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| Number | Title | Issue Date |
| 7041450 | Method for diagnosing GH deficiency The present invention relates to a method and kit for diagnosing GH (growth hormone) deficiency, in particular isolated growth hormone deficiency II (IGHD II). The method comprises the steps of analysing the missense mutation G6191 to T in exon 4 of GH-1 ... | 05/09/2006 |
| 7033337 | Medical device The invention relates to an injector device for delivery of liquid from a high pressure source, and also to a method of performing such an injection. The device comprises a storage chamber 6, for the liquid or the liquid precursor components, comprising a sto... | 04/25/2006 |
| 6514498 | Modified/chimeric superantigens and their use A conjugate between a target-seeking moiety and a modified superantigen, characterized in that the superantigen is a wild-type superantigen (SA I) in which an amino acid residue in a superantigen region (region I) determining binding to TCR, referably TCR... | 02/04/2003 |
| 5807583 | Process for the preparation of sustained release pellets A process for the manufacture of sustained release pellets comprising pelletizing a mixture containing the drug in finely divided form and a binder. The characteristic feature is that: (a) said binder is in particle form consisting of one or more water-in... | 09/15/1998 |
| 5773472 | Method and means for prevention of cataract The present invention is related to the use of thiol-binding prostaglandins or prostaglandin-like substances containing alpha beta unsaturated ketone, esp. Prostaglandins of type A or J and derivatives or analogues thereof, for the preparation of ophthalm... | 06/30/1998 |
| 5556855 | N-heterocyclic substituted salicylic acids A compound of the formula Het--NR--SO2 --Ph2 --A--Ph1 (COOH)(OH) and tautomic form, salts, solvates, C1-6 alkyl esters and pharmaceutical compositions of the compound. Ph1 and Ph2 are benze... | 09/17/1996 |
| 5510382 | Method for composition for treatment of gastric and duodenal disorders The invention is related to the field of treating gastric and duodenal disorders and more specifically to the use of certain 13,14-dihydro-prostaglandin E derivatives, especially of PGE2, which are modified to contain a ring structure in the om... | 04/23/1996 |
| 5429838 | Method for the production of intraocular lenses In a method for producing intraocular lenses with improved optical properties, applying to the optical part of the lens a coating to protect the surface during one or more processing steps which are carried out under conditions so that the protective coat... | 07/04/1995 |
| 5403930 | Substituted salicylic acids A compound of the formula Het--NR--SO2 --Ph2 --A--Ph1 (COOH)(OH) and tautomic form, salts, solvates, C1-6 alkyl esters and pharmaceutical compositions of the compound. Ph1 and Ph2 are benze... | 04/04/1995 |
| 5375611 | Method for preventing secondary cataract Method for extracapsular cataract extraction with or without posterior chamber intraocular lens implantation comprising chemical modification of the posterior surface of the lens capsule, at least in the optical portion of said capsule, for preventing cel... | 12/27/1994 |
| 5376115 | Intraocular lens with vaulting haptic An intraocular lens that includes an optical lens body and haptics extending outwardly from the optical lens, said haptics extending at about a zero degree of angulation with respect to the lens body when not under compression and at least one haptic havi... | 12/27/1994 |
| 5252462 | Enzyme activity determinations method characterized by the using of substrates whose fluorescent properties differs those of the converted products The method for demonstrating the presence of an activity of an enzyme by (a) incubating said enzyme with a fluorogenic substrate A which is converted by the enzyme to a product B differing from A in respect to its fluorescent properties, A and/or B carrying a ... | 10/12/1993 |
| 5079253 | Composition for the topical treatment of glaucoma or ocular hypertension A method for the topical treatment of glaucoma or ocular hypertension which comprises contacting the surface of the eye with a composition consisting essentially of an effective intraocular pressure reducing amount of a mixture of (a) an adrenergic agonis... | 01/07/1992 |
