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| Number | Title | Issue Date |
| 7232894 | Method for the production of recombinant peptides with a low amount of trisulfides Methods for the production of recombinant peptides comprise fermenting cells to produce recombinant peptides. A metal salt is added to a concentrate of the fermented cells after the fermentation step, prior to peptide isolation, and the pH of the cell concentrate af... | 06/19/2007 |
| 7229965 | Use of growth hormone in low dose The invention relates to treatment of patients in need of increasing insulin sensitivity by administration of growth hormone or analogues thereof, preferably human growth hormone, in a low dose and the use of growth hormone or analogues thereof, preferably human gro... | 06/12/2007 |
| 7164133 | Delivery device and method for its operation A system of marked medical containers comprises at least two containers having different properties in at least one respect, and at least one machine-readable marking on each of the containers, each marking being designed to allow discrimination between the differen... | 01/16/2007 |
| 7122515 | Methods for treating a patient having Metabolic Syndrome A method for treating a patient having Metabolic Syndrome comprising Primary Insulin Resistance and exhibiting lipoprotein aberrations or hypertension comprises administering to said patient human growth hormone or a functional analog thereof in an amount effective ... | 10/17/2006 |
| 7104971 | Medical device The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a sto... | 09/12/2006 |
| 6911217 | Controlled release bead, a method of producing the same and multiple unit formulation comprising it A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble polymer; (iii) a second layer covering the first layer and containing an a... | 06/28/2005 |
| 6891025 | Modified cytokine receptor protein A modified extracellular domain of a cytokine receptor is capable of being crystallized without being complexed to a ligand molecule. The receptor preferably is a homo- or heterodemeric receptor having at least one molecule segment which contributes to a disorder st... | 05/10/2005 |
| 6858846 | Delivery device and method for its operation Provided is a method for operating a preparation delivery device wherein the device comprises a) a container for the preparation having, or being prepared for the arrangement of, an opening, b) a mechanism operable to deliver at least part of the preparation in the ... | 02/22/2005 |
| 6846800 | Method for treating a patient having metabolic syndrome Methods for treating a patient for insulin resistance to decrease the insulin resistance in a patient having Metabolic Syndrome comprising Primary Insulin Resistance and abdominal/visceral obesity comprise administering to the patient growth hormone or a functional ... | 01/25/2005 |
| 6807797 | Prefilled ampoules and manufacture thereof A syringe type ampoule having a) a barrel with a front end and a rear end defining an axis therebetween, the barrel having substantially constant cross-section between the front end and the rear end, at least the front end ending in an opening, b) a sealer attached ... | 10/26/2004 |
| 6790998 | Phenyl inden-1-one compounds The invention relates to a process for the enantioselective preparation of tolterodine and analogues and salts thereof comprises the steps of: a) enantioselectively reducing the carbonyl function in a compound of formula (II): | 09/14/2004 |
| 6770295 | Therapeutic formulation for administering tolterodine with controlled release The present invention is drawn to a method of treating an unstable or overactive urinary bladder by treating the patient with tolterodine or a tolterodine-related compound, or pharmaceutically acceptable salt thereof, with a controlled release formulation that maint... | 08/03/2004 |
| 6767994 | Process for purifying a compound The present invention relates to a process for purifying a hydrophobic or amphiphilic compound, by first mixing a starting material containing the hydrophobic or amphiphilic compound with a first polymeric material, water and at least one of a second polymeric mater... | 07/27/2004 |
| 6758837 | Liquid delivery device and method of use thereof A device and use method for ejecting a liquid stream towards an eye, the stream moving from a proximal position towards a distal position, the device comprising a) a housing, b) a container for the liquid, c) at least one opening arranged for ejection of the stream ... | 07/06/2004 |
| 6740062 | Medical device The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a sto... | 05/25/2004 |
| 6730066 | Liquid delivery container Pressurisable container for storing and ejecting liquid, the container comprising a) a front wall having or surrounding a cavity corresponding to the form of an open vessel, b) an opening in the front wall adapted for ejection of the liquid from the container, said ... | 05/04/2004 |
| 6709416 | Arrangement in electronically controlled injection devices In an electronically controlled injection device for the administering of one or more injections from an injection cartridge, the readying of the device for administrating and the subsequent administering therefrom are controlled by an electronic control unit. This ... | 03/23/2004 |
| 6696414 | Use of growth hormone in low dose The invention relates to treatment of patients in need of increasing insulin sensitivity by administration of growth hormone or analogues thereof, preferably human growth hormone, in a low dose and the use of growth hormone or analogues thereof, preferabl... | 02/24/2004 |
| 6689101 | Medical arrangement An injector device for delivery of liquid from a high pressure, the device comprising a housing, a pressure chamber 2 comprising a pressure barrel 4 for accommodation of at least one piston therein and having a front end opening 6 for ejection of the liqu... | 02/10/2004 |
| 6689916 | Phenyl propenone compounds The invention relates to a process for the enantioselective preparation of tolterodine and analogues and salts thereof comprises the steps of: a) enantioselectively reducing the carbonyl function in a compound of formula (II): ##STR1## wherein R1 | 02/10/2004 |
| 6680181 | Production of peptides The invention relates to a method for the production of recombinant peptides by fed-batch cultivation of a microorganism in a bioreactor containing a medium comprising organic carbon source, nitrogen source and mineral salts. The cultivation is carried ou... | 01/20/2004 |
