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Assignee: Otsuka Pharmaceutical Company Limited


Location: Tokyo, JP
No. of patents: 14

NumberTitleIssue Date
7138143Coated preparation soluble in the lower digestive tract
A coating dispersion soluble in the lower digestive tract which is prepared by blending a hydroxypropyl methylcellulose acetate succinate (HPMCAS) soluble at around pH 7 with a conventional plasticizer and an anion surfactant and further adding an acid, wherein the ...
11/21/2006
6743806Active oxygen scavenger
A new active oxygen scavenger which comprises as an active ingredient a tetrazolylalkoxy-dihydrocarbostyril compound of the formula (I): wherein R is cycloalkyl group, A is lower alkylene group, and the bond between 3- a...
06/01/2004
5723648Intermediates for anti-microbial benzoheterocyclic compounds
Novel 4-oxoquinoline-3-carboxylic acid compounds of the formula: ##STR1## wherein R1 is cyclopropyl which may have 1 to 3 substituents of alkyl and halogen; phenyl which may be substituted by 1 to 3 substituents of alkoxy, halogen and OH; ...
03/03/1998
5591744Benzoheterocyclic compounds
Novel 4-oxoquinoline-3-carboxylic acid compounds of the formula: ##STR1## wherein R1 is cyclopropyl which may have 1 to 3 substituents of alkyl and halogen; phenyl which may be substituted by 1 to 3 substituents of alkoxy, halogen and OH; ...
01/07/1997
5266577Method of treating congestive heart failure using carbostyril derivatives
Method for the treatment of congestive heart failure or paroxymal frequent heart pulse using a carbostyril derivative of formula: ##STR1## wherein R1 is H or CN, and R2 and R3 are each H, alkyl optionally substituted ...
11/30/1993
4786649Antimicrobial 1-thienyl-4-oxoquinoline-3-carboxylic acids
Novel 1-thienyl-4-oxoquinoline-3-carboxylic acid compounds of the formula ##STR1## wherein R1 is an amino (lower) alkyl, R2 is thienyl, and X is a halogen atom, and a pharmaceutically acceptable salt thereof, said compounds havi...
11/22/1988
4684648Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds and compositions thereof
Novel 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds of the formula: ##STR1## wherein R is hydrogen atom or fluorine atom, R° is hydroxy, fluorine atom or an alkanoyloxy having 1 to 6 carbon atoms, and X1 is hydrogen...
08/04/1987
4593035Carbostyril derivatives
Novel carbostyril derivatives of the formula: ##STR1## wherein R1 is hydrogen atom or a lower alkyl group, R2 is a lower alkyl group or a group of the formula: ##STR2## R3 is a lower alkylthio group, a lower alky...
06/03/1986
40268975-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxycarbostyril derivatives
5-[1-Hydroxy-2-(substituted-amino)]alkyl -8-hydroxy-carbostyril derivatives represented by the formula (I) ##STR1## wherein R1 represents an alkyl group having 1 to 4 carbon atoms and R2 and R3, which may be the same ...
05/31/1977
40227765-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives
5-[Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-carbostyril derivatives represented by the formula (I) ##STR1## wherein R1 and R2, which may be the same or different, each represents a hydrogen atom, an alkyl group having 1 to ...
05/10/1977
40227845-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives
5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril derivatives and 5-[1-hydroxy-2-(substituted-amino)]-alkyl-8-substituted-3,4-dihydrocarbost yril derivatives represented by the formulas (Ia) and (Ib) ##STR1## WHEREIN R1
05/10/1977
39949015-[1-Hydroxy-2-(s ubstituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives
5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxy-3,4-dihydrocarbostyril derivatives having the formula (I) ##SPC1## wherein R1 represents an alkyl group having 1 to 4 carbon atoms, and R2 and R3, which may be the same or...
11/30/1976
39753915-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dih ydrocarbostyril derivatives
5-[1-HYDROXY-2-SUBSTITUTED-AMINO)]ETHYL-8-HYDROXY-3,4-DIHYDROCARBOSTYRIL DERIVATIVES REPRESENTED BY THE FORMULA (I) ##SPC1## wherein R1 and R2, which may be the same or different, each represents a hydrogen atom, an alkyl group havin...
08/17/1976
3969507Method of preventing and treating thrombosis
A method of preventing and treating thrombosis comprising administering a therapeutically effective amount of 5-(hydroxy-3-t-butylamino)propoxy-3,4-dihydrocarbostyril having the formula ##EQU1##...
07/13/1976
 
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