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Assignee: Nycomed GmbH


Location: Constance, DE
No. of patents: 39

NumberTitleIssue Date
8182824Ciclesonide-containing sterile aqueous suspension
The present invention provides a ciclesonide-containing sterile aqueous suspension sterilized by autoclaving, wherein the concentration of ciclesonide after autoclaving is 95% or more compared to that before autoclaving. ...
05/22/2012
8163299Stabilized pharmaceutical product
Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar. ...
04/24/2012
8106047Triazolophthalazines
The compounds of formula (I) in which R1, R2 and R3 have the meanings as given in the description are novel effective PDE2 inhibitors. ...
01/31/2012
8029811Stabilized pharmaceutical product
Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar. ...
10/04/2011
8017633Roflumilast for the treatment of diabetes mellitus
The invention relates to the use of Roflumilast and/or Roflumilast N-Oxide for the treatment of diabetes mellitus and accompanying disorders thereof. The invention additionally relates to combinations of Roflumilast and/or Roflumilast N-Oxide with other active agent...
09/13/2011
8003798Hydroxy-6-heteroarylphenanthridines and their use as PDE4 inhibitors
Compounds of the formula I in which the substituents have the definitions provided in the specification, are novel, effective PDE4 inhibitors. ...
08/23/2011
7988999Pharmaceutical preparation in the form of a paste comprising an acid-labile active ingredient
The present invention relates to the field of pharmaceutical technology and describes a pharmaceutical preparation in the form of a paste comprising an acid-labile active ingredient, in particular an acid-labile proton pump inhibitor. The invention also relates to p...
08/02/2011
7951398Pharmaceutical preparation comprising an active dispersed on a matrix
The present invention relates to the field of pharmaceutical technology and describes a novel advantageous preparation for an active ingredient. The novel preparation is suitable for producing a large number of pharmaceutical dosage forms. In the new preparation, an...
05/31/2011
7951397Oral dosage form containing a PDE 4 inhibitor as an active ingredient and polyvinylpyrrolidon as excipient
Dosage forms for oral administration of a PDE 4 inhibitor whose solubility is slight are described. They contain PVP as binder. ...
05/31/2011
7947744Stable pharmaceutical products
Provided herein is a stable pharmaceutical product comprising a dry powder inhalation device, and a pharmaceutical composition that comprises R,R-Formoterol L-tartrate salt, in particular crystalline R,R-formoterol L-tartrate; and ciclesonide. ...
05/24/2011
7879833Combination medicament
The invention relates to the combination of ciclesonide with formoterol. ...
02/01/2011
7851472Triazolophthalazines
The compounds of formula I in which R1 and R2 have the meanings as given in the description are novel effective PDE2 inhibitors. ...
12/14/2010
78385213-oxa-10-aza-phenanthrenes
The compounds of formula I in which R1, R2 and R3 have the meanings as given in the description, are novel effective PDE4 inhibitors. ...
11/23/2010
78206692-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors. ...
10/26/2010
7794752Preparation and administration form comprising an acid-labile active compound
Novel administration forms and preparations for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprisi...
09/14/2010
7790710Imidazopyridine derivatives useful as iNOS inhibitors
The compounds of formula (I) in which R1, R11 and A have the meanings as given in the description are novel effective iNOS inhibitors. ...
09/07/2010
7790198Preparation and administration form comprising an acid-labile active compound
Novel administration forms and preparation for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprisin...
09/07/2010
7785630Preparation and administration form comprising an acid-labile active compound
Novel administration forms and preparation for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprisin...
08/31/2010
7776893Use of PDE4 inhibitors for the treatment of diabetes mellitus
The invention relates to the use of certain known PIDE4 inhibitors for the treatment of diabetes mellitus and accompanying disorders thereof. ...
08/17/2010
7736673Stabilized pharmaceutical product
The invention relates to the use of an adsorbent and a sealed package, for example an overwrap, to protect a pharmaceutical product in a solid state in the presence of a reducing sugar. ...
06/15/2010
