In 1608, Dutch eyeglass maker Hans Lipperhey filed the first patent for a working telescope. The patent was denied.
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| Number | Title | Issue Date |
| 8182768 | Interface assembly for pre-concentrating analytes in chromatography A system for interfacing a sampling device and a chromatograph and for pre-concentrating analytes in a sample prior to introducing the sample into the chromatographic column is generally disclosed comprising an interface housing with a first channel and an adsorbent... | 05/22/2012 |
| 8167987 | Methods and systems for cooling a chromatographic column Systems and methods for cooling a chromatographic column is disclosed generally, comprising heating a chromatographic column, supplying fluid into the column via the inlet end of the column at an inlet pressure, decreasing the temperature of the column, thereby caus... | 05/01/2012 |
| 8017734 | Kit for diagnosis of pre-eclampsia The present invention relates to a method of predicting pre-eclampsia (PE). The present invention also relates to a diagnostic kit for performing a method of predicting PE. In particular, the method determining the level of two or more markers selected from placenta... | 09/13/2011 |
| 7736908 | Method and apparatus for improved gas detection The invention relates to a method and apparatus for providing a reactor having a heater, a passage for transporting a reactant, and a chamber containing a gas sample and being coupled to the passage for receiving the reactant and mixing the reactant with the gas sam... | 06/15/2010 |
| 7736479 | Electrochemical sensor having nonporous working electrode The invention relates to an electrochemical gas sensor having a substrate, substrate surface for depositing electrodes thereon, counter and sensing electrodes for measuring current flow, an electrolyte for providing an electrical connection between the electrodes, a... | 06/15/2010 |
| 7711523 | System for remote monitoring and control of an instrument The invention relates to a web-based instrument and data management system and method including software executing on an instrument controller computer system that receives a web file from a web browsing software executing on a remote computer. The web-based interfa... | 05/04/2010 |
| 7709267 | System and method for extracting headspace vapor A system and method for extracting headspace vapor is generally disclosed comprising pressurizing a vessel containing headspace vapor with a carrier gas and subsequently venting the sample mixture through an adsorbent trap and out a vent. A flow controller is employ... | 05/04/2010 |
| 7691181 | System for controlling flow into chromatographic column using transfer line impedance A system for controlling the flow rate into a chromatographic column is disclosed generally comprising communicating a fluid to the column through a transfer line, measuring the inlet pressure, determining the outlet pressure, and adjusting the applied pressure unti... | 04/06/2010 |
| 7677795 | Differential scanning calorimeter (DSC) with temperature controlled furnace A differential scanning calorimeter apparatus includes reference and sample cells and controlled temperature shields. The temperature of the shields is controlled such that baseline curvature is reduced by eliminating heat flow from the furnaces to their surrounding... | 03/16/2010 |
| 7662630 | Method for verifying the integrity of thermal desorption sampling tubes An analyte of a sample is transferred to an analytical instrument by introducing a quantity of a compound of a standard material into a vessel containing an adsorbent material; introducing a quantity of the analyte of the sample into the vessel; and transferring the... | 02/16/2010 |
| 7658823 | Interdigitated electrochemical gas generator The invention relates to an electrochemical gas generator including a substrate for providing a surface for electrode deposition, a first electrode deposited on the surface for providing an electrical connection with a conducting medium, a second electrode deposited... | 02/09/2010 |
| 7656521 | Method of instrument standardization for a spectroscopic device In a spectroscopic process a sample for producing a test spectral line or spectrum of at least one component contained in the sample is stimulated and the transmitted and/or emitted electromagnetic rays are used to create the test spectral line or spectrum. In order... | 02/02/2010 |
| 7652129 | Parallel process for protein or virus separation from a sample A sample is divided into a series of aliquots with the aliquots being subjected to at least two successive parallel separation steps in order to resolve protein or viral components thereof. The separation steps are performed not only on a sample but subsamples each ... | 01/26/2010 |
