Penn Jillette of Penn and Teller fame has patented a "Hydro-Therapeutic Stimulator", which uses a hot tub for stimulation.
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| Number | Title | Issue Date |
| 8182824 | Ciclesonide-containing sterile aqueous suspension The present invention provides a ciclesonide-containing sterile aqueous suspension sterilized by autoclaving, wherein the concentration of ciclesonide after autoclaving is 95% or more compared to that before autoclaving. ... | 05/22/2012 |
| 8163299 | Stabilized pharmaceutical product Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar. ... | 04/24/2012 |
| 8106047 | Triazolophthalazines The compounds of formula (I) in which R1, R2 and R3 have the meanings as given in the description are novel effective PDE2 inhibitors. ... | 01/31/2012 |
| 8029811 | Stabilized pharmaceutical product Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar. ... | 10/04/2011 |
| 8017633 | Roflumilast for the treatment of diabetes mellitus The invention relates to the use of Roflumilast and/or Roflumilast N-Oxide for the treatment of diabetes mellitus and accompanying disorders thereof. The invention additionally relates to combinations of Roflumilast and/or Roflumilast N-Oxide with other active agent... | 09/13/2011 |
| 8003798 | Hydroxy-6-heteroarylphenanthridines and their use as PDE4 inhibitors Compounds of the formula I in which the substituents have the definitions provided in the specification, are novel, effective PDE4 inhibitors. ... | 08/23/2011 |
| 7988999 | Pharmaceutical preparation in the form of a paste comprising an acid-labile active ingredient The present invention relates to the field of pharmaceutical technology and describes a pharmaceutical preparation in the form of a paste comprising an acid-labile active ingredient, in particular an acid-labile proton pump inhibitor. The invention also relates to p... | 08/02/2011 |
| 7951398 | Pharmaceutical preparation comprising an active dispersed on a matrix The present invention relates to the field of pharmaceutical technology and describes a novel advantageous preparation for an active ingredient. The novel preparation is suitable for producing a large number of pharmaceutical dosage forms. In the new preparation, an... | 05/31/2011 |
| 7951397 | Oral dosage form containing a PDE 4 inhibitor as an active ingredient and polyvinylpyrrolidon as excipient Dosage forms for oral administration of a PDE 4 inhibitor whose solubility is slight are described. They contain PVP as binder. ... | 05/31/2011 |
| 7947744 | Stable pharmaceutical products Provided herein is a stable pharmaceutical product comprising a dry powder inhalation device, and a pharmaceutical composition that comprises R,R-Formoterol L-tartrate salt, in particular crystalline R,R-formoterol L-tartrate; and ciclesonide. ... | 05/24/2011 |
| 7879833 | Combination medicament The invention relates to the combination of ciclesonide with formoterol. ... | 02/01/2011 |
| 7851472 | Triazolophthalazines The compounds of formula I in which R1 and R2 have the meanings as given in the description are novel effective PDE2 inhibitors. ... | 12/14/2010 |
| 7838521 | 3-oxa-10-aza-phenanthrenes The compounds of formula I in which R1, R2 and R3 have the meanings as given in the description, are novel effective PDE4 inhibitors. ... | 11/23/2010 |
| 7820669 | 2-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors. ... | 10/26/2010 |
| 7794752 | Preparation and administration form comprising an acid-labile active compound Novel administration forms and preparations for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprisi... | 09/14/2010 |
| 7790710 | Imidazopyridine derivatives useful as iNOS inhibitors The compounds of formula (I) in which R1, R11 and A have the meanings as given in the description are novel effective iNOS inhibitors. ... | 09/07/2010 |
| 7790198 | Preparation and administration form comprising an acid-labile active compound Novel administration forms and preparation for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprisin... | 09/07/2010 |
| 7785630 | Preparation and administration form comprising an acid-labile active compound Novel administration forms and preparation for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprisin... | 08/31/2010 |
| 7776893 | Use of PDE4 inhibitors for the treatment of diabetes mellitus The invention relates to the use of certain known PIDE4 inhibitors for the treatment of diabetes mellitus and accompanying disorders thereof. ... | 08/17/2010 |
| 7736673 | Stabilized pharmaceutical product The invention relates to the use of an adsorbent and a sealed package, for example an overwrap, to protect a pharmaceutical product in a solid state in the presence of a reducing sugar. ... | 06/15/2010 |
