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Assignee: Nycomed Salutar Inc.


Location: Sunnyvale, CA
No. of patents: 8

NumberTitleIssue Date
5869651Hydrazide derivatives of polyamides and their medical use as chelating agents
The invention relates to certain substituted derivatives of aminopolycarboxylic acids and metal chelates thereof. The compounds are particularly suitable for use as diagnostic agent. For example, the compounds can be used as radiodiagnostic agents, detoxi...
02/09/1999
5688486Use of fullerenes in diagnostic and/or therapeutic agents
Compounds including tight molecular meshes, preferably curved in one or two directions, such as fullerenes and met-cars, can be used as carriers for diagnostic or therapeutic agents, especially diagnostic contrast agents....
11/18/1997
5650133Macrocyclic polyaza dichelates linked through ring nitrogens via an amide or ester functionality
This invention relates to dichelants, in particular compounds having two macrocyclic chelant groups linked by a bridge containing an ester or amide bond, especially compounds of formula Vb ##STR1## (wherein each X which may be the same or different i...
07/22/1997
5614168Multinuclear complexes for X-ray imaging
The invention relates to the use as contrast enhancing agents in medical imaging, especially X-ray imaging, of multinuclear complexes, i.e. complexes, such as those of W202 (U20) 2, in which the complexed entity comprises at least two contrast enhancing a...
03/25/1997
5556968Polyazamacrocycle chelating agents with amide linkages
Macrocyclic chelating agents, optionally possessing more than one macrocyclic ring having at least two peptide linkages within the macrocyclic skeleton. The chelating agents are used for the preparation of paramagnetic metal chelates for use as MRI contra...
09/17/1996
5482699Multinuclear complexes for x-ray imaging
An imaging contrast medium comprising a physiologically tolerable multinuclear complex (as defined in claim 1) is disclosed. The multinuclear complex contains at least two, but preferably three or more contrast enhancing atoms. For X-ray or ultrasound ima...
01/09/1996
5458869Multinuclear complexes for X-ray imaging
The invention relates to the use as contrast enhancing agents in medical imaging, especially X-ray imaging, of multinuclear complexes, i.e. complexes, such as those of W2O2 (u2O)2, in which the complexed entity comprises at least two contrast enhancing at...
10/17/1995
5446145Polychelant compounds
There are disclosed polychelant compounds, that is multi-site metal chelating agents, and chelates formed therewith. The polychelants and especially their paramagnetic metal, heavy metal or radioactive metal polychelates are particularly suitable for use ...
08/29/1995
 
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