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Assignee: Novo Industri A/S (DK)


Location: Not specified.
No. of patents: 49

1    
NumberTitleIssue Date
4816441Peptides and compositions
Peptides of the formula R1 -His-Asp-Glu-Ala-R wherein R1 is Ala-Gln, and R is a polypeptide residue with up to 50 amino acid residues, and wherein one, more or all of the amino acid residues in R1 and/or R independently ma...
03/28/1989
4675191Method for production of a low alcoholic wine
Generating a low alcohol content wine by oxidizing the glucose content in unfermented grape juice to gluconic acid through treatment of the juice with glucose oxidase in the presence of oxygen followed by fermentation. The process may be carried out to adjust ...
06/23/1987
4665028Method for production of an immobilized enzyme preparation by means of a crosslinking agent
A method for production of an immobilized enzyme by means of a crosslinking agent wherein the following components are brought together in aqueous medium: (a) an enzyme preparation; (b) a crosslinking agent; and (c) an inert water soluble salt in a relatively ...
05/12/1987
4661452Enzyme containing granulates useful as detergent additives
Enzyme containing granulates containing less than 2% chloride and besides enzyme, coating materials, granulating aids and water, more than 35% w/w of a filler system consisting of from 5-70% w/w of the granulate composition of one or more water soluble su...
04/28/1987
4617273Alpha-acetolactate decarboxylase enzyme and preparation thereof
A novel alpha-acetolactate decarboxylase enzyme product with improved stability is provided. The novel enzyme is produced in high levels by cultivation of Bacillus strains selected from the group consisting of Bacillus brevis and Bacillus licheniformis AT...
10/14/1986
4614730Stabilized insulin preparations and a process for preparation thereof
Isulin solutions physically stabilized by presence of one or more phospholipids, preferably a lecithin. The phospholipid is present in concentration of 10-200 μg/ml....
09/30/1986
4604355Maltogenic amylase enzyme, preparation and use thereof
A novel maltogenic amylase enzyme with improved thermostability is provided. The novel enzyme can be produced by cultivating a newly discovered microorganism Bacillus strain NCIB 11837 belonging to the Bacillus stearothermophilus complex....
08/05/1986
4598065Use of peptides as medicaments and certain novel peptides
Certain peptides containing the glucagon1-21 peptide chain His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Al a-Gln-Asp, usable as a medicament or a diagnostic; the peptide exerts a spasmolytic effect and an inhibitory ef...
07/01/1986
4598048Preparation of a maltogenic amylase enzyme
A maltogenic amylase enzyme with improved thermostability, which can be produced by cultivating Bacillus strain NCIB 11837 belonging to the Bacillus stearothermophilus complex, is made by cultivation of a host microorganism transformed with the gene codin...
07/01/1986
4592745Dispenser
An dispenser characterized by provision for use of a replaceable needle and a prefilled cartridge. The dispenser comprises an elongated body separable into two body sections, with the front end section adapted to contain a prefilled cartridge and with pro...
06/03/1986
4591565Method for thermal destabilization of microbial rennet
Thermal stability of microbial rennet is reduced by treatment of the rennet in aqueous medium with aliphatic or inorganic peroxy acids or salts thereof. Preferably, the microbial rennet is Mucor Miehei rennet and the peroxy acid is a lower aliphatic perox...
05/27/1986
4572897Carrier for immobilizing enzymes
Immobilized enzyme granules prepared by mixing inert filler particles into an aqueous solution or dispersion of a water soluble binder, followed by granulating the mixture so as to form carrier granules. Enzyme is immobilized on the hydrophilic surfaces o...
02/25/1986
4560651Debranching enzyme product, preparation and use thereof
A novel debranching enzyme product with properties in terms of thermostability and pH-optimum comparable to those of glucoamylase is produced by cultivating a strain belonging to the novel taxonomic group Bacillus acidopullulyticus. The novel debranching ...
