...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 7894645 | High-resolution digital image processing in the analysis of pathological materials A method and system of ascertaining diagnostic information concerning a pathological specimen over a network is disclosed. The method comprises transmitting a digitized image of a pathological specimen to central location, and then receiving diagnostic information f... | 02/22/2011 |
| 7893616 | Process to determine enzyme activity The present invention provides for various processes for determining enzyme activity. In one embodiment, a process for detecting an enzyme activity includes contacting a blood component with a substrate comprising a cleavage site of the enzyme and a tag moiety to pr... | 02/22/2011 |
| 7705996 | Methods and systems for ultra-precise measurement and control of object motion in six degrees of freedom by projection and measurement of interference fringes A system and method for active visual measurement and servo control using laterally sampled white light interferometry (L-SWLI) for real-time visual tracking of six-degree-of-freedom (6 DOF) rigid body motion with near-nanometer precision. The visual tracking system... | 04/27/2010 |
| 6440673 | Methods for identifying nucleic acid mutations using mismatch modification The present invention provides methods for specifically detecting DNA mismatches between heteroduplex strands produced between wildtype and mutation containing nucleic acid species. Kits for performing the methods of the invention are also provided.... | 08/27/2002 |
| 6082205 | System and device for determining particle characteristics The present invention provides methods and apparatuses for determining at least one of a plurality of particle physical characteristics. The particle physical characteristics include particle size, shape, magnetic susceptibility, magnetic label density, c... | 07/04/2000 |
| 6080544 | Methods for identifying nucleic acid mutations using mismatch modification The present invention provides methods for specifically detecting DNA mismatches between heteroduplex strands produced between wildtype and mutation containing nucleic acid species. Kits for performing the methods of the invention are also provided.... | 06/27/2000 |
| 5994246 | Low expansion feldspathic porcelain A feldspathic porcelain composition is provided which comprises a continuous glassy matrix phase and a discontinuous, substantially uniformly dispersed cubic leucite crystalline phase, said composition possessing a fusion temperature of from about 800° t... | 11/30/1999 |
| 5585439 | Modification of unsaturated polyester resins for viscosity control An unsaturated polyester resin and low profile additive containing diketo groups.... | 12/17/1996 |
| 5552156 | Liposomal and micellular stabilization of camptothecin drugs The present invention provides water soluble, stable, highly pharmacologically active camptothecin drugs by solubilizing the camptothecin drugs in liposomes composed of lipids or in micelles composed of surfactants. The invention overcomes both the insolu... | 09/03/1996 |
| 5468499 | Liposomes containing the salt of phosphoramide mustard and related compounds The present invention provides an anti cancer treatment which has an improved stability and does not produce acrolein. The invention includes dichlorodiethyl phosphoramide drugs including, for example, the cyclohexylamine salt phosphoramide mustard and is... | 11/21/1995 |
| 5336796 | Diastereomeric mono- and di-substituted diamino cyclohexane compounds and the method of preparation thereof One aspect of the present invention relates to a process of making cyclohexane-1,2-di(O)-4,5-di(N) diastereomers which are useful as a synthons for various diastereoisomeric pharmaceutical systems. The present invention also relates to the stereoisomer co... | 08/09/1994 |
| 5317279 | Linear voltage to current converter including feedback network A voltage to current converter includes three field effect transistors (FETs), the sources of which are electrically connected to define a common source node, and a feedback network. First and second voltage inputs are connected to the gates of the first ... | 05/31/1994 |
| 5226933 | Pressure swing adsorption system to purify oxygen A pressure swing adsorption (PSA) process for splitting oxygen from a feed gas comprising 95% oxygen and 5% argon to achieve an oxygen purity of at least about 99.7% is provided. A column used in the PSA process includes therein a bed of silver mordenite,... | 07/13/1993 |
| 5208599 | Serrated electromagnetic absorber Electromagnetic absorber having serrations on a surface or surfaces thereof to reduce reflectivity of incident electromagnetic waves thereon. The serrations form a plurality of fins, the height of adjacent fins being spaced by a small distance. Preferably... | 05/04/1993 |
| 5206400 | Diastereomeric mono- and di-substituted diamino cyclohexane compounds and the method of preparation thereof One aspect of the present invention relates to a process of making cyclohexane-1,2-di(O)-4,5-di(N) diastereomers which are useful as a synthons for various diastereoisomeric pharmaceutical systems. The present invention also relates to the stereoisomer co... | 04/27/1993 |
| 5148807 | Non-contact tonometer A non-contact, non-invasive tonometer utilizing the technique of angle modulation of high frequency sound waves or high frequency light waves to determine the intraocular pressure of an eye. The angle modulation technique can be either frequency modulatio... | 09/22/1992 |
| 5130426 | Synthesis of bis (morpholinomethyl) derivatives of tricyclic bis (dioxopiperazines) Bis(morpholinomethyl) derivatives of tricyclic bisdioxopyperzaines of the formula ##STR1## wherein R is H, ##STR2## R' is H, lower alkyl groups (straight or branched chain of 1 to 6 carbon atoms) and the processes for the syntheses thereof ... | 07/14/1992 |
| 4950755 | Bis(morpholinomethyl) derivative of 1,2-bis(dioxopiperizinyl)propane Bis(morpholinomethyl) derivative of 1,2-bis(dioxopiperizinyl)propane of the formula: ##STR1## wherein R is CH3, R' is ##STR2## and the process for the synthesis thereof is provided. The compound of the present invention is water ... | 08/21/1990 |
| 4691006 | Antigenic modification of polypeptides Endogenous and exogenous proteins, and fragments thereof, are chemically modified outside the body of an animal so that when injected into the animal they produce more antibodies against the unmodified protein than would injection of the unmodified protei... | 09/01/1987 |
| 4687733 | Early cancer detection method The invention relates to a method of testing for the presence of cancer. An antibody is produced which contains antibodies specific to a modified nucleoside component. The antibody is admixed with a body fluid drawn from a subject mammal. An immunoassay i... | 08/18/1987 |
| 4676733 | Method for producing a clean heated fluid The invention relates to a method for combusting a dirty and/or difficult to burn fuel in a fluidized bed combustor. The fluidized bed and freeboard zone of the combustor are cooled by a non-intrusive counterflow cooling system which controls combustion t... | 06/30/1987 |
| 4671251 | Fluidized bed combustor The invention relates to a method and apparatus for combusting a dirty and/or difficult to burn fuel in a fluidized bed combustor. The fluidized bed and freeboard zone of the combustor are cooled by a non-intrusive counterflow cooling system which control... | 06/09/1987 |
| 4657067 | Hypereutectic direct-contact thermal storage material and method of production thereof An improved particle, and process for producing particle, for use in the storage and retrieval of thermal energy is disclosed. The particle comprises a eutectic material core encapsulated within a high-melting, corrosion resistant material.... | 04/14/1987 |
| 4654005 | Leaf gage and wafer A dental apparatus for use in efficiently obtaining an accurate relationship of upper and lower jaws of a dental patient which includes a wafer and a leaf gage. The wafer is made of a substantially stable but vertically deformable material and has a gener... | 03/31/1987 |
| 4537882 | 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same Compounds of the formula (I), acid addition salts thereof, and pharmaceutical preparations containing the same are disclosed ##STR1## wherein R1 is hydroxy; one of X and X' is hydrogen and the other is a halogen atom selected from the grou... | 08/27/1985 |