collector comprises a to... | 12/05/2006 |
| 7115661 | Methods and compositions for mitigating pain Methods and therapeutic compounds for treating pain, mitigating inflammation, effecting analgesia and/or effecting sedation in a subject are described. A subject is administered an effective amount of a therapeutic compound which is a nitrate ester. Novel pharmaceut... | 10/03/2006 |
| 7110265 | Non-isolated DC-DC converters with direct primary to load current DC—DC converters have high side and rectifier circuits, and output capacitor. High side circuit connects between input voltage and output voltage, and has primary winding and auxiliary section that operate transformer properly. Auxiliary may have switches or combi... | 09/19/2006 |
| 6995252 | PT32 sperm protein, sperm c-Yes, oocyte cytoplasmic c-Yes and uses thereof The perinuclear theca 32 (PT32) protein is disclosed and shown to interact with tyrosine kinase c-Yes. PT32, c-Yes, fragments thereof, and molecules that bind thereto can be used in methods of enhancing fertility, treating or diagnosing diminished fertility and abno... | 02/07/2006 |
| 6984393 | Biodegradable elastomer and method of preparing same This invention relates to thermally crosslinked and photo-crosslinked biodegradable and biocompatible elastomeric polymers. The elastomers can be used for biomedical devices such as needles, stents, catheters, scaffolds for tissue engineering, and implantable drug d... | 01/10/2006 |
| 6974417 | Ultrasound transducer array This invention relates to an ultrasonic transducer array for non-destructive imaging and inspection of materials, suitable for applications such as bio-medical imaging. According to the invention, the transducer has at least one electrode comprising an array of elec... | 12/13/2005 |
| 6930112 | Anti-epileptogenic agents Methods and compounds useful for the inhibition of convulsive disorders, including epilepsy, are disclosed. The methods and compounds of the invention inhibit or prevent ictogenesis and epileptogenesis. Methods for preparing the compounds of the invention are also d... | 08/16/2005 |
| 6861238 | Retinoid metabolizing protein Amino acid sequences and corresponding nucleic acid sequence of retinoid metabolizing protein found in human, mouse and zebrafish are described, as well as methods of using same. ... | 03/01/2005 |
| 6848212 | Methods for enhancing plant growth using hydrogen gas This invention provides methods of enhancing plant growth or yield, comprising exposing soil to hydrogen gas (H2), and growing plants in the soil. The H2 gas employed can be generated by electrolysis of water, produced by H2 evolving... | 02/01/2005 |
| 6840470 | Refiner force sensor This invention relates to a refiner force sensor for refiners used in the pulp and paper industry, to a refining apparatus, and to a method of measuring force acting on a refiner bar in a refiner. ... | 01/11/2005 |
| 6842548 | Optical loop ring-down The invention provides a method and apparatus for measuring one or more optical properties of a test medium, comprising providing an optical waveguide loop comprising a test medium, illuminating the optical waveguide loop with a plurality of light pulses, and detect... | 01/11/2005 |
| 6827091 | Passive back-flushing thermal energy system A thermal energy system including a heat exchanger for transferring thermal energy between a source and a load, the heat exchanger having a primary side associated with the source, and a secondary side for conducting a fluid associated with the load, wherein the sec... | 12/07/2004 |
| 6756407 | Method and compositions for the treatment or amelioration of female sexual dysfunction The present invention provide a method of treating sexual dysfunction in a female, including the vasculogenic symptoms of delayed vaginal engorgement, diminished vaginal lubrication, pain or discomfort with intercourse (dyspareunia), diminished vaginal sensation, di... | 06/29/2004 |
| 6747130 | Tenebrio antifreeze proteins A novel class of thermal hysteresis (antifreeze) proteins (THP) that have up to 100 times the specific activity of fish antifreeze proteins has been isolated and purified from the mealworm beetle, Tenebrio molitor. Internal sequencing of the proteins, leading... | 06/08/2004 |
| 6713527 | Anaesthetic bone cement The invention relates to surgical bone cement compositions and more particularly to bone cement compositions having aneasthetic properties, and to methods for producing analgesia. ... | 03/30/2004 |
| 6710066 | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exo... | 03/23/2004 |
| 6677374 | Nitrate esters and methods of making same Compounds and methods for mitigating neurodegeneration, effecting neuroprotection and/or effecting cognition enhancement in a subject are described. Neurological or cognitive conditions are treated by administering to a subject an effective amount of a th... | 01/13/2004 |
| 6635648 | Combination therapy using sympathetic nervous system antagonists and endothelin antagonists Methods are provided for preventing or inhibiting adverse cardiovascular effects associated with administration of a sympathetic nervous system antagonist in a subject, in which a subject in need thereof is administered a sympathetic nervous system antago... | 10/21/2003 |
| 6632328 | Method for bleaching mechanical pulp with hydrogen peroxide and an alkaline earth metal carbonate A method for bleaching unbleached softwood or hardwood pulps using hydrogen peroxide without added alkali for activation is described. The aqueous hydrogen peroxide solution contains an alkaline earth metal carbonate, preferably magnesium carbonate and ca... | 10/14/2003 |
| 6610652 | Microdose therapy Methods for treating vascular conditions associated with localized imbalance in vascular tone, which are hypothesized to be largely due to elevated endothelin (ET) are provided. The methods involve administration of nitric oxide (NO), agents which are abl... | 08/26/2003 |
| 6586391 | Method of ameliorating erectile dysfunction The mechanism of hypertension following acute NO synthase blockage is via endothelin-mediated vasoconstriction. Thus, NO appears to inhibit endothelin activity by blocking its expression and not as a chronic direct acting vasodilator. Administration of an... | 07/01/2003 |
| 6562836 | Methods and compounds for inhibiting amyloid deposits Methods and compositions which are useful in the treatment of amyloidosis. In particular, methods and compositions are provided for inhibiting, preventing and treating amyloid deposition, e.g., in pancreatic islets, wherein the amyloidotic deposits are is... | 05/13/2003 |
| 6516277 | Method for determining multi-dimensional topology This invention relates to methods and apparatus for determining the multi-dimensional topology of a substance (system) within a volume (space). A method according to a preferred embodiment of the invention comprises the steps of: acquiring a set of relati... | 02/04/2003 |
| 6500569 | Luminescent compounds and methods of making and using same Heterocyclic organoaluminum and organoboron coordination complexes that are photoluminescent and electroluminescent, emitting intense blue light. Methods of synthesizing such compounds, methods of producing photoluminescence and electroluminescence, metho... | 12/31/2002 |
| 6492380 | Method of inhibiting neurotrophin-receptor binding The present invention relates to compositions which inhibit the binding of nerve growth factor to the p75NTR common neurotrophin receptor and methods of use thereof. In one embodiment, the compound which inhibits binding of nerve growth factor ... | 12/10/2002 |
| 6493637 | Coincidence detection method, products and apparatus A method and system for detecting coincidences in a data set of objects, where each object has a number of attributes. Iteratively, equally-sized subsets of the data set of sampled, and coincidences (co-occurrences of a plurality of attribute values in on... | 12/10/2002 |
| 6468990 | Method of inhibiting binding of nerve growth factor to p75 NTR receptor The present invention relates to compositions which inhibit the binding of nerve growth factor to the p75NTR common neurotrophin receptor and methods of use thereof. In one embodiment, the compound which inhibits binding of nerve growth factor ... | 10/22/2002 |
