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Assignee: Quark Biotech, Inc.


Location: Cleveland, OH
No. of patents: 6

NumberTitleIssue Date
7202211Methods of preventing or treating brain ischemia or brain injury
The present invention relates to use of Narp inhibitor in order to promote or enhance recovery from ischemic events, particularly focal ischemia of the central nervous system, as well as for preventing or diminishing chronic degenerative changes. ...
04/10/2007
6833237Genes involved in stroke response and/or regulated by FK506, proteins encoded thereby, and methods of use
Genes and the proteins encoded thereby that are involved in stroke response and/or are regulated by FK506 are disclosed. These genes were discovered using in vivo or in vitro stroke models by determining which genes were differentially upregulated or downregulated u...
12/21/2004
6696454Inhibitors of spermidine synthase for the treatment of osteoarthritis and cartilage rehabilitation
This invention provides a method for the treatment of a subject in need of treatment for osteoarthritis comprising administering to said subject an amount of an inhibitor of spermidine biosynthesis sufficient to effect a substantial inhibition of spermidi...
02/24/2004
6544741Sequence specific and sequence non-specific methods and materials for cDNA normalization and subtraction
This invention provides methods for constructing a normalized cDNA library, constructing a low copy gene library, preparing a probe from a biological sample and a kit for constructing a normalized cDNA library....
04/08/2003
6528262Method for enrichment of natural antisense messenger RNA
A method for enrichment of natural antisense mRNA which involves hybridization of cDNA obtained from sense RNA with cDNA obtained from antisense RNA, followed by DNA polymerase treatment of the sense-antisense hybrid DNA molecule. A natural antisense libr...
03/04/2003
6468749Sequence-dependent gene sorting techniques
This invention provides a method of sorting genes comprising: (1) preparing ds cDNA molecules from mRNA molecules (2) digesting the ds cDNA molecules (3) ligating to the digested cDNA molecules a set of dsDNA oligonucleotide adaptors; (4) amplifying the l...
10/22/2002
 
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