Assignee: Oregon Health Sciences University

Location: Portland, OR
No. of patents: 70

Number	Title	Issue Date
7686842	Endovascular stent graft A stent graft (10) with a stent frame (12) having a plurality of stents (16) connected together with monofilament line (22). A covering (14) of collagen having an extracellular matrix (ECM), such as small intestine submucosa (SIS),...	03/30/2010
7396810	Compositions and methods for treating cancer by modulating HER-2 and EGF receptors An alternative HER-2/neu product, herstatin, consists of subdomains I and II from the ectodomain of p185HER-2 and a unique 79 amino acid C-terminus encoded by intron 8. Recombinant herstatin added to cells was found to bind to and inhibit p185HER-2. The effects of e...	07/08/2008
7384913	PT32 sperm protein, sperm c-Yes, oocyte cytoplasmic c-Yes, and uses thereof The perinuclear theca 32 (PT32) protein is disclosed and shown to interact with tyrosine kinase c-Yes. PT32, c-Yes, fragments thereof, and molecules that bind thereto can be used in methods of enhancing fertility, treating or diagnosing diminished fertility and abno...	06/10/2008
7351534	Gene mutation associated with age-related macular degeneration The present invention describes the identification of a mutation in a human FIBL-6 protein, which mutation is associated with Familial Age-Related Macular Degeneration. Transcripts and products of this mutated gene are useful in detecting and diagnosing AMD, develop...	04/01/2008
7282340	Methods for identifying an analog that promotes nerve regeneration Analogs of FK506 that do not bind FKBP-12 have been found to effectively promote nerve cell growth and regeneration, thereby speeding functional recovery of damaged nervous tissue and axonal regeneration without causing immunosuppression. ...	10/16/2007
7214528	Device for direct electrical detection of molecules and molecule-molecule interactions An analysis device includes an electrode arrangement, a current/voltage provider, and a circuit analyzer. The electrode arrangement has an interdigitated electrode pair including a first electrode and a second electrode. Coupled to the electrode arrangement is a sig...	05/08/2007
7053189	Human dopamine receptor and its uses The present invention is directed toward antibodies, particularly monoclonal antibodies, which bind specifically to a novel human D4 dopamine receptor in sensitive and specific immunological assays useful for the detection, quantization, and characterization of huma...	05/30/2006
7026451	Small and intermediate conductance, calcium-activated potassium channels and uses thereof This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically the invention relates to compositions and methods for making and detecting calcium-activated potassium channel proteins and the nucleic acid...	04/11/2006
6987169	Small conductance, calcium-activated potassium channels (SK 3) This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium-activated potassium channel proteins and the nucleic aci...	01/17/2006
6894147	Intermediate conductance calcium-activated potassium channels (IK1) This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium-activated potassium channel proteins and the nucleic aci...	05/17/2005
6828122	Nucleic acid encoding small conductance calcium-activated potassium channel (SK1) This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium-activated potassium channel proteins and the nucleic aci...	12/07/2004
6828123	Small DNA encoding conductance, calcium-activated potassium channels (SK3) This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium-activated potassium channel proteins and the nucleic aci...	12/07/2004
6828420	Small conductance, calcium-activated potassium channels (SKI) This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium-activated potassium channel proteins and the nucleic aci...	12/07/2004
6797486	Small and intermediate conductance, calcium-activated potassium channels and uses thereof This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium-activated potassium channel proteins and the nucleic aci...	09/28/2004
6734211	Compositions and methods for promoting nerve regeneration Neurite outgrowth and nerve regeneration are promoted by disruption of the steroid receptor complex and stimulation of MAP kinase/kinase activity. This disruption can take the form of disruption of the physical assembly or function of the steroid receptor complex, s...	05/11/2004
6558911	Sperm quality assay The present invention relates to male infertility, and in particular to assays for predicting fertility in animals including human and bovines. In some embodiments, semen samples are evaluated by measuring the amount of ubiquitin in the sample, and in par...	05/06/2003
6538108	Compositions and methods relating to DNA mismatch repair genes Genomic sequences of human mismatch repair genes and gene products are described, as are methods of detecting mutations and/or polymorphisms in those genes. Also described are methods of diagnosing cancer susceptibility in a subject, and methods of identi...	03/25/2003
6537803	Amino acid transporters and uses The present invention relates to novel mammalian amino acid transporter proteins and the genes that encode such proteins. The invention is directed toward the isolation, characterization and pharmacological use of the human amino acid transporter proteins...	03/25/2003
6476187	Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals The present invention provides recombinant expression constructs comprising nucleic acid encoding mammalian melanocortin receptors, and mammalian cells into which said recombinant expression constructs have been introduced that express functional mammalia...	11/05/2002
6451528	Sperm-specific AKAP protein genes and uses This invention provides isolated nucleic acid encoding sperm-specific protein kinase A anchoring proteins from mammalian species, recombinant expression constructs encoding said mammalian sperm-specific protein kinase A anchoring proteins, cells transform...	09/17/2002
6451993	Polynucleotides encoding human excitatory amino acid transporter 4 (EAAT4) The present invention relates to novel mammalian amino acid transporter proteins and the genes that encode such proteins. The invention is directed toward the isolation, characterization and pharmacological use of a human amino acid transporter protein te...	09/17/2002