| 5041133 | Intraocular implant An intraocular implant having an optic lens and haptic for fixation of said lens in the posterior or anterior chamber of the eye, said implant having thermal stability sufficient to render said implant autoclave sterilizable, said implant being chemically... | 08/20/1991 |
| 5036062 | Novel esters The present invention concerns novel compounds having the general formula ##STR1## wherein R1, R2 and R3 are selected form the group consisting of hydrogen or lower alkyl having 1-4 carbon atoms, wherein R2... | 07/30/1991 |
| 5034390 | Pyridyl-and pyrmidyl-piperazines useful for the treatment of mental disorders The present invention concerns novel compounds of the general formula; ##STR1## wherein R1 is halogen or hydrogen and R2 is halogen; X is either oxygen, sulfor or methylene R3 and R4 are the same or different an... | 07/23/1991 |
| 4997867 | Stable compositions A method of stabilizing an aqueous dispersion of water-absorbent particles and at least one matrix-forming hydrophilic thickening agent comprises the steps of evacuating gas from said dispersion and subjecting the latter to compression by means of a relat... | 03/05/1991 |
| 4973683 | Method of cross-linking a porous polysaccharide gel A porous polysaccharide gel is cross-linked in that (a) the gel is substituted with a monofunctional reagent having at least one functional group that can be activated, (b) the functional group of the reagent is activated, (c) the activated group is reacted, (d) th... | 11/27/1990 |
| 4963666 | Material of polysaccharides containing carboxyl groups, and a process for producing such polysaccharides Method of crosslinking carboxyl-containing polysaccharides in that the polysaccharide is at first activated with a bi- or polyfunctional reagent, and then after removal of any potential excess of activating reagent the crosslinking is performed during dry... | 10/16/1990 |
| 4948874 | Purified protein G from streptococcal bacteria A process is disclosed for recovering a cell wall protein, particularly a Fc-receptor, from streptococcal bacteria. In the process, streptococcal bacteria are treated with at least one proteolytic enzyme to solubilize the cell wall protein. A process is a... | 08/14/1990 |
| 4909992 | Device for handling porous matrixes and an analysis apparatus comprising the same A device for handling porous solid matrixes (16) in analytic determinations of the type comprising at least one reaction step, which is performed in the very matrixes by absorption of a liquid phase therein, comprises a holder (1) and at least one matrix ... | 03/20/1990 |
| 4904594 | Enzyme preparation capable of degrading glycosamino-glycan, and a method for producing said preparation Glycosaminoglycan-degrading enzyme preparation containing krill hyaluronidase, and a method of producing said preparation.... | 02/27/1990 |
| 4886787 | Method of preventing adhesion between body tissues, means for preventing such adhesion, and process for producing said means The invention is concerned with a method of preventing adhesions or accretions of body tissues inter se by means of employing a degradable gel of a crosslinked carboxyl-containing polysaccharide. The invention also covers a gel product to be used for this... | 12/12/1989 |
| 4877746 | Methods of carrying out assays for lipoproteins and apolipoproteins Method for carrying out immunochemical assays for lipoproteins and/or apolipoproteins, wherein prior to the reaction of the sample with the appropriate anti(apolipoprotein) or anti(lipoprotein) antibody the pH of the sample is maintained at a non-denaturi... | 10/31/1989 |
| 4874491 | Method of supplying buffer solutions to electrophoretic separation procedures The process is one concerned with the field of electrophoresis and relates more particularly to a method of supplying the electrode buffer solutions by means of using buffer-containing gels as buffer reservoirs, thus making it unnecessary for the electrop... | 10/17/1989 |
| 4865728 | Adaptor for allowing different gel bed heights in a chromatographic separation column To allow different gel bed heights in a chromatographic separation column (1), a plunger (6) is displaceable within the column (1) into contact with the gel bed (5) by means of a shaft (7) extending through an end piece (3) at the end of the column (1), s... | 09/12/1989 |
| 4844782 | Method in staining and destaining of electrophoretic gels Method in the after-treatment of electrophoretic gels containing separated components, in that the gel is caused to rotate in a selected fixation, staining or destaining solution during at least a part of the total processing time which is calculated from... | 07/04/1989 |
