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| Number | Title | Issue Date |
| 8039648 | Compounds used as dyes comperable to Alexa Fluor 350 dyes Compounds used as dyes comparable to Alexa Fluor 350 dyes. The inventive compounds have high fluorescence quantum yield and high photostability. The dyes facilitate analysis of biological structures with enhanced sensitivity and selectivity. ... | 10/18/2011 |
| 8007998 | Polymerized conjugates for biological applications Polymerized conjugates of at least two proteins that have increased sensitivity for detecting proteins in biological assays such as gels and blots, and methods of preparing the conjugates, and a protein assay detection kit using the conjugates. In one embodiment, pr... | 08/30/2011 |
| 8007668 | Dialysis device with access port A device for dialysis of a sample includes a sample chamber formed by a gasket and dialysis membranes affixed to each side of the gasket in facing relationship. A housing supports the dialysis membranes and gasket. An air chamber causes the device to float in a gene... | 08/30/2011 |
| 7960519 | Extraction of cellular components with fatty acid derivatives A method of treating biologic material with a composition containing at least one fatty acid derivative and/or at least one fatty alcohol, a buffer, and a salt to result in protein partitioning into an aqueous phase and an organic phase. The protein may be a membran... | 06/14/2011 |
| 7947506 | Protein detection and quantitation using hydroxyquinolone dyes A hydroxyquinolone compound formulated as a fluorescent dye for protein detection, assay, quantitation, etc. The hydroxyquinolone compound may be modified, for example, by adding or removing sulfate groups, changing hydrocarbon chain lengths, etc. to result in more ... | 05/24/2011 |
| 7745645 | Sulfonamide derivatives of xanthene compounds Compounds having the general of formula I and/or formula II ... | 06/29/2010 |
| 7745153 | Pyrocatechol violet-metal protein assay A method for protein determination utilizing a pyrocatechol violet-metal complex, a composition used in the protein determination assay, and a kit. ... | 06/29/2010 |
| 7553869 | Protein probe compounds, compositions, and methods Coumarine/chinolone and Martina-type compounds, compositions, and method of using the compounds and compositions for protein detection, assay, quantitation, etc. are disclosed. The composition, also referred to as a dye, has enhanced sensitivity over commercially av... | 06/30/2009 |
| 7498140 | Direct detection of biomolecules in a gel A method for detecting a target biomolecule directly in a polyacrylamide gel in which it has been separated from other substances. Prior to binding the target to a probe and while the target biomolecule remains in the gel, the gel is immersed in a water miscible aqu... | 03/03/2009 |
| 7432070 | Homogenous assay for enzymatic activity An assay is disclosed for measuring activity of enzymes, such as kinases, phosphatases, and proteases. Measurements of enzymatic activity are accomplished in a homogenous assay format utilizing a fluorescence quenching technique employing paramagnetic metal ions. | 10/07/2008 |
| 7407800 | Method for the isolation of intact mitochondria from cells Intact mitochondria is isolated from cells by swelling the cells, lysing the swollen cells using a mild detergent such as CHAPS to release the mitochondria, and then recovering the mitochondria. ... | 08/05/2008 |
| 7306928 | Homogenous assay for enzymatic activity An assay is disclosed for measuring activity of enzymes, such as kinases, phosphatases, and proteases. Measurements of enzymatic activity are accomplished in a homogenous assay format utilizing a fluorescence quenching technique employing paramagnetic metal ions. | 12/11/2007 |
| 7118804 | Pelletized chromotography media A method of using a pellet composed of an aggregate of distinct beads of a chromatography media. The pellet is coherent and capable of being rapidly hydrated on addition of water to form a gel wherein said beads are swollen and substantially uniformly dispersed in t... | 10/10/2006 |
| 7112411 | Direct detection of biomolecules in polyacrylamide gel improvement comprising shrinking and rehydrating of gel prior to labeling An improved method for detecting a target biomolecule directly in a polyacrylamide gel in which it has been separated from other substances. The improvement resides in, prior to binding the target to a probe and while the target biomolecule remains in the gel, (1) i... | 09/26/2006 |
| 7056440 | Dialysis device with air chamber A device for the dialysis of a sample includes a hermetically sealed sample chamber formed by a gasket with dialysis membranes affixed to each side in facing relationship. The gasket is impermeable to the sample being dialyzed, but is penetrable and reusable such th... | 06/06/2006 |
| D503612 | Packaging container | 04/05/2005 |
| 6852503 | Compositions and methods for utilizing mixed substrate solutions of luminols and dioxetanes A dual enzyme chemiluminescent substrate formulation useful for the independent or simultaneous analysis of the enzymes is disclosed, the formulation includes, as one substrate component, dihydrophthalazinedione, such as luminol or isoluminol, and a peroxide source ... | 02/08/2005 |
| 6709743 | Pelletized chromatography media of agarose, dextran or acrylamide/azlactone copolymer A pellet composed of an aggregate of distinct beads of a chromatography media. The pellet is coherent and capable of being rapidly hydrated on addition of water to form a gel wherein said beads are swollen and substantially uniformly dispersed in the water phase. | 03/23/2004 |
| 6670159 | Preparing monomeric metal ion chelator containing diacetyl glycine group linked to proteinaceous molecule A precursor for the construction of chelated metal conjugates which demonstrate improved assay performance and utility in minimizing non-specific binding while maintaining specificity for target molecules is disclosed. The precursor has tridentate functio... | 12/30/2003 |
| 6638728 | Coated surfaces with high capacity for capturing target molecules New protein coated surfaces, which have a high capacity for capturing target molecules, thus yielding assays with enhanced sensitivity, are disclosed. Surfaces prepared according to the present invention contain a coating consisting essentially of strepta... | 10/28/2003 |
| 6613548 | Fusion products containing insoluble proteinaceous tag A process is disclosed for the preparation of a recombinantly expressed fusion product comprised of a proteinaceous tag and a soluble protein of interest and the separation of the fusion product from the host cell in which it is expressed. The tag and in ... | 09/02/2003 |
