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| Number | Title | Issue Date |
| 6881841 | Dibenzosuberanyl piperazine derivatives and drug-resistance overcoming agents containing the derivatives Dibenzosuberanyl piperazine derivatives represented by the following formula (I): wherein R represents an aliphatic hydrocarbon group, which may contain one or more heteroatom-containing substituent groups and may preferably cont... | 04/19/2005 |
| 6743925 | Nitroimidazole derivative and diagnostic imaging agent containing the same A nitroimidazole derivative represented by the following formula (1): [wherein R1 represents a hydrogen atom or a C1-C4 alkanoyl group; and X represents a fluorine atom or an isotope thereof], and a diagnostic imaging ag... | 06/01/2004 |
| 7425427 | Method for staining corneocytes, method for preparing corneocytes specimen and skin analysis system A method for preparing corneocytes specimen, which comprises stripping off corneocytes from the surface of a skin using an adhesive material, staining the corneocytes in a solution of stain in solvent containing a water-miscible organic solvent, and mounting the sta... | 09/16/2008 |
| 7421105 | Method for staining corneocytes, method for preparing corneocytes specimen and skin analysis system A method for preparing corneocites specimen, which comprises stripping off corneocites from the surface of a skin using an adhesive material, staining the corneocites in a solution of stain in solvent containing a water-miscible organic solvent, and mounting the sta... | 09/02/2008 |
| 7197359 | Compositions for electroporation The present invention relates to compositions for electroporation which are useful in elevating percutaneous absorbability of drugs, etc. By controlling electrolyte concentration of compositions for electroporation so as to make an osmotic pressure of the compositio... | 03/27/2007 |
| 7141601 | Dendrite elongation inhibitor for melanocyte and skin preparation for external use containing the same The present invention relates to a dendrite elongation inhibitor for melanocytes consisting of a compound represented by the following general formula (1): and/or a salt thereof, | 11/28/2006 |
| 7089053 | Compositions for drug administration by electroporation The present invention relates to compositions for electroporation which are useful in elevating a percutaneous absorbability of drugs, etc. By adding polyhydric alcohols to compositions for electroporation, the percutaneous absorbability of drugs is elevated. ... | 08/08/2006 |
| 7052866 | Method for evaluating the efficacy of an antifungal agent A correct viable cell number of a microorganism in a biological tissue is measured by cultivating a fragment of the biological tissue such as skin infected with the microorganism and administered with an antimicrobial agent, in a medium containing a phospholipid, a ... | 05/30/2006 |
| 6929927 | Method of evaluating antifungal agent A correct viable cell number of a microorganism in a biological tissue is measured by cultivating a fragment of the biological tissue such as skin infected with the microorganism and administered with an antimicrobial agent, in a medium containing a phospholipid, a ... | 08/16/2005 |
| 6878548 | Composition for use in electroporation The present invention is a composition for percutaneous administration suitable for electroporation. Percutaneous absorption of a drug and so forth in a composition for electroporation can be promoted by adding alkaline earth metal ions to the composition. ... | 04/12/2005 |
| 6797711 | Benzofuran derivatives and pharmaceutical compositions containing the same Benzofuran derivatives represented by formula (I) or salts thereof: (wherein R1 represents a phenyl group or a hydrogen atom; k is 0 or 1; each of m, n, o, p, and q is an integer of 0 to 5; and each of R2... | 09/28/2004 |
| 6786100 | Device for measuring physical properties of elastic bodies A device for measuring mechanical properties of an elastic body, comprising: at least two contacts adapted to contact a surface of an elastic body to be measured, at least one of said contacts being a movable contact; a drive section for moving said mo... | 09/07/2004 |