| 7638287 | Detecting and predicting pre-eclampsia The technology described herein relates to methods of detecting or predicting pre-eclampsia (PE). The technology described herein also relates to commercial packages, such as diagnostic kits, for performing a method of detecting or predicting PE. In particular, the ... | 12/29/2009 |
| 7601250 | Hybrid film type sensor A miniaturized gas sensor comprised of thick- or thin-film type electrodes, on a non-conductive supportive substrate, and in contact with a solid ionomer electrolyte, for the detection of toxic gases, i.e., carbon monoxide, and other oxidizable or reducible gases an... | 10/13/2009 |
| 7601233 | Electrochemical gas sensor with passage for receiving gas The invention relates to an electrochemical gas sensor having improved response time and sensitivity. The electrochemical gas sensor includes a substrate for providing a surface upon which a film of conductive material may be deposited, a pair of electrodes deposite... | 10/13/2009 |
| 7595884 | Measurement of sample reflectance An accessory for a spectrometer for carrying out measurements of specular reflectance of a sample. The accessory is designed so that all components can be located in a housing and the sample can be located horizontally on a top-plate of the housing with the componen... | 09/29/2009 |
| 7572319 | Analyte pre-concentrator for gas chromatography An analyte pre-concentrator for gas chromatography is disclosed generally comprising a tube packed with an adsorbent, wherein the tube may serve as the liner of a chromatographic injector, as an adsorbent trap coupled to a chromatographic column, and/or as an adsorb... | 08/11/2009 |
| 7552618 | Chromatographic interface for thermal desorption systems Disclosed are systems and methods that include a thermal desorption unit, a chromatographic column, and an interface device between the unit and the column. The interface device controls the fluid flowing into the column, such as by providing additional carrier gas ... | 06/30/2009 |
| 7536926 | Dispensing apparatus having means for loading pipette tips in a dispense head A self contained dispensing head apparatus wherein a modified pipette tip box tray carrier is utilized to furnish pipette tips, carried in a standard pipette tip box, by a pipette tip box tray carrier to the head apparatus and wherein means are provided to engage th... | 05/26/2009 |
| 7534286 | Methods and systems for cooling a chromatographic column Systems and methods for cooling a chromatographic column is disclosed generally, comprising heating a chromatographic column, supplying fluid into the column via the inlet end of the column at an inlet pressure, decreasing the temperature of the column, thereby caus... | 05/19/2009 |
| 7521245 | Method for washing and drying pins in microarray spotting instruments A method and apparatus are provided for washing and drying pins in a microarray spotting instrument. The apparatus includes an array of chambers, each for receiving one of the pins of the spotting instrument. To wash the pins, streams of wash fluid are directed at t... | 04/21/2009 |
| 7468095 | System for controlling flow into chromatographic column using transfer line impedance A system for controlling the flow rate into a chromatographic column is disclosed generally comprising communicating a fluid to the column through a transfer line, measuring the transfer line inlet pressure, determining the transfer line outlet pressure, and adjusti... | 12/23/2008 |
| 7459313 | Method for measuring effective temperature inside a sealed container A method of measuring the effective temperature inside a sealed container having a headspace is provided. A liquid solvent is added to the container, and a solid compound is added to the liquid solvent to create a saturated solution. Vapor of the saturated solution ... | 12/02/2008 |
| 7448796 | Differential scanning calorimeter (DSC) with temperature controlled furnace A differential scanning calorimeter apparatus includes reference and sample cells and controlled temperature shields. The temperature of the shields is controlled such that baseline curvature is reduced by eliminating heat flow from the furnaces to their surrounding... | 11/11/2008 |
| 7431884 | Chemical assays An assay device in which to carry out a fluid-phase chemical assay, comprising means for supporting a test substrate, a sample chamber for receiving a fluid sample and at least one fluid control device for controlling the movement of fluid into and/or out of the sam... | 10/07/2008 |
