Bizarre Patents
Mouse device with a built-in printer
A mouse device for use as an input device of a computer is provided that includes a housing in which recording paper is loadable, and a printer unit provided within the housing for printing on the recording paper print information received from the computer.
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| Number | Title | Issue Date |
| 8180134 | In vivo structural and flow imaging Embodiments of the present invention include but are not limited to methods and systems for optical coherence imaging. A method for optical coherence imaging may comprise scanning a sample with an incident beam from a light source; detecting one or more spectral int... | 05/15/2012 |
| 8171562 | System and methods for protecting against denial of service attacks A system and methods utilizing the network layer to provide security in distributed computing systems in order to thwart denial of service attacks. The system and methods of the present invention utilize puzzles placed at the network layer level to protect against d... | 05/01/2012 |
| 8158435 | Tandem mass spectrometry for detecting and/or screening for conditions associated with altered sterols Embodiments of the present invention provide for detecting and/or screening for conditions associated with altered sterols by derivatization of sterols to provide suitable sensitivity and selectivity of detection using tandem mass spectrometry with electrospray ioni... | 04/17/2012 |
| 8124397 | Inactivating pathogens with oxidizing agents for vaccine production The present disclosure provides methods for producing a vaccine composition containing a pathogen that is rendered noninfectious by exposure to hydrogen peroxide. The methods disclosed herein are suitable for the preparation of vaccines for a wide variety of pathoge... | 02/28/2012 |
| 8124180 | Thin layer substrate coating and method of forming same Embodiments of the present invention relate to coating deposition and coatings for dental and orthopedic devices that provide prevention or reduction of ion leakage and, in some situations, improved aesthetic appearances. ... | 02/28/2012 |
| 8101192 | Methods for producing an immune response to tuberculosis Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb,... | 01/24/2012 |
| 8097428 | Monoclonal antibodies and their use Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic endocrine cells or a subset thereof, and/or a precursor thereof. Isolated monoclonal antibodies are also disclosed herein that specifi... | 01/17/2012 |
| 8093216 | Method of treating cancer by inhibition of p95HER-2 production There is disclosed an initial identification of an N-terminally truncated HER-2/neu product. This product is a 95 kDa polypeptide having in vitro kinase activity (as determined by western blotting). Moreover, immunoprecipitations using domain specific antibodies was... | 01/10/2012 |
| 8071553 | Method and peptide for regulating cellular activity Method and peptide for regulating cellular activity includes a panel of synthesized peptides that have biological effects on inhibiting or enhancing cellular activity. Selected peptides can be used as therapy to reduce and/or inhibit, or initiate and/or enhance, an ... | 12/06/2011 |
| 8053197 | Methods for detecting and treating autoimmune disorders The present disclosure relates to methods for inhibiting an autoimmune disease by administering to a subject a therapeutically effective amount of a composition that increases FOXP3 expression, thereby inhibiting the autoimmune disease. Further disclosed herein are ... | 11/08/2011 |
| 8053181 | Methods for detecting a infection Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed. The methods include detecting the presence of CD8+T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting th... | 11/08/2011 |
| 8030004 | Cell free screening assay and methods of use Methods are disclosed for identifying agents for the treatment of cancer and/or Fanconi anemia using Xenopus egg cell free extracts from which the endogenous DNA has been removed. The assays and method described herein are easily adaptable to high throughput ... | 10/04/2011 |
| 8003674 | Flavivirus inhibition by sultams and related compounds Disclosed herein are compounds, compositions and methods for treating or ameliorating flavivirus infections. This is particularly important because the present disclosure provides methods for treating flavivirus infections for which there is no effective vaccine. | 08/23/2011 |