12/24/1985
4543333Liquid proteinase concentrate and method for preparation
A storage stable liquid enzyme concentrate of Subtilisin Carlsberg containing 0.5-6.5 Anson Units of proteinase per gram of concentrate and method for preparing same. Solid form proteinase is extracted with 70-100 parts by volume propylene glycol, 30-0 pa...
09/24/1985
4519934Liquid enzyme concentrates containing alpha-amylase
A liquid enzyme concentrate containing the alpha-amylase from Bacillus licheniformis and optionally a proteinase dissolved in 40-95% by weight propylene glycol 1,2 balance water, at pH 5-9, the enzyme activity being 10-1000 KNU/g of concentrate. Proteinas...
05/28/1985
4497897Liquid proteinase concentrate and method for preparation
A storage stable liquid enzyme concentrate of Subtilisin Carlsberg containing 0.5-6.5 Anson Units of proteinase per gram of concentrate and method for preparing same. Solid form proteinase is extracted with 70-100 parts by volume propylene glycol, 30-0 pa...
02/05/1985
4489159Process for preparing esters of human insulin
A process for converting human des-B30-insulin, namely ##STR1## into h-In-ThrB30 esters through amidation with an L-threonine ester in a mixture of water and a water miscible solvent in the presence of trypsin and optionally an acid. Yield...
12/18/1984
4483876Enzymatic method for production of instant tea
Enzymatic method for production of instant tea, comprising treating tea leaves with an SPS-ase preparation, whereby the extract yield is improved, and instant tea made with the extract exhibits superior clarity....
11/20/1984
4483875Enzymatic treatment of pomace
Treatment of pomace or comminuted suspension of whole fruits and vegetables with SPS-ase alone or combined with cellulase to increase juice yield and improve separation of residual pomace solids from juice product....
11/20/1984
4483874Preparation of milk substitute
Preparation of a proteinaceous material suited for use in milk substitutes by treatment of crude vegetable proteins such as soy flour, faba bean flour and the like with an SPS-ase preparation. In addition to conversion of the vegetable protein, the treatm...
11/20/1984
4478940Production of purified vegetable protein
Purified vegetable protein particularly from soymeal produced by enzymatic treatment to dissolve the remanence employing a novel enzyme composition agent adapted to decompose a hitherto unreported pectic-like polysaccharide capable of binding to proteins....
10/23/1984
4478939SPS, SPS-ase and method for producing SPS-ase
SPS--A novel pectic-like polysaccharide derived from soy plant cell walls characterized by capability to bind to proteins. SPS-ase--The carbohydrase complex capable of decomposing SPS into decomposition products incapable of attaching to protein, and method fo...
10/23/1984
4478856Production of purified vegetable protein
A process for recovering purified vegetable protein particularly soymeal protein by enzymatic treatment to dissolve the remanence employing a novel enzyme composition agent adapted to decompose a hitherto unreported pectic-like polysaccharide capable of b...
10/23/1984
4478854Method of treating plant polysaccharides
Hydrolysis of plant kingdom polysaccharides by treatment with SPS-ase preparations. SPS-ase is an enzyme adapted to hydrolyzing the water-soluble protein binding polysaccharide present in soy flour decomposed by use of conventional pectinases, which polys...
10/23/1984
4476118Stabilized insulin preparations
Novel pharmaceutical solutions of dissolved insulin having improved physical stability prepared by incorporating therein an essentially ionized zinc salt in a concentration corresponding to a content of zinc ions at the disposal of the insulin of more tha...
10/09/1984
4472385Stabilized insulin preparations and method for their production
Novel pharmaceutical preparations of dissolved insulin having improved physical stability particularly adapted for use in continuous insulin delivery equipment prepared by incorporating therein a calcium or magnesium salt so as to provide a solution conta...
09/18/1984
4462980Stabilized plasmin compositions and method for preparation thereof
Novel plasmin compositions, conditioned for labelling with technetium-99m by containing a pertechnetate reducing reagent, and plasmin admixed with a plasmin stabilizing agent. The novel compositions are particularly suited for the preparation of technetiu...