| 6664534 | Tilt sensing device and method for its operation A tilt sensing device and method for its operation, the device being of the type comprising a) a housing, b) a radiation transmitter and a radiation receiver arranged in or at the housing to form a beam path therebetween, c) a radiation obstructing or def... | 12/16/2003 |
| 6634076 | Structure and method for joining parts The invention relates to an article of manufacture comprising a partial or complete tubular primary part defining a tube axis and having an at least partially curved circumferential wall at least partially encircling the axis; said wall comprising a joint... | 10/21/2003 |
| 6630162 | Pharmaceutical formulation and its use The invention relates to a pharmaceutical formulation containing tolterodine or a tolterodine-related compound, or a pharmacologically acceptable salt thereof, as active ingredient, in which the formulation exhibits a controlled in vitro release of the ac... | 10/07/2003 |
| 6620428 | Transdermally administered acetylcysteine as mucolytic agent Device for transdermal administration of N-Acetyl-L-cysteine, optionally encompassing salts, prodrugs and metabolites thereof, optionally together with pharmaceutically acceptable carrier(s) to a human being or an animal in order to achieve a mucolytic ef... | 09/16/2003 |
| 6605706 | Method for producing a correctly folded, biological active recombinant protein Methods for producing correctly folded biological active recombinant protein or polypeptide comprise the steps of expressing the protein or polypeptide in prokaryotic cells, harvesting the cells, directly solubilizing the cells in a buffer at pH of about ... | 08/12/2003 |
| 6599272 | Injection device and method for its operation Injector devices and methods for their operation for containers having an opening with or for an injection needle. The container is optionally of syringe type with a barrel of substantially constant axial cross-section. In one embodiment, the devices incl... | 07/29/2003 |
| 6566537 | Process and intermediates The invention relates to a process for the enantioselective preparation of tolterodine and analogues and salts thereof comprises the steps of: a) enantioselectively reducing the carbonyl function in a compound of formula (II): ##STR1## wherein R1 | 05/20/2003 |
| 6562006 | Injector device and method for its operation Injector device, and method for its operation, for containers of syringe type, comprising a barrel of axially roughly constant cross-section, a front opening and at least one movable wall inserted in the barrel for displacement of a container content, the... | 05/13/2003 |
| 6558395 | Intraocular lens implanter A device for deforming and ejecting a deformable intraocular lens for insertion into a small incision in an eye, the device comprising a) a housing, b) a lens transporting duct in a front part of the housing defining a duct axis, the duct having a front e... | 05/06/2003 |
| 6559120 | Recombinant allergen, fragments thereof, corresponding recombinant DNA molecules, vectors and hosts containing the DNA molecules, diagnostic and therapeutic uses of said allergens and fragments A recombinant DNA molecule comprising a nucleotide sequence (I) which codes for a polypeptide displaying the antigenicity of one, two or more of the Phi p I epitope clones (28, 34, 41, 42, 43, 45, 50, 52, 64, 80, 85, 86, 95, 97, 98, 103, 108, 109, 113, 11... | 05/06/2003 |
| 6547755 | Automated delivery device and method for its operation A delivery device including a) a housing, b) a container for a fluid arranged in the housing, the container having an opening, c) a delivery conduit connected in fluid communication with the opening, the conduit having a front end in flow respect distal f... | 04/15/2003 |
| 6537795 | Method and means for the production of hyaluronic acid A method for selecting streptococcus strains capable of producing hyaluronic acid with molecular weight exceeding six million includes the steps of cultivating strains of streptococci individually in culture medium which is free of metal ions which promot... | 03/25/2003 |
| 6528322 | Analytical method and apparatus The invention relates to a method for qualitative, semi-quantitative or quantitative determination of at least two analytes in an aqueous sample containing or suspected of containing the analytes, which method comprises the steps of: (i) providing a flow ... | 03/04/2003 |
| 6517864 | Transdermally administered tolterodine as anti-muscarinic agent for the treatment of overactive bladder Device for transdermal administration of tolterodine, optionally encompassing salts, prodrugs and metabolites thereof, optionally together with pharmaceutically acceptable carrier(s) to a human being or an animal in order to achieve an effect against over... | 02/11/2003 |
| 6423040 | Eye fluid applicator An eye fluid applicator. A hand grip part has a distal end and a proximal end. The distal end and the proximal end define an axis therebetween, a distal direction, and a proximal direction along the axis. A container includes a bottle part and a delivery ... | 07/23/2002 |
| 6399387 | Colored composition The present invention relates to new color compositions which are especially suitable to be used in oxygen indicators. The compositions comprise iron(II), an agent containing pyrogallol entities and an organic acid.... | 06/04/2002 |
| 6399734 | Photocurable siloxane polymers The present invention relates to photocurable siloxane polymers having functional acryl groups, useful in the preparation of intraocular lenses (IOLs). The polymers are siloxane copolymers, wherein the siloxane can be selected from the group consisting of... | 06/04/2002 |
| 6398771 | Containers for parenteral fluids A flexible transparent container for improved storage of oxygen sensitive parenterally administerable agents comprising an inner, primary container enclosed in a substantially oxygen impermeable outer envelope with an oxygen absorber, capable of consuming... | 06/04/2002 |
| 6392223 | Tilt sensing device and method for its operation A tilt sensing device and method for its operation, the device being of the type comprising (a) a housing, (b) a radiation transmitter and a radiation receiver arranged in or at the housing to form a beam path therebetween, (c) a radiation obstructing or ... | 05/21/2002 |