| 7981628 | Monoclonal antibodies and their use Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic endocrine cells or a subset thereof, and/or a precursor thereof. Isolated monoclonal antibodies are also disclosed herein that specifi... | 07/19/2011 |
| 7972849 | Primate pluripotent stem cells produced by somatic cell nuclear transfer Purified totipotent stem cells and pluripotent stems cells derived by somatic cell nuclear transfer are disclosed herein, as well as cell lines, multipotent cells and differentiated cells produced from these stem cells. The stem cells are produced from an enucleated... | 07/05/2011 |
| 7972607 | Attenuated francisella and methods of use Francisella tularensis is the bacterial pathogen that causes tularemia in humans and a number of animals. To date, no approved vaccine exists for this widespread and life-threatening disease. The present disclosure provides attenuated Francisella mutan... | 07/05/2011 |
| 7968682 | Degradation-resistant fibrinogen sealants Provided are degradation-resistant fibrinogen sealants comprising a first composition comprising one or more of fibrinogen γA/γ′ heterodimers and/or fibrinogen γ′/γ′ homodimers and a second composition comprising thrombin and, optionally, degradation-resis... | 06/28/2011 |
| 7943296 | Methods of screening using a natriuretic peptide receptor This disclosure provides an intracellular fragment of natriuretic peptide receptor A (NPRA), referred to herein as soluble natriuretic peptide receptor-related fragment (sNRF). It is shown herein that sNRF causes NP resistance. Based on these observations, methods o... | 05/17/2011 |
| 7939080 | HER-2 binding antagonists There is disclosed a pharmaceutical composition for treating solid tumors that overexpress HER-2, comprising an agent selected from the group consisting of (a) an isolated polypeptide having from about 50 to 79 amino acids taken from the sequence of SEQ ID NO:1, whe... | 05/10/2011 |
| 7930025 | Ventricular tachyarrhythmia prediction and/or prevention Embodiments of the present invention provide apparatuses and methods to predict and/or prevent episodes of ventricular tachyarrhythmia (for example, ventricular tachycardia and/or ventricular fibrillation). A method is provided for predicting an episode of ventricul... | 04/19/2011 |
| 7919329 | Method for screening for agents that affect food intake Screening methods of use in identifying agents that affect caloric intake, food intake, appetite, and energy expenditure are disclosed herein. These methods are used to identify agents of use in treating obesity, or that can be used to decrease the weight of a subje... | 04/05/2011 |
| 7914567 | Stent tissue graft prosthesis A stent tissue graft prosthesis (20) for repairing, excluding and/or reinforcing a vessel, duct and the like in a patient. The prosthesis includes an inner expandable stent (21) of which a tissue graft (24) and preferably a multilayered tissue c... | 03/29/2011 |
| 7875710 | Nucleic acids encoding platelet derived growth factor receptor alpha (PDGFRA) activating mutations This disclosure provides tyrosine kinase protein and nucleic acid variants, particularly PDGFRA variants, which are activating forms of these molecules and are linked to neoplasms and/or the development or progression of cancer. The disclosure further provides metho... | 01/25/2011 |
| 7871430 | Medical device delivery system A delivery system (10) for implanting a medical device (30) such as a venous valve into the vasculature of a patient. The delivery system includes a delivery catheter (11) having a device-containing portion (15) adjacent to the distal end... | 01/18/2011 |
| 7842470 | Method for pharmacoperones correction of GnRHR mutant protein misfolding This application relates to methods of identifying pharmacoperone agents that can restore function to a misfolded protein, such as a misfolded protein that causes disease. Also disclosed are methods of using such pharmacoperone agents to treat a disease or disorder ... | 11/30/2010 |
| 7842299 | Methods for producing an immune response to tuberculosis Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional embodiments, methods are disclosed for preventing an infection with Mtb,... | 11/30/2010 |
| 7829578 | Aromatic ketones and uses thereof Aromatic ketones having an extended fluoro-alkyl or fluoro-alkoxy moiety are disclosed. In particular aspects, the compounds comprise substituted 9-acridone, 9-xanthone, 4(1H)-quinolone, 4(1H) pyridone, 1,4-naphthoquinone, 9,10-anthraquinone derivatives. These prepa... | 11/09/2010 |
