Bizarre Patents
User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
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| Number | Title | Issue Date |
| 8177767 | Cartridge and medical delivery system accommodating such cartridge A cartridge having a distal end provided with a mechanical coding. The coding has the form of a circular protrusion where the circular outer diameter is dedicated a specific concentration of insulin contained in the cartridge. The distal end of the cartridge is fitt... | 05/15/2012 |
| 8167841 | Transcutaneous device assembly A medical device is provided comprising a cannula having a distal portion adapted to be arranged through the skin of the subject, and an outer needle arranged coaxially with and being axially moveable relative to the cannula, the needle comprising a pointed distal e... | 05/01/2012 |
| 8158583 | Soluble pharmaceutical compositions for parenteral administration comprising a GLP-1 peptide and an insulin peptide of short time action for treatment of diabetes and bulimia Pharmaceutical composition for parenteral administration comprising a meal related insulin peptide and an insulinotropic peptide. ... | 04/17/2012 |
| 8153395 | Method of making activated carboxypeptidases The invention is related to a method for making an activated carboxypeptidase in a fungi cell comprising introducing a DNA sequence encoding a proform of the carboxypeptidase wherein a Kex2 site has been introduced in the prosequence of the carboxypeptidase, culturi... | 04/10/2012 |
| 8148412 | Heteroaromatic glucokinase activators The present invention describes 2,3-di-substituted N-heteroaromatic propionamides, of Formula (I) wherein the substitution at the 3-position is an optionally substituted phenyl ring and the substitution at the 2-position is an alkyl or cycloalkyl group; pharmaceutic... | 04/03/2012 |
| 8138185 | Urea glucokinase activators This application relates to novel urea glucokinase activators and use of the compounds of the invention for preparation of a medicament for the treatment of various diseases, e.g. for the treatment of type 2 diabetes. Further encompassed is a pharmaceutical composit... | 03/20/2012 |
| 8137325 | Needle mounting system and a method for mounting a needle assembly A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. Th... | 03/20/2012 |
| 8129343 | Acylated GLP-1 compounds Protracted GLP-1 compounds and therapeutic uses thereof. ... | 03/06/2012 |
| 8129146 | Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast Novel insulin precursors and insulin precursor analogs comprising a connecting peptide (mini C-peptide) of preferably up to 15 amino acid residues and comprising at least one Gly are provided. The precursors can be converted into human insulin or a human insulin ana... | 03/06/2012 |
| 8119775 | Human anti-KIR antibodies Compositions and methods for regulating an immune response in a subject are described. More particularly, described are human antibodies that regulate the activity of NK cells and allow a potentiation of NK cell cytotoxicity in mammalian subjects, and antibodies hav... | 02/21/2012 |
| 8118781 | Fluid infusion system, a method of assembling such system and drug reservoir for use in the system The present application relates to methods and devices for providing a reduced risk of free flow from medical devices such as an infusion pump. A medicament containing reservoir (100) is provided with a piston having a sealing portion (121) formed by a... | 02/21/2012 |
| 8114959 | Stabilized pharmaceutical peptide compositions Method for increasing the shelf-life of a pharmaceutical composition comprising a glucagon-like peptide which is prepared from a peptide product that has been dried at a pH above neutral pH. ... | 02/14/2012 |
| 8114833 | Propylene glycol-containing peptide formulations which are optimal for production and for use in injection devices The present invention relates to pharmaceutical formulations comprising a peptide and propylene glycol, to methods of preparing such formulations, and to uses of such formulations in the treatment of diseases and conditions for which use of the peptide contained in ... | 02/14/2012 |
| 8097698 | Derivatives of GLP-1 analogs The present invention relates to a pharmaceutical composition comprising a GLP-1 derivative having a lipophilic substituent; and a surfactant. ... | 01/17/2012 |
| 8097584 | Stabilized formulations of insulin that comprise ethylenediamine The present invention relates to a pharmaceutical formulation comprising insulin, an insulin analogue or an insulin derivate and ethylenediamine or salts thereof and an antimicrobial preservative agent. ... | 01/17/2012 |
| 8096978 | Automatic injection device with a top release mechanism The present invention relates to a handheld mechanical injection device by which set doses of a liquid medicament can be injected from a medical reservoir. The medicament is expelled through an injection needle by release of a power reservoir in the device, the powe... | 01/17/2012 |
| 8088900 | Two-phase precipitation of proteins Provided are new methods for precipitating proteins comprising (a) providing a protein solution, (b) adding a salt to the solution, (c) either (i) adjusting pH of the composition to below the pI of the protein (in cases where the method is directed towards precipita... | 01/03/2012 |
| 8088731 | Use of GLP-1 compound for treatment of critically ill patients Use of medicament for life saving treatment of critically ill patients and method of treatment. The medicament comprises a GLP-1 compound which effectively controls the blood glucose level. ... | 01/03/2012 |
| 8084053 | Dry mouldable drug formulation Solid pharmaceutical compositions and methods of making and administering for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the ... | 12/27/2011 |