| 6740315 | Coated powder and cosmetic prepared by blending the same Coated powder is obtained by applying a material having a refractive index of 1.9 to 3.1 to powder having a refractive index of 1.3 to 1.8 as a core and further applying a material having a refractive index of 1.3 to 1.8 to the coated core. When this powder is used ... | 05/25/2004 |
| 6721595 | Percutaneous absorption promoters for electroporation The present invention relates to percutaneous sorbefacients for electroporation consisting of monoterpene and being useful in elevating percutaneous absorbability of drugs, etc. By adding these percutaneous sorbefacients to compositions for electroporation, the perc... | 04/13/2004 |
| 6703468 | Compound, polymer prepared from the compound, and composition comprising the polymer A composition comprising a polymer containing a compound represented by Formula (1) or a salt thereof as a constituent monomer, or a polymer containing a structure represented by Formula (9) as a partial structure is used for protecting or improving skin.... | 03/09/2004 |
| 6586633 | Amine derivatives The present invention relates to amine derivatives represented by formula (1) or salts thereof. ##STR1## R3 represents C1-C3 alkyl, hydroxylated C1-C5 alkyl, C1-C5 acyl; C2-C5 alkenyl, or a halogen atom; and k, l, and m are each an integer of 1... | 07/01/2003 |
| 6495524 | Benzo[b]pyran derivatives useful as external agents for the skin To provide an external agent for thee skin that not only exhibits excellent effects of prevention and amelioration of skin pigmentation but also has no fear of giving adverse influences to the skin and can be used safely, there is added to an external age... | 12/17/2002 |
| 6475748 | Method for differentiating human peripheral blood granulocytes Disclosed is a method for differentiating human peripheral blood granulocytes which comprises cultivating the granulocytes in the presence of an interferon and acting an immune complex on said granulocytes in the presence of a chemiluminescent substance, ... | 11/05/2002 |
| 6462003 | Transparent solid soap and transparent soap material A transparent solid soap or transparent soap material which comprises mainly of a salt of the fatty acid, is obtained by saponifying fatty acid or animal/vegetable oil with alkali, wherein 1) the alkali is sodium hydroxide and organic amine, and a molar ratio ... | 10/08/2002 |
| 6340677 | Method of evaluation of skin conditioning-ameliorating agents and method of producing compositions for topical application to skin An object of the present invention is to provide a means of appropriately evaluating a skin conditioning-ameliorating agent for ameliorating bad skin conditions or preventing the skin conditions from getting worse and a composition for topical application... | 01/22/2002 |
| 6338854 | Photoaging skin-care preparation and method of treating wrinkled skin Photoaging skin care preparations and methods of treating wrinkled skin are described. The photoaging skin care preparations contain at least one triterpenoid derivative which is a substituted form of ursolinic, oleanolic, or betulic acid. The photoaging ... | 01/15/2002 |
| 6329399 | Antifungal amine derivatives and processing for producing the same Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below and salts thereof are provided. ##STR1## [in the formula (1, R1 represents a C1-5 alkyl group which may be halogenated, R2 | 12/11/2001 |
| 6329382 | Pyrrolo[3,2-e]pyrazolo[1,5-a]pyrimidine remedies/preventives for respiratory diseases The invention relates to a therapeutic and preventive medicament for respiratory diseases, comprising, as an active ingredient, a compound represented by the general formula (1): ##STR1## wherein R1 represents a linear, branched or cyclic alkyl... | 12/11/2001 |
| 6207711 | Photoaging inhibitor and skin-care preparation In order to obtain photoaging inhibitor comprising a triterpenoid compound having high safety and excellent photoaging inhibiting effect, a photoaging inhibitor comprises one or more compounds selected from triterpenoid derivatives and salts thereof, wher... | 03/27/2001 |
| 6136863 | Antifungal agents This invention relates to compounds represented by the following formula (1): ##STR1## wherein R1 represents a substituted or unsubstituted phenyl group, R2 represents a substituted or unsubstituted phenylene group, R3 | 10/24/2000 |