7718668Salts of 6-heterocycle substituted hexahydrophenanthridine derivatives
The invention relates to salts of 6-heteroaryl substituted hexahydrophenanthridine PDE4-inhibiting compounds, which can be used in the pharmaceutical industry for the production of pharmaceutical compositions for use, e.g., in treatment of airway disorders. ...
05/18/2010
7671050Triazolophthalazines
The compounds of formula (I) in which R1, R2 and R3 have the meanings as given in the description are novel effective PDE2 inhibitors. ...
03/02/2010
7666872Use for PDE5 inhibitors
The present invention is concerned with the use of PDE5 inhibitors in medicine. ...
02/23/2010
7641050Medicine pack
The present invention relates to a novel type of medicine pack comprising a plurality of blister units (1), said blister units (1) each having a protective case (6), with a blister strip (4) located therein, the blister strip (4) b...
01/05/2010
76328442-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors
The compounds of formula I in which R1, R2, R3, R31, R4, R5, R6 and R7 have the meanings as indicated in the description, are novel effective PDE4 inhibitors. ...
12/15/2009
7629361Salt of (S)-pantoprazole and its hydrates
The invention relates to (−)-pantoprazole magnesium and its hydrates and to medicaments comprising these compounds. ...
12/08/2009
7601737Isotopically substituted proton pump inhibitors
The invention relates to compounds of formula 1 and formula 10 and to compositions comprising these compounds and methods of treating gastrointestinal disorders by administering t...
10/13/2009
7585872Guanidinyl-substituted hydroxy-6-phenylphenanthridines as effective phosphodiesterase (PDE) 4 inhibitors
The compounds of a certain formula (1), in which R1, R2, R3, R31, R4, R5, R6 and R7 have the meanings as given in the description, are novel effective PDE4 inhibitors. ...
09/08/2009
74949902-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors
The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors. ...
02/24/2009
7470704Benzonaphthyridines
The compounds of formula I in which R1, R2, R3, R4, R5, R6 and n have the meanings as indicated in the description, are novel effective PDE3/4 inhibitors. ...
12/30/2008
7468433Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21-dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation
The invention relates to a process for the preparation of 16,17-[(cyclohexylmethylene)bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione[11β,16α(R)] and similar compounds, by reaction of an appropriate 16,17-ketal with cyclohexanealdehyde. ...
12/23/2008
7452998Process for preparing optically pure active compounds
The invention relates to a novel process for preparing an optically pure PPI having a sulfinyl structure using a chiral zirconium complex or a chiral hafnium complex. ...
11/18/2008
D580547Tablet
11/11/2008
74230463-hydroxy-6-phenylphenanthridines as pde-4 inhibitors
Compounds of formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meaning indicated in the description, are novel effective PDE4 inhibitors. ...
09/09/2008
7402321Oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles
The invention relates to an oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles and their salts, which comprises the active compound together with tablet disintegrants and is provided with a film coating customary per se for sustained-release c...
07/22/2008
7357943Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient
The present invention relates to the field of pharmaceutical technology and describes a novel pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient, in particular an acid-labile proton pump inhibitor. The invention also r...
04/15/2008
7351723Freeze-dried pantoprazole preparation and pantoprazole injection
Lyophilized pantoprazole preparations which are obtainable by freeze-drying of an aqueous solution of pantoprazole, ethylenediamine tetraacetic acid and/or a suitable salt thereof, and sodium hydroxide and/or sodium carbonate are disclosed. The preparations have adv...
04/01/2008
73296762-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors
The compounds of formula I in which R1, R2, R3, R31, R4, R5, R6 and R7 have the meanings as indicated in the description, are novel effective PDE4 inhibitors. ...
02/12/2008
7279488Imidazopyridine-derivatives as inducible no-synthase inhibitors
The compounds of Formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors. ...
10/09/2007
 
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