| 7814590 | Accessory panel for diagnostic platform, patient bed and other support surfaces Embodiments herein provide a flexible accessory panel with apertures from which items may be suspended. In particular, receptacles for fluids draining from a patient may be suspended from the apertures, which are retained at a level below that of the patient, mainta... | 10/19/2010 |
| 7745604 | Upstream control elements of the proopiomelanocortin gene and their use The nucleic acid sequence of the POMC enhancer is disclosed herein. Sequences from the human, rat, rabbit, hamster, mouse, and cow POMC enhancer are disclosed. Hybrid transgenes, comprising a POMC transcriptional control element operably linked to a nucleic acid seq... | 06/29/2010 |
| 7727162 | Bias-probe rotation test of vestibular function Apparatus and methods for rotation test stimulus and analysis methods overcome many of the limitations of traditional clinical tests of peripheral vestibular function. An embodiment includes a rotational stimuli applied to the rotational motion for testing that incl... | 06/01/2010 |
| 7714102 | Mutant IGFBP-3 molecules that do not bind to IGFs, but retain their ability to functionally bind IGFBP-3 receptor There is disclosed novel mutant IGFBP-3 polypeptides and fragments thereof that have either no binding, or diminished binding to IGFs, yet retain their ability to bind to the human IGFBP-3 receptor (“P4.33”). The present invention provides novel mutant IGFBP-3 n... | 05/11/2010 |
| 7695917 | Rescue of gonadotropin releasing hormone receptor mutants Herein disclosed is a method of rescuing gonadotropin-releasing hormone receptor (GnRHR) mutants with IN3 or a mimetic thereof. IN3 significantly rescues 11 missense mutations as assessed by radioligand binding and by IP production. Such rescue occurred despite wide... | 04/13/2010 |
| 7625859 | HER-2 binding antagonists There is disclosed a pharmaceutical composition for treating solid tumors that overexpress HER-2, comprising an agent selected from the group consisting of (a) an iso lated polypeptide having from about 50 to 79 amino acids taken from the sequence of SEQ ID NO. 1, w... | 12/01/2009 |
| 7615527 | Peptides which modulate blood coagulation and methods of use thereof Peptide fragments that modulate thrombosis and methods of use thereof are provided. Also provided are synthetic bioactive anti-coagulation peptides, compositions comprising such peptides and methods for the administration to patients in need thereof. ... | 11/10/2009 |
| 7585497 | Induction of apoptosis and cell growth inhibition by protein 4.33 There is disclosed an isolated cDNA sequence (SEQ ID NO:1) encoding a P4.33 polypeptide and comprising a coding region (SEQ ID NO:2) of the sequence described in SEQ ID NO:1, or a sequence having at least 90% homology with the coding region of SEQ ID NO:1. The P4.33... | 09/08/2009 |
| 7566311 | Device for rehabilitation of individuals experiencing loss of skeletal joint motor control with passive range-of-motion pivoting mechanism and vibrator system A method and device for the rehabilitation of patients that have suffered loss of motor control of an appendicular joint due to neurological damage. The method includes attempted contraction by a patient of a muscle that serves to move an affected joint coupled with... | 07/28/2009 |
| 7563234 | Electromyographic (EMG) feedback during AMES treatment of individuals with severe neuromuscular deficits A method of rehabilitating a patient suffering partial or total loss of motor control of an appendicular joint caused by injury or neurological disorder but exhibiting clinically plegic (i.e., paralyzed) muscles and retaining minimal ability to weakly contract the m... | 07/21/2009 |
| 7557197 | Human soluble neuropilin-1 primary polyadenylation signal and uses thereof The human soluble neuropilin-1 (sNRP) polyadenylation signal (sNRP-poly(A)), situated downstream of the GT splice donor site of intron 12 of the full-length neuropilin-1 gene, also functions as the termination codon for sNRP. This 17 nucleotide sequence efficiently ... | 07/07/2009 |
| 7520894 | Implantable vascular device A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The ... | 04/21/2009 |
| 7514532 | Mutant IGFBP-3 molecules that do not bind to IGFS, but retain their ability to functionally bind IGFBP-3 receptor There is disclosed novel mutant IGFBP-3 polypeptides and fragments thereof that have either no binding, or diminished binding to IGFs, yet retain their ability to bind to the human IGFBP-3 receptor (“P4.33”). The present invention provides novel mutant IGFBP-3 n... | 04/07/2009 |
