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...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.

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Assignee: Pierre Fabre Dermo-Cosmetique


Location: Boulogne-Billancourt, FR
No. of patents: 11

NumberTitleIssue Date
8158811Unsaturated fatty hydroxy acid derivatives and the dermocosmetologic use thereof
The invention relates to unsaturated fatty hydroxy acid derivatives of formula (I), wherein Rn is independent from each other H or linear or branched alkyl group which contain from 1 to 6 carbon atoms and which are possibly substituted by a halogen atom, ...
04/17/2012
8053573Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof
The invention relates to the use of 5,6-diphenyl-1,2,4-triazinic compounds of general formula (I), wherein cycle penetrating bonds display an ortho, meta or para indifferent substitution position, identical or different R1 and R2 represent a hydrogen, fluoride, chlo...
11/08/2011
8007836extract used in pharmaceutical preparations and cosmetic compositions
The invention relates to a Cleome spinosa extract used as an active ingredient in a cosmetic or pharmaceutical composition for extending the growth of hair follicles. ...
08/30/2011
7999096Anti-myosin Va siRNA and skin depigmentation
The present invention relates to novel isolated siRNAs comprising a sense RNA strand and a complementary antisense RNA strand which together form an RNA duplex, characterized in that the sense RNA strand comprises a sequence which has at most one nucleotide that is ...
08/16/2011
7928254Method for preparing unsaturated fatty hydroxyacids
The invention concerns a method for preparing a compound of formula (I), wherein: R3 and R1 represent in particular H and n is greater than 4, said preparation method including performing a Wittig-Horner reaction with a phosphonate on a lactol,...
04/19/2011
78165205,6-diphenyl-1,2,4-triazinic dimeric derivatives and the use thereof in the form of sun-protective agents
The invention relates to 5,6-diphenyl-1,2,4-triazinic compounds of general formula (I), wherein identical or different R1, R2, R3 and R4 represent a hydrogen, fluoride, chloride or bromine atom, C1 to C12 linear or branched alkyl, C1 A C18 linear or branched hydroxy...
10/19/2010
7666847Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders
The invention relates to a medicament comprising at least one reducing alkyl-sugar monomer having a hydroxyl function which is substituted by an alkoxy radical at C2-C40, said medicament being preferably intended to regulate inflammatory mechan...
02/23/2010
7192613bulb absolutes and therapeutic or cosmetic uses
The invention concerns Allium sativum bulb absolutes, compositions containing them, and uses thereof for therapeutic purposes—in particular in the treatment of obesity—and for cosmetic purposes—in particular for the treatment of the skin, of cellulite a...
03/20/2007
6818657Bioprecursors of a retinoic derivative and pharmaceutical and/or cosmetic compositions
The present invention relates to a ternary glucosyl complex which is a bioprecursor of at least one retinoic active ingredient for percutaneous application, having formula (I), wherein E represents a linear hydrocarbon spacer group that is branched or cyclized and h...
11/16/2004
6569906Composition containing a precursor capable of being hydrolysed by glucocerebrosidase
The invention concerns a composition capable of being hydrolyzed by a cutaneous enzyme, glucocerebrosidase. The active precursor is advantageously a gluco-conjugate derived from phenol whereof the two ଱ carbons are free. The invention also concerns ...
05/27/2003
6319392Coal tar extract with reduced aromatic hydrocarbon content, method for obtaining same and dermatological and cosmetic compositions
The invention concerns a coal tar extract with reduced polycyclic aromatic hydrocarbon and benzo(a)pyrene content and a method for obtaining same using two sequentially linked distillation systems. The invention also concerns cosmetic and dermatological p...
11/20/2001
 
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