Did You Know...
...that power steering was invented by independent inventor Francis W. Davis? As chief engineer in the 1920s of the truck division of the Pierce Arrow Motor Car Company, he saw how hard it was to steer heavy vehicles. So that he would be able to keep the profits from his future invention, Davis left his job, rented a small engineering shop in Waltham, Mass., and developed a hydraulic power steering system that led to power steering.
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| Number | Title | Issue Date |
| 7354943 | Statine derivatives for the treatment of Alzheimer's disease The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment ... | 04/08/2008 |
| 7317011 | Method of treating peripheral neuropathy Disclosed herein are methods of treating an individual suffering from peripheral neuropathy. The methods generally include administration of a therapeutic amount of optically pure (S,S) reboxetine, or a pharmaceutically acceptable salt thereof. Embodiments of these ... | 01/08/2008 |
| 7214715 | Compounds to treat Alzheimer's disease The present invention is substituted amines of formula (X) and of the formula (X′) useful in treating Alzheimer's disease and other similar diseases. ... | 05/08/2007 |
| 7087784 | Process to prepare oxazolidinones The present invention relates to a one-step process to prepare pharmacologically active 2-oxo-5-oxazolidinylmethylacetamides. ... | 08/08/2006 |
| 7037695 | Methods of assessing wolframin protein activity The present invention relates to a method of assaying modulators of the interaction between Wolframin protein and its identified cellular binding partner. ... | 05/02/2006 |
| 6964965 | Substituted pyrazine derivatives The present invention provides substituted pyrazine derivatives of Formula I, that are CRF1 receptor antagonists, including human CRF1 receptors. This invention also relates to use of compounds of... | 11/15/2005 |
| 6951950 | Quaternary ammonium compounds The invention features quaternary ammonium compounds of formula I, described herein, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious rhinitis. ... | 10/04/2005 |
| 6946486 | Quaternary ammonium compounds The invention features quaternary ammonium compounds of formula I, described herein, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious rhinitis. ... | 09/20/2005 |
| 6916914 | Purification of somatotropin from transformed microorganisms This invention discloses a commercially advantageous process for extraction and purification of protein from microorganisms. The initial steps of the process are useful for purifying many insoluble proteins while later steps are designed to renature denatured somato... | 07/12/2005 |
| 6878730 | Quaternary ammonium compounds The invention features quaternary ammonium compounds of formula I, described herein, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious rhinitis. ... | 04/12/2005 |
| 6864290 | Statine derivatives for the treatment of Alzheimer's disease The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treat... | 03/08/2005 |
| 6841557 | Compounds for the treatment of addictive disorders The treatment of addictive disorders, psychoactive substance use disorders, intoxication disorders, inhalation disorders, alcohol addiction, tobacco addiction, and nicotine addiction using a heterocyclic amine, a phenylazacycloalkane, a cabergoline, or an aromatic b... | 01/11/2005 |
| 6831081 | 4-Oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents The present invention provides a compound of formula as described herein, which are useful as antiviral agents, in particular, as agents against viruses of the herpes family. ... | 12/14/2004 |
| 6673793 | Oxazinoquinolones useful for the treatment of viral infections The present invention provides a compound of formula I ##STR1## which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.... | 01/06/2004 |
| 6624160 | 4-oxo-1,4-dihydro-3-cinnolinecarboxamides as antiviral agents This invention provides compounds of formula I; ##STR1## which are useful as antiviral agents.... | 09/23/2003 |
| 6615844 | Hair thinning measurement device A self-analysis hair density measuring device comprises a housing body with a calibrated gauge element movably affixed to one side of the housing body. There are at least two or preferably three movable pronged tines extending from within the proximal end... | 09/09/2003 |
| 6573293 | Pyrrole substituted 2-indolinone protein kinase inhibitors The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinas... | 06/03/2003 |
| 6387896 | Bicyclic oxazolidinones as antibacterial agents The present invention provides compounds of formula I useful as antimicrobial agents ##STR1## wherein W, X, Y, R1, R2 and n are as defined in thereof.... | 05/14/2002 |
| 6387900 | 3(5)-ureido-pyrazole derivatives process for their preparation and their use as antitumor agents 3-ureido-pyrazole derivatives represented by formula (I): ##STR1## where R, R1 and R2 are as described herein, or pharmnaceutically acceptable salts thereof; are useful, for example, for the treatment of cancer, cell proliferative di... | 05/14/2002 |
| 6218418 | 3(5)-amino-pyrazole derivatives, process for their preparation and their use as antitumor agents Compounds which are 3-amino-pyrazole derivatives represented by formula (I): ##STR1## where R is a C3 -C6 cycloalkyl group, which may optionally be substituted by a straight or branched C1 -C6 alkyl group, and R... | 04/17/2001 |
| 6087340 | Injectable ready-to-use solutions containing an antitumor anthracycline glycoside A sealed glass container containing therein a stable, injectable, sterile, pyrogen-free doxorubicin anti-tumor composition in a solution which consists essentially of a physiologically acceptable salt of doxorubicin dissolved in a physiologically acceptab... | 07/11/2000 |
| 6051716 | Phenyloxazolidinones having a c-c bond to 4-8 membered heterocyclic rings A process for preparing a compound of the formula I: ##STR1## or pharmaceutical acceptable salts thereof wherein X is --NR,--, --S(O)g --, or --O--; R1 is --H, C1-6 alkyl optionally substituted with one or more --OH, ... | 04/18/2000 |
| 5910504 | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials A hetero-aromatic (Q) substituted phenyloxazolidinone antimicrobial of Formula (I) wherein Q is a 5-member hetero-aromatic having from one to four nitrogen atoms or alternatively a benzoannulated 5-member hetero-aromatic having from one to four nitrogen a... | 06/08/1999 |
| 5823146 | Animal restraining device An animal restraining device including a restraining litter and a support frame. The frame supports the litter thereon and has features which facilitate an adjusting of the width between support members of the litter and an adjusting of the height of the ... | 10/20/1998 |