| 8083711 | Injection device with internal dose indicator The present invention relates to an injection device comprising a housing, a resilient member adapted to provide a force in the axial direction of the injection device for ejecting a dose from the injection device. The injection device further comprises a dose setti... | 12/27/2011 |
| 8076292 | Factor VIII: remodeling and glycoconjugation of factor VIII The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide. ... | 12/13/2011 |
| 8075522 | Disposable double pointed injection needle, and an insulin injection system comprising a disposable double pointed injection needle A disposable double pointed injection needle has a needle hub to which a thin needle cannula is permanently fasten and which needle hub can be mounted on to a syringe comprising a dose setting and injection mechanism and a cartridge containing a liquid medicine to b... | 12/13/2011 |
| 8067554 | Ion exchange chromatography of GLP-1, analogs and derivatives thereof The present invention relates to an ion exchange chromatography process for purifying GLP-1 or an analog or a derivative thereof from a mixture containing said GLP-1 and related impurities, and to an industrial method including such ion exchange chromatography proce... | 11/29/2011 |
| 8063081 | Aryl carbonyl derivatives as therapeutic agents This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. ... | 11/22/2011 |
| 8063015 | Glycopegylation methods and proteins/peptides produced by the methods The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide. ... | 11/22/2011 |
| 8062253 | Medical skin mountable device A medical device is provided comprising a transcutaneous device unit and a reservoir unit. The transcutaneous device unit comprises a transcutaneous device for transporting a fluid through a skin portion of a subject, and a mounting surface adapted for application t... | 11/22/2011 |
| 8052655 | Injection device with electronic detecting means An injection device (1) for injecting a dose of drug, e.g. insulin for diabetes treatment, in which energy is stored in a spring member (9, 24) during dose setting. The stored energy is released and used for driving an injection mechanism during inject... | 11/08/2011 |
| 8049519 | Contact free absolute position determination of a moving element in a medication delivery device The present invention relates to a medication delivery device for expelling set doses of medicament, the medication delivery device comprising a position determining assembly for detecting absolute positions of a rotatably mounted member arranged within the device, ... | 11/01/2011 |
| 8043833 | Expression of soluble therapeutic proteins The present invention provides enhanced methods of producing soluble, active fibroblast growth factor-20 (FGF-20), FGF-21, neurotrophin-3 (NT-3), growth hormone (GH), granulocyte colony stimulating factor (G-CSF), or glucocerebrosidase proteins in microorganisms tha... | 10/25/2011 |
| 8040236 | Medication delivery device with reminder unit The present invention relates to a medication delivery device comprising a reminder unit for reminding an individual having a medical diseases to take a medicament. The reminder unit comprises means for providing a reminder signal to the individual having the medica... | 10/18/2011 |
| 8034326 | IL-21 variants IL-21 variant are provided wherein amino acids have been deleted and/or substituted in the region consisting of amino acid No. 65-96. ... | 10/11/2011 |
| 8030273 | Protracted exendin-4 compounds Novel protracted exendin-4 compounds and therapeutic uses thereof. ... | 10/04/2011 |
| 8013116 | Therapeutic peptides and method A polypeptide comprising one or more sequences derived from CDR2 or CDR3 of a TREM-1 protein, characterized by the ability to treat, ameliorate, or lessen the symptoms of conditions including sepsis, septic shock or sepsis-like conditions and IBD. ... | 09/06/2011 |
| 8008252 | Factor VII: remodeling and glycoconjugation of Factor VII The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide. ... | 08/30/2011 |
| 8003605 | Minimising body weight gain in insulin treatment A method for minimizing weight gain, preventing weight gain or inducing weight loss in a mammal, said method involving a treatment regimen which comprises administration of an insulin derivative having a substituent containing from 6 to 40 carbon atoms attached to o... | 08/23/2011 |
| 7999114 | Dicycloalkylcarbamoyl ureas as glucokinase activators This invention relates to dicycloalkylcarbamoyl ureas of formula (I), which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. | 08/16/2011 |
| 7981085 | Internal needle inserter A device comprises a housing having a mounting surface adapted for application to the skin of a subject, a needle with a pointed end portion adapted to penetrate the skin the subject, the needle having a first position in which the distal end portion is retracted wi... | 07/19/2011 |
| 7972558 | Method and an apparatus for sterilizing packaging material A method and an apparatus for sterilizing packaging material for use in packaging for protein containing products, such as food products or medical drugs. The packaging material is sterilized by irradiating it using a beam of ionizing radiation, such as an electron ... | 07/05/2011 |
| 7956032 | Glycopegylated granulocyte colony stimulating factor The present invention provides conjugates between Granulocyte Colony Stimulating Factor and PEG moieties. The conjugates are linked via an intact glycosyl linking group that is interposed between and covalently attached to the peptide and the modifying group. The co... | 06/07/2011 |
| 7955297 | Retraction means for transcutaneous device The invention provides a transcutaneous medical device (502, 250, 150, 600) comprising a lower surface adapted for application towards the skin of a subject, attaching means (571, 272, 161) for securing the lower surface relative to the skin, and a tra... | 06/07/2011 |
