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A method of swing on a swing is disclosed, in which a user positioned on a standard swing suspended by two chains from a substantially horizontal tree branch induces side to side motion by pulling alternately on one chain and then the other.
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| Number | Title | Issue Date |
| RE39149 | Method of administering azithromycin An oral dosage form of azithromycin which does not exhibit an adverse food effect; Specific azithromycin oral dosage forms including tablets, powders for oral suspensions and unit dose packets; Methods of treating microbial infections with the dosage forms; And ther... | 06/27/2006 |
| 7063971 | Phosphodiesterase enzymes Amino acid sequences and nucleotide sequences relating to PDEXV are described. In a preferred aspect, the amino acid sequence comprises the sequence presented as SEQ ID NO:1. ... | 06/20/2006 |
| 7060836 | Lactams as tachykinin antagonists Compounds of the formula (I): or a pharmaceutically acceptable salt, prodrug, solvate or polymorph thereof, wherein R, R1, and Z are as defined herein, are useful in treating or preventing a condition ... | 06/13/2006 |
| 7060805 | Methods for isolating tissue factor inhibitor A cDNA clone having a base sequence for human tissue factor inhibitor (TFI) has been developed and characterized and the amino acid sequence of the TFI has been determined. ... | 06/13/2006 |
| 7056918 | Benzimidazole anti-inflammatory compounds The present invention relates to novel triazolo-pyridines of the formula I wherein Het is an optionally substituted 5-membered heterocycle containing one to two heteroatoms selected from nitrogen, sulfur and oxyg... | 06/06/2006 |
| 7056933 | Heterocyclo-alkylsulfonyl pyrazoles The present invention relates to heterocyclo alkylsulfonyl pyrazoles of the formula I: wherein the ring of the formula (R5)—A—(SOmR4), m, X, R1 through R5 | 06/06/2006 |
| 7056492 | Mycoplasma hyopneumoniae vaccine and methods for reducing Mycoplasma bovis pneumonia in cattle The present invention relates to methods for treating or preventing a disease or disorder in an animal caused by infection by Mycoplasma bovis (M. bovis) by administering to the animal an effective amount of a Mycoplasma hyopneumoniae (M. hyo... | 06/06/2006 |
| 7056930 | 2-Azabicyclo[3.3.1]nonane derivatives The subject invention relates to 2-azabicyclo[3.3.1]nonane derivatives, pharmaceutical compositions comprising such derivatives and methods of using such derivatives to treat disease states, disorders and conditions mediated by opioid receptors. The subject inventio... | 06/06/2006 |
| 7053212 | Acyclic amide and sulfonamide ligands for the estrogen receptor The present invention provides estrogen receptor (ER) ligands of structural formula (I) the pharmaceutically acceptable salts, stereoisomers, and prodrugs thereof, and the pharmaceutically acceptable salts of the... | 05/30/2006 |
| 7053192 | Crystal forms of azithromycin The invention relates to novel crystal forms of azithromycin, an antibiotic useful in the treatment of infections. ... | 05/30/2006 |
| 7052895 | Phosphodiesterase enzymes Amino acid sequences and nucleotide sequences relating to PDE1B2 are described. In a preferred aspect, the amino acid sequence comprises the sequence presented as SEQ ID No. 1. ... | 05/30/2006 |
| 7053095 | Triazole compounds as transforming growth factor (TGF) inhibitors Novel triazole compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of transforming gro... | 05/30/2006 |
| 7049335 | 3-azabicyclo[3.1.0]hexane derivatives The subject invention provides a compound of the formula I, wherein X, Q, n, R1, R2, R3, R4, R5, R6, R7, R8, R9, ... | 05/23/2006 |
| 7049444 | 3-azabicyclo[3.1.0]hexane derivatives useful in therapy Compounds of formula (I), their salts and prodrugs thereof, where the substituents are as defined herein are disclosed as opiate binding agents useful in the treatment of opiate-mediated conditions. Also described are processes for making such substances. | 05/23/2006 |
| 7045653 | Pharmaceuticals The invention relates to NEP inhibitors for treating cardiovascular disorders. Preferred NEP inhibitors are compounds of formula (I) wherein R1 is C1–C6alkyl, C1–C6alkoxyC1–C3alkyl or... | 05/16/2006 |
| 7041667 | CCR5 modulators Compounds of Formula 1 [Region α]—[Region β]—[Region γ]—[Region δ] (1) which are useful as modulators of chemokine activity. The invention also provides pharmaceutical formulations and m... | 05/09/2006 |
| 7041672 | Substituted aryl 1, 4-pyrazine derivatives Substituted aryl pyrazine derivatives of the formula I as defined herein, and their use in treating anxiety disorders, depression and stress related disorders are disclosed. ... | 05/09/2006 |
| 7037923 | Alkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines The present invention relates to novel alkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines, to intermediates and methods for their preparation, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the present invention a... | 05/02/2006 |
| 7030157 | Pharmaceutical compositions, kits and methods comprising combinations of estrogen agonists/antagonists, estrogens and progestins The present invention relates to pharmaceutical compositions, kits and methods comprising combinations of (−)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalene-2-ol or nontoxic pharmacologically acceptable acid addition salts ther... | 04/18/2006 |
| 7029887 | Methods related to gene directing the ratio of B2:B1 avermectins The present invention relates to polynucleotide molecules comprising sequences encoding avec gene products, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures of Streptomyces avermiti... | 04/18/2006 |