| 7718668 | Salts of 6-heterocycle substituted hexahydrophenanthridine derivatives The invention relates to salts of 6-heteroaryl substituted hexahydrophenanthridine PDE4-inhibiting compounds, which can be used in the pharmaceutical industry for the production of pharmaceutical compositions for use, e.g., in treatment of airway disorders. ... | 05/18/2010 |
| 7671050 | Triazolophthalazines The compounds of formula (I) in which R1, R2 and R3 have the meanings as given in the description are novel effective PDE2 inhibitors. ... | 03/02/2010 |
| 7666872 | Use for PDE5 inhibitors The present invention is concerned with the use of PDE5 inhibitors in medicine. ... | 02/23/2010 |
| 7641050 | Medicine pack The present invention relates to a novel type of medicine pack comprising a plurality of blister units (1), said blister units (1) each having a protective case (6), with a blister strip (4) located therein, the blister strip (4) b... | 01/05/2010 |
| 7632844 | 2-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors The compounds of formula I in which R1, R2, R3, R31, R4, R5, R6 and R7 have the meanings as indicated in the description, are novel effective PDE4 inhibitors. ... | 12/15/2009 |
| 7629361 | Salt of (S)-pantoprazole and its hydrates The invention relates to (−)-pantoprazole magnesium and its hydrates and to medicaments comprising these compounds. ... | 12/08/2009 |
| 7601737 | Isotopically substituted proton pump inhibitors The invention relates to compounds of formula 1 and formula 10 and to compositions comprising these compounds and methods of treating gastrointestinal disorders by administering t... | 10/13/2009 |
| 7585872 | Guanidinyl-substituted hydroxy-6-phenylphenanthridines as effective phosphodiesterase (PDE) 4 inhibitors The compounds of a certain formula (1), in which R1, R2, R3, R31, R4, R5, R6 and R7 have the meanings as given in the description, are novel effective PDE4 inhibitors. ... | 09/08/2009 |
| 7494990 | 2-(piperidin-4-yl)-4,5-dihydro-2H-pyridazin-3-one derivatives as PDE4 inhibitors The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors. ... | 02/24/2009 |
| 7470704 | Benzonaphthyridines The compounds of formula I in which R1, R2, R3, R4, R5, R6 and n have the meanings as indicated in the description, are novel effective PDE3/4 inhibitors. ... | 12/30/2008 |
| 7468433 | Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21-dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation The invention relates to a process for the preparation of 16,17-[(cyclohexylmethylene)bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione[11β,16α(R)] and similar compounds, by reaction of an appropriate 16,17-ketal with cyclohexanealdehyde. ... | 12/23/2008 |
| 7452998 | Process for preparing optically pure active compounds The invention relates to a novel process for preparing an optically pure PPI having a sulfinyl structure using a chiral zirconium complex or a chiral hafnium complex. ... | 11/18/2008 |
| D580547 | Tablet | 11/11/2008 |
| 7423046 | 3-hydroxy-6-phenylphenanthridines as pde-4 inhibitors Compounds of formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meaning indicated in the description, are novel effective PDE4 inhibitors. ... | 09/09/2008 |
| 7402321 | Oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles The invention relates to an oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles and their salts, which comprises the active compound together with tablet disintegrants and is provided with a film coating customary per se for sustained-release c... | 07/22/2008 |
| 7357943 | Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient The present invention relates to the field of pharmaceutical technology and describes a novel pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient, in particular an acid-labile proton pump inhibitor. The invention also r... | 04/15/2008 |
| 7351723 | Freeze-dried pantoprazole preparation and pantoprazole injection Lyophilized pantoprazole preparations which are obtainable by freeze-drying of an aqueous solution of pantoprazole, ethylenediamine tetraacetic acid and/or a suitable salt thereof, and sodium hydroxide and/or sodium carbonate are disclosed. The preparations have adv... | 04/01/2008 |
| 7329676 | 2-hydroxy-6-phenylphenanthridines as PDE-4 inhibitors The compounds of formula I in which R1, R2, R3, R31, R4, R5, R6 and R7 have the meanings as indicated in the description, are novel effective PDE4 inhibitors. ... | 02/12/2008 |
| 7279488 | Imidazopyridine-derivatives as inducible no-synthase inhibitors The compounds of Formula (I) in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors. ... | 10/09/2007 |