| 7429362 | Method and apparatus for improved gas detection The invention relates to a method and apparatus for providing a reactor having a heater, a passage for transporting a reactant, and a chamber containing a gas sample and being coupled to the passage for receiving the reactant and mixing the reactant with the gas sam... | 09/30/2008 |
| 7422855 | Multiplexing assays for analyte detection High density multiplexing assays for proteins, nucleic acids, and other molecules are described based upon using mass spectrometry detection. A solid-state support assay format is utilized, whereby, the bead carries both a coding molecule to track the sample or anal... | 09/09/2008 |
| 7422646 | Electrochemical sensor with dry ionomer membrane and methodfor making the same A miniaturized gas sensor comprised of film type electrodes, on a non-conductive supportive substrate, and in contact with a dry ionomer electrolyte, for detection of toxic gases, i.e., carbon monoxide, and other oxidizable or reducible gases and vapors and method o... | 09/09/2008 |
| 7422625 | Methods and systems for characterizing a sorbent tube Disclosed are systems and methods that include providing a vessel having an inlet and an outlet for communicating a carrier gas through the vessel; determining a differential pressure between the inlet and the outlet for a known flow rate at the outlet; and, determi... | 09/09/2008 |
| 7405821 | Method of instrument standardization for a spectroscopic device In a spectroscopic process a sample for producing a test spectral line or spectrum of at least one component contained in the sample is stimulated and the transmitted and/or emitted electromagnetic rays are used to create the test spectral line or spectrum. In order... | 07/29/2008 |
| 7404882 | Film-type solid polymer ionomer sensor and sensor cell A miniaturized gas sensor including film type electrodes, and a solid ionomer electrolyte, for the detection of toxic gases, i.e., carbon monoxide, and other oxidizable or reducible gases and vapors is described. The all-solid planar sensor cell has two or more film... | 07/29/2008 |
| 7387037 | Dispensing apparatus A pin support assembly includes a pin support frame having a plurality of apertures for supporting an array of pins for dispensing fluids. The pins are supported for longitudinal or “floating” movement to prevent damage to the pins. An actuation assembly engages... | 06/17/2008 |
| 7371006 | Differential scanning calorimeter (DSC) with temperature controlled furnace A differential scanning calorimeter apparatus includes reference and sample cells and controlled temperature shields. The temperature of the shields is controlled such that baseline curvature is reduced by eliminating heat flow from the furnaces to their surrounding... | 05/13/2008 |
| 7361208 | Chromatography oven with heat exchange and method of use Methods and systems for cooling gas chromatography ovens that comprise a housing having a fluid entry and a sleeve positioned within the housing to provide a fluid gap between the inner surface of the housing and the outer surface of the sleeve, where the sleeve is ... | 04/22/2008 |
| 7358485 | Zirconia toughened alumina composition and use in ion and electron optical systems An ion optical system including an ionizer for ionizing one or more compounds, the ionizer including a plurality of components, a mass separator for separating ions of the one or more compounds, the mass separator including a plurality of components, and a detector ... | 04/15/2008 |
| 7328135 | System for remote monitoring and control of an instrument The invention relates to a web-based instrument interface including software executing on an instrument controller computer system that receives a web file from a web browsing software executing on a remote computer. The web-based interface also extracts a command o... | 02/05/2008 |
| 7311757 | Analyte pre-concentrator for gas chromatography An analyte pre-concentrator for gas chromatography is disclosed generally comprising a tube having a restricted outlet and packed with an adsorbent, wherein the tube serves as the liner of a chromatographic injector, as an adsorbent trap coupled to a chromatographic... | 12/25/2007 |
| 7300564 | Interdigitated electrochemical gas generator The invention relates to an electrochemical gas generator including a substrate for providing a surface for electrode deposition, a first electrode deposited on the surface for providing an electrical connection with a conducting medium, a second electrode deposited... | 11/27/2007 |
| 7291474 | Hydrolytic substrates for an analyte-dependent enzyme activation system Disclosed are compounds of the general formulas: wherein Y is a moiety capable of being cleaved by a hydrolytic enzyme; L is a detectable label; X is a linking group; Z is a halogen; and R is hydrogen, an alkyl, ... | 11/06/2007 |