| 7030125 | Isothiazole and isoxazole compounds as transforming growth factor (TGF) inhibitors Novel isothiazole and isoxazole compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of... | 04/18/2006 |
| 7026345 | Resolution of 3-amino alkylnitriles The present invention relates to chiral N-acetyl-alpha-amino acid salts of optically active β-amino alkylnitriles, and also to a process for preparing optically active β-amino alkylnitriles by resolving racemic β-amino alkylnitriles using chiral N-acetyl-alpha-am... | 04/11/2006 |
| 7022684 | Treatment of rumen acidosis with α-amylase inhibitors The invention described herein relates to: the use of an effective inhibitor of a bacterial α-amylase and/or α-glucosidase in the manufacture of a composition for the treatment of rumen acidosis; a method of treatment of rumen acidosis which comprises administrati... | 04/04/2006 |
| 7018818 | Intermediates in the preparation of therapeutic fused bicyclic amino acids The invention presents compounds of formula (I), where R represents H or a suitable carboxylic acid protecting group, which are intermediates in the preparation of therapeutic fused bicyclic amino acids. ... | 03/28/2006 |
| 7019009 | Acyl derivatives of 5-(2-(4-(1,2 benzisothiazole-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one having neuroleptic activity A process for preparing acyl derivatives as prodrugs of 5-(2-(4-(1,2 benzisothiazole-3-yl)-1-piperazinyl)ethyl-6-chloro-1,3-dihydro-2H-indol-2-one and pharmaceutically acceptable acid addition salts and methods of use as an antipsychotic. ... | 03/28/2006 |
| 7019147 | Benzimidazole derivatives useful as antiproliferative agents The invention relates to compounds of formula (1) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R7, R8, R9, R10, and R11 are as defined herein. The invention als... | 03/28/2006 |
| 7019142 | Process for preparing naphthyridones and intermediates A process for preparing a naphthyridone carboxylic acid and its derivatives makes use of side chain intermediates of formulae I and IV herein. ... | 03/28/2006 |
| 7015203 | Macrolides The invention relates to novel erythromycin analogs and azalides, particularly ones with novel C-13 substituents, and to pharmaceutically acceptable salts thereof. The compounds of this invention are antibacterial agents that may be used to treat various bacterial a... | 03/21/2006 |
| 7012078 | 2-aminopyridines containing fused ring substituents The present invention relates to 2-aminopyridine derivatives of the formula wherein G, R1 and R2 are defined as in the specification, that exhibit activity as nitric oxide synthase (NOS) inhibitor... | 03/14/2006 |
| 7012080 | Imidazopyridine compounds as 5-HT receptor agonists This invention provides a compound of the formula (I): or a pharmaceutically acceptable salt thereof, wherein R1 represents a hydrogen atom or a halogen atom; R2 represent... | 03/14/2006 |
| 7012083 | Compounds useful in therapy There is provided a compound of formula I, wherein R1, R2, R3 and Y have meanings given in the description, which are useful in the prophylaxis and in the treatment of pruritus. ... | 03/14/2006 |
| 7005523 | Cycloalkyl-[4-(trifluorophenyl)-oxazol-5yl]-triazolo-pyridines The present invention relates to novel cycloalkyl-[4-(trifluorophenyl)-oxazol-5-yl]-triazolo-pyridines, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the present invention are pote... | 02/28/2006 |
| 7005520 | Process for the preparation of pyrazolopyrimidinones There is provided a process for the production a compound of general formula I: wherein A, R1, R2, R3 and R4 have meanings given in the description, which process comprises th... | 02/28/2006 |
| 7001747 | Nucleic acid molecules encoding modified polyketide synthases containing polylinkers and uses thereof Nucleic acid molecules encoding at least part of a Type I polyketide synthase, and having a polylinker with multiple restriction enzyme sites in place of one or more PKS genes encoding enzymes associated with reduction, optionally further including nucleic acid inco... | 02/21/2006 |
| 7001900 | Azabicyclic compounds for the treatment of disease The invention provides compounds of Formula I: wherein Azabicyclo is W is a six-membered heterocyclic ring system having 1–2 nitrogen atoms or a 10-membered bicyclic-six-... | 02/21/2006 |
| 6998423 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders includ... | 02/14/2006 |
| 6995159 | 5-HT receptor ligands and uses thereof Compounds of Formula (IC) that act as 5-HT receptor ligands and their uses in the treatment of diseases linked to the activation of 5-HT2 receptors in animals are described herein . ... | 02/07/2006 |
| 6992101 | N-(indole-2-carbonyl) and H-thieno[2,3-b]pyrrole-5-carboxamide anti-diabetic agents The present invention provides compounds of formula (I) the prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein R′, R″, R′″, and Z are as defined herein; pharmaceut... | 01/31/2006 |
| 6992188 | Substituted heterocyclic derivatives Corticotropin-releasing factor (CRF) antagonists having the formula wherein the dashed lines, A, B, D E, F, Z, G, R3, and R5 having the definitions set forth in the specification pharmaceutical com... | 01/31/2006 |
| 6991916 | Compounds for the treatment of sexual dysfunction Polynucleotide and polypeptide sequences are described. The polypeptide sequences comprise one or more of: (a) a polypeptide having the deduced amino acid sequence translated from the polynucleotide sequence in SEQ ID NO: 1 or SEQ ID NO: 5 and variants, fragments, h... | 01/31/2006 |