07/31/1984
4455375Stabilized rennet solution
A stabilized solution of rennet; the stabilizing agent being methionine. The stabilizing agent is added in an amount corresponding to a concentration of between 0.1% (w/w) and saturation calculated on the total weight of the solution....
06/19/1984
4439455Enzymatic treatment of wine and must
The filterability of wine and must obtained from grapes infected with the mold Botrytis cinerea is improved by treatment thereof with an enzyme product produced by cultivating the microorganism Trichoderma harzianum. The enzyme product exhibits both alpha...
03/27/1984
4435307Detergent cellulase
A harshness reducing, enzymatic additive for a main wash detergent based on a fungal cellulase, i.e., a cellulase produced by means of Humicola insolens. The enzymatic additive can be produced in high yields and has an extraordinarily high activity at alk...
03/06/1984
4431629Method of producing an egg white substitute material
Method of producing an egg white substitute material from soy protein. The method comprises extraction of a defatted soy bean material at a pH between about 6.0 and 10.5, separation, subjection of the supernatant to one or more ultrafiltrations and proteo...
02/14/1984
4405608Novel peptide
A novel, purified peptide having the following amino acid sequence: Arg-Ser-Leu-Gln-Asn-Thr-Glu-Glu-Lys-Ser-Arg-Ser-Phe-Pro-Ala-Pro-Gln-Thr-Asp -Pro-Leu-Asp-Asp-Pro-Asp-Gln-Met-Thr-Glu-Asp. The peptide may be used as medicament, e.g., in the treatment of gastro...
09/20/1983
4386160Thermal destabilization of bacillus serine proteases
Bacillus serine proteases are acylated with an acyl radical of a monocarboxylic or dicarboxylic acid of about 1 to 6 carbon atoms to thermally destabilize the proteases at least about 3° C. The acylated proteases have at least about 50% of their activity...
05/31/1983
4371552Prune juice production using cellulase
The disintegration process for prune juice production is improved through cooking prunes until substantial disintegration has taken place followed by treatment with cellulase, e.g., the cellulase of Trichoderma reesei, and optionally with a pectinase, whi...
02/01/1983
4370317Pancreatic spasmolytic polypeptide
The invention relates to a novel purified polypeptide which is recoverable from porcine pancreas glands. The amino acid composition of the said polypeptide has been determined to be as follows: Trp (2), Lys (4), His (1), Arg (5), Asx (10), Thr (3), Ser (9), Gl...
01/25/1983
4357357Thermal destabilization of microbial rennet
Microbial rennet such as from Mucor miehei is thermally destabilized by treatment of the rennet in an aqueous medium with oxidizing agents containing active chlorine such as hypochlorites. The thermally destabilized rennet is advantageous for cheese makin...
11/02/1982
4343898Process for preparing esters of human insulin
A process for converting insulin compounds containing the human insulin moiety ##STR1## into h-In-ThrB30 esters through transpeptidation of such insulin compounds with a threonine ester in solution of water and a water miscible solven...
08/10/1982
4335208Saccharification of starch hydrolysates
Saccharifying starch hydrolysate to a high DX glucose syrup at pH 3-5 by the enzyme mixture of a glucoamylase and an acidophilic iso-amylase. A lower dosage level than the heretofore conventional glucoamylase dosage may be employed and higher DX glucose s...
06/15/1982
4324805Method of producing soy protein hydrolysate from fat-containing soy material, and soy protein hydrolysate
A method for producing soy protein hydrolysate involving water washing fat-containing soy material at a pH of 3.5-5.5 thereby partially defatting the soy material; then hydrolyzing the partially defatted soy material with a proteolytic enzyme in the prese...
04/13/1982
4316956Fermentation process
This invention relates to a novel fermentation process and in particular, to fermentative production of ethanol producing in the presence of non-gelled, or granular, starch particles, alpha-amylase and a glucoamylase; characteristic of the present process...
02/23/1982
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