| 4826771 | Procedure to be performed in conjunction with protein blotting or nucleic acid blotting Procedure to be performed in conjunction with protein blotting or nucleic acid blotting wherein the matrix to which said components have been transferred is contacted with reagent and wash solutions in a rotary drum.... | 05/02/1989 |
| 4826776 | Method for determining hyaluronic acid, and a reagent kit for said method Method in determining hyaluronic acid by means of inhibition technique where in addition to the hyaluronic acid of the sample (analyte) a first reactant possessing hyaluronic acid structure (reactant (1), derivatized hyaluronic acid) and a second reactant... | 05/02/1989 |
| 4814437 | Method for preparation of sulfated polysaccharides by treating the polysaccharide with a reducing agent before sulfation A new method for preparation of sulfated polysaccharides by means of pyridine-chlorosulfonic acid reagents. The polysaccharide is before sulfation treated with a reducing agent, e.g. sodium borohydride.... | 03/21/1989 |
| 4804537 | Sperm selection process using a salt of hyaluronic acid The present invention relates to a process and means for separating motile sperm cells in vitro from an aqueous sperm-containing sample by means of contacting said sample with a layer of an aqueous artificial penetration medium for sperm cells, said mediu... | 02/14/1989 |
| 4801619 | Hyaluronic acid preparation to be used for treating inflammations of skeletal joints Hyaluronic acid preparation containing an effective amount of hyaluronic acid of a molecular weight exceeding 3×106 dalton, for intra-articular administration in the treatment of steroid arthropathy and progressive cartilage degeneration cause... | 01/31/1989 |
| 4797277 | Method for reperfusion therapy Method for reperfusion therapy of a mammalian organ comprising the step of administering systemically to said organ a therapeutically active amount of an antibody preparation having specificity for a LAC-epitope that is responsible for leukocyte-endotheli... | 01/10/1989 |
| 4797370 | Antibody preparation with specificity for 4-(2-Aminoethyl) Imidazoyl group manufacture and use of the antibody preparation Antibody preparation containing antibodies or fragments or derivatives thereof which possess biospecific immunotype affinity to a 4-(2-aminoethyl)imidazolyl group bound to an aliphatic carbon atom; process for manufacturing said preparation; and process f... | 01/10/1989 |
| 4795461 | UV absorbing lens material The invention is concerned with a UV absorbing plastics material to be used in intraocular lenses, said material having been produced by means of incorporating in the plastics monomer mixture, prior to the polymerization thereof, a combination of chromoph... | 01/03/1989 |
| 4778768 | Method of monitoring the progressive destruction of articular cartilage in a joint Method of determining changes occurring in articular cartilage. The method involves (a) quantifying proteoglycan monomer and/or antigenic fragments thereof in a synovial fluid sample and (b) correlating the values thus obtained with progressive destructio... | 10/18/1988 |
| 4772419 | Shaped article and processes for its preparation A shaped article based upon cross-linked, possibly derivatized hyaluronic acid or a salt thereof is characterized in that it has a dry matter content of at least 65 percent by weight and a tensile strength of at least 2 N/cm2. The shaped articl... | 09/20/1988 |
| 4764360 | Composition for ophthalmological use A composition to be used in ophthalmology and containing an aqueous solution of a high molecular polymer to which has been added a polymeric dye having a molecular weight higher than 10,000.... | 08/16/1988 |
| 4752571 | Method for determining certain bacterial polypeptides and antibodies directed against them Method and means in/for the immunoassay determination of (I) a bacterial polypeptide capable of binding to the Fc protion of an immunoglobulin and/or (II) the high affinity antibody to said polypeptide. The characteristic feature of the method resides in ... | 06/21/1988 |
| 4725585 | Method of enhancing the host defense The invention relates to a method of enhancing or regulating the host defense of a mammal, said method comprising administering to a mammal a therapeutically effective amount of hyaluronic acid.... | 02/16/1988 |