6423738	Methods for treating circadian rhythm phase disturbances A method for treating circadian rhythm phase disorders is described. The invention provides methods to specifically advance or delay the phase of certain circadian rhythms in humans. The disclosed methods relate to the administration of melatonin at times...	07/23/2002
6420121	Prevention of cell migration initiation with CMV US28 receptor antagonists There is disclosed an assay system for determining therapeutic activity for treating restenosis, atherosclerosis, chronic rejection syndrome and graft versus host disease (GVHD) by measuring inhibition of cell migration activity in smooth muscle cells exp...	07/16/2002
6406866	Method of screening of a compound for binding to MSOR The present invention relates to a novel mammalian opioid receptor protein and ligands that bind to such proteins. The invention is directed toward the isolation, characterization and pharmacological use of an endogenous ligand that specifically binds to ...	06/18/2002
6277382	Hemoglobin receptors from neisseriae The present invention relates to novel bacterial hemoglobin receptor proteins and genes that encode such proteins. The invention is directed toward the isolation, characterization, diagnostic and therapeutic use of bacterial hemoglobin receptor proteins, ...	08/21/2001
6270772	Recombinant MHC molecules useful for manipulation of antigen-specific T-cells Two-domain MHC polypeptides useful for manipulation of antigen-specific T-cells are disclosed. These polypeptides include MHC class II-based molecules that comprise covalently linked 댡 and 댑 domains, and MHC class I-based molecules that comp...	08/07/2001
6225048	Dendritic-marker expressing macrophage cultures and methods of reactivating latent virus The present invention provides methods of latent virus reactivation in monocyte-derived macrophages through allogeneic stimulation of peripheral blood mononuclear cells ("PBMC"), methods of culturing virus, and cultures of virally permissive monocyte-deri...	05/01/2001
6210974	Compositions and methods for promoting nerve regeneration FK506 and geldanamycin promote nerve regeneration by a common mechanism that involves the binding of these compounds to polypeptide components of steroid receptor complexes other than the steroid hormone binding portion of the complex (FKBP52 and hsp90, r...	04/03/2001
6203998	Human dopamine receptor and its uses The present invention is directed toward isolation, characterization and pharmacological use of the human D4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor and alleleic variant thereof are provided by the invention. ...	03/20/2001
6191268	Compositions and methods relating to DNA mismatch repair genes Genomic sequences of human mismatch repair genes are described, as are methods of detecting mutations and/or polymorphisms in those genes. Also described are methods of diagnosing cancer susceptibility in a subject, and methods of identifying and classify...	02/20/2001
6165713	Composition and methods relating to DNA mismatch repair genes Genomic sequences of human mismatch repair genes are described, as are methods of detecting mutations and/or polymorphisms in those genes. Also described are methods of diagnosing cancer susceptibility in a subject, and methods of identifying and classify...	12/26/2000
6137291	Telescoping coil array for magnetic resonance imaging of extremities An MR coil array includes a plurality of telescopically arranged coil units, spanning the length of an extremity (e.g. a leg). The coil in each unit encircles the extremity, providing good SNR from all sides and for deep structures as well. The tapered sh...	10/24/2000
6133236	Products and methods for improving keratinocyte adhesion to the dermis Improving adhesion of epidermis to an underlying dermal substrate including the step of providing an amount of purified kalinin between the epidermis and dermal substrate wherein the kalinin provides adhesion between the human dermis and epidermis wherein...	10/17/2000
6132708	Liver regeneration using pancreas cells This invention provides a method of regenerating a functional liver by transplantation of pancreas cells. Also provided are pancreas cell capable of regenerating functional liver tissue....	10/17/2000
6123942	Bacterial hemoglobin receptor gene The present invention relates to a novel bacterial hemoglobin receptor protein and genes that encode such a protein. The invention is directed toward the isolation, characterization, diagnostic and therapeutic use of a bacterial hemoglobin receptor protei...	09/26/2000
6100085	Amino acid transporters and uses The present invention relates to novel mammalian amino acid transporter proteins and the genes that encode such proteins. The invention is directed toward the isolation, characterization and pharmacological use of the human amino acid transporter proteins...	08/08/2000
6100048	Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals The present invention provides recombinant expression constructs comprising nucleic acid encoding mammalian melanocortin receptors, and mammalian cells into which said recombinant expression constructs have been introduced that express functional mammalia...	08/08/2000
6090560	Amino acid transporters and uses The present invention relates to novel mammalian amino acid transporter proteins and the genes that encode such proteins. The invention is directed toward the isolation, characterization and pharmacological use of a human amino acid transporter protein te...	07/18/2000
6074828	Amino acid transporters and uses The present invention relates to novel mammalian amino acid transporter proteins and the genes that encode such proteins. The invention is directed toward the isolation, characterization and pharmacological use of the human amino acid transporter proteins...	06/13/2000
6069164	Methods for treating circadian rhythm phase disturbances A method for treating circadian rhythm phase disorders is described. The invention provides methods to specifically advance or delay the phase of certain circadian rhythms in humans. The disclosed methods relate to the administration of melatonin at times...	05/30/2000

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Assignee: Oregon Health Sciences University