| 6100280 | Narcotic antagonist A narcotic antagonist comprising, as its active component, a compound represented by the following formula (1) or a physiologically acceptable salt thereof: wherein each of R1 and R2, which may be identical to or different from each ... | 08/08/2000 |
| 6057330 | Pyrrolopyrazolopyrimidine compound and medicine comprising the same as active ingredient The invention relates to compounds represented by the following general formula (1): ##STR1## wherein R1 represents an alkyl group, R2 represents an amino group, alkyl group or the like, and R3 represents a nitro grou... | 05/02/2000 |
| 6015925 | Antifungal agents This invention relates to compounds represented by the following formula (1): ##STR1## wherein R1 represents a substituted or unsubstituted aromatic hydrocarbon group having 6 to 18 carbon atoms, R2 represents a hydrogen at... | 01/18/2000 |
| 5952308 | Mineral absorption promoting agent A mineral absorption promoting agent containing oligouronic acid, e. g. oligogalacturonic acid or oligomannuronic acid degree of polymerization (n)=1 to 9! is described. Since this oligouronic acid polymerization degree (n)=1 to 9! forms a complex wit... | 09/14/1999 |
| 5942515 | Pyrrolopyrazolopyrimidine compound and medicine comprising the same as active ingredient The invention relates to compounds represented by the following general formula (1): ##STR1## wherein R1 represents an alkyl group, R2 represents an amino group, alkyl group or the like, and R3 represents a nitro grou... | 08/24/1999 |
| 5929104 | Method for inducing apoptosis of cancer cell Disclosed herein are a method for inducing apoptosis of cancer cells, which comprises administering an effective amount of a 2-nitroimidazole derivative represented by the general formula (1): ##STR1## wherein R represents an alkyl, alkenyl or alkyny... | 07/27/1999 |
| 5888879 | Method for evaluating make-up cosmetic product and powder composition A make-up cosmetic product, which enhances the appearance of complexion, is evaluated by irradiating lights having a wavelength range of visible light onto a surface on which the make-up cosmetic product is applied, from at least two directions with diffe... | 03/30/1999 |
| 5843674 | Anti-human tyrosinase monoclonal antibody A mammal is immunized by using an antigen of a peptide having an amino acid sequence existing in a region having low homology to amino acid sequences of tyrosinase-related proteins but included in an amino acid sequence of human tyrosinase, and then the s... | 12/01/1998 |
| 5747493 | Dopamine re-uptake inhibitor A method for inhibiting dopamine re-uptake and treating Parkinson's disease is disclosed comprising administering a compound represented by formula (1) or a physiologically acceptable salt thereof as the active ingredient: ##STR1## wherein R1 | 05/05/1998 |
| 5532380 | R,R,S,S-2-nitroimidazole derivatives High purity 2-nitroimidazole derivatives having excellent radiosensitivity and high safety and useful as a drug to be used along with radiotherapy of various cancers can be prepared at a high yield from inexpensive diester of tartaric acid according to th... | 07/02/1996 |
| 5391552 | Diphenylpiperazine derivative and drug for circulatory organ containing the same A diphenylpiperazine derivative represented by general formula (1), salt thereof, and drug for the circulatory organs containing the same as the active ingredient: ##STR1## wherein R1 and R2 may be the same or different from eac... | 02/21/1995 |
| 5310749 | Antiprotozoal composition containing a 2-nitroimidazole derivative and method thereof Disclosed herein is an antiprotozoal composition containing a 2-nitroimidazole derivative as its active component. This drug is especially useful against Trypanosoma cruzi. Process for the preparation is also disclosed.... | 05/10/1994 |
| 5270330 | 2-nitroimidazole derivative, production thereof, and radiosensitizer containing the same as active ingredient The present invention relates to a 2-nitroimidazole derivative represented by the following general formula (I): ##STR1## wherein R1, R2 and R3 may be the same or different from each other and mean individually a hydr... | 12/14/1993 |
