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| Number | Title | Issue Date |
| 8124734 | Human genes relating to respiratory diseases and obesity This invention relates to isolated nucleic acids comprising genes of human chromosome 12q23-qter and the proteins encoded by these genes. Expression vectors and host cells containing such genes or fragments thereof, as well as antibodies to the proteins encoded by t... | 02/28/2012 |
| 8105826 | Nucleotide and amino acid sequences relating to respiratory diseases and obesity This invention relates to genes identified from human chromosome 12q23-qter, which are associated with various diseases, including asthma. The invention also relates to the nucleotide sequences of these genes, isolated nucleic acids comprising these nucleotide seque... | 01/31/2012 |
| 7928200 | Human genes relating to respiratory diseases and obesity This invention relates to isolated nucleic acids comprising genes of human chromosome 12q23-qter and the proteins encoded by these genes. Expression vectors and host cells containing such genes or fragments thereof, as well as antibodies to the proteins encoded by t... | 04/19/2011 |
| 7867699 | Method of synthesizing and purifying Dkk proteins and Dkk proteins obtained thereby The invention relates to a novel method of inexpensively synthesizing large quantities of an essentially pure, biologically active, glycosylated Dkk protein, including mammalian and human Dkk proteins (e.g., human Dkk1). The invention further relates to the syntheti... | 01/11/2011 |
| 7700101 | Reagents and method for modulating Dkk-mediated interactions The present invention provides reagents, compounds, compositions, and methods relating to novel interactions of the extracellular domain of LRP5, HBM (a variant of LRP5), and/or LRP6 with Dkk, including Dkk-1. The various nucleic acids, polypeptides, antibodies, ass... | 04/20/2010 |
| 7642245 | Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif Compounds of the formula (I) where Ar and R are as defined herein, possess antibacterial properties. ... | 01/05/2010 |
| 7517684 | Nucleic acid and amino acid sequences relating to for diagnostics and therapeutics The invention provides isolated polypeptide and nucleic acid sequences derived from Pseudomonas aeruginosa that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypept... | 04/14/2009 |
| 7504490 | Nucleic acid and amino acid sequences relating to for diagnostics and therapeutics The invention provides isolated polypeptide and nucleic acid sequences derived from Aspergillus fumigatus that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypepti... | 03/17/2009 |
| 7501118 | Human gene relating to respiratory diseases and obesity This invention relates to isolated nucleic acids comprising genes of human chromosome 20p13-p12 and the proteins encoded by these genes. Expression vectors and host cells containing such genes or fragments thereof, as well as antibodies to the proteins encoded by th... | 03/10/2009 |
| 7416849 | HBM variants that modulate bone mass and lipid levels The present invention relates to methods and materials used to express an HBM-like polypeptide derived from HBM, LRP5 or LRP6 in animal cells and transgenic animals. The present invention also relates to transgenic animals expressing the HBM-like polypeptides. The i... | 08/26/2008 |
| 7407804 | Human genes relating to respiratory diseases and obesity This invention relates to isolated nucleic acids comprising genes of human chromosome 12q23-qter and the proteins encoded by these genes. Expression vectors and host cells containing such genes or fragments thereof, as well as antibodies to the proteins encoded by t... | 08/05/2008 |
| 7317001 | Use of ramoplanin to treat diseases associated with the use of antibiotics The invention features a method of treating or preventing a disease associated with the use of antibiotics in a patient in need thereof by administering to the patient ramoplanin in an amount and for a duration effective to treat said disease. The disease may be cau... | 01/08/2008 |
| 7241613 | Identification of cell surface proteins and their uses The invention provides for novel polypeptides of Candida species found on the cell wall of the Candida organism. The invention further provides for methods of using these polypeptides, the genes encoding the polypeptides and fragments thereof for prepa... | 07/10/2007 |
| 7205146 | Nucleotide and amino acid sequences relating to respiratory diseases and obesity This invention relates to genes identified from human chromosome 12q23-qter, which are associated with various diseases, including asthma. The invention also relates to the nucleotide sequences of these genes, isolated nucleic acids comprising these nucleotide seque... | 04/17/2007 |
| 7151161 | Human genes of chromosome 11q13.3 This invention relates to isolated nucleic acids comprising novel genes of a 20 cM region of human chromosome 11q13.3 and the proteins encoded by these genes. Expression vectors and host cells containing these genes or fragments thereof, as well as antibodies to the... | 12/19/2006 |
| 7129214 | Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif Compounds of the formula (I) where Ar and R are as defined herein, possess antibacterial properties. ... | 10/31/2006 |
| 7090973 | Nucleic acid sequences relating to for diagnostics and therapeutics The invention provides isolated polypeptide and nucleic acid sequences derived from Bacteroides fragilis that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptid... | 08/15/2006 |
