Did You Know...
...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."
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| Number | Title | Issue Date |
| 7851634 | 5-amino 4-hydroxy-7-(1H-indolmethyl)-8-methylnonamide derivatives as renin inhibitors for the treatment of hypertension The application relates to novel alkanamides of the general formula (I) where X is —CH2— or >CH—OH; (A) R1 is e.g. an optionally substituted heterocyclyl radical or an optionally substituted polycyclic, unsaturated hydrocarbon radical whe... | 12/14/2010 |
| 7851475 | Substituted pyrrole-2, 5-diones as protein kinase C inhibitors A compound of formula I wherein R, Ra and Rb are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containin... | 12/14/2010 |
| 7851439 | EFTU inhibitors or aminothiazoles and their uses Organic compounds that are useful for the treatment, prevention and/or amelioration of diseases are described. ... | 12/14/2010 |
| 7842296 | Sequences from The present invention relates to a fish vaccine. More specifically the invention relates to a vaccine to protect salmon against infection by Piscirickettsia salmonis. The invention is based on or derived from the nucleic acid or amino acid sequence of antigen... | 11/30/2010 |
| 7838674 | Tetracyclic lactame derivatives The present invention describes tetracyclic compounds of formula (IA) or (IB), wherein the symbols R, X, A, Y, R2, R3 and D are as defined in the specification, their use in the treatment of certain diseases, e.g. depending... | 11/23/2010 |
| 7837323 | Colored contact lens with a more natural appearance A colored contact lens having a non-opaque pupil section, an iris section surrounding the pupil section, and a colored, opaque intermittent pattern made up of a plurality of elements located over the entire iris section that leaves a substantial portion within the i... | 11/23/2010 |
| 7834144 | Prion-specific peptoid reagents The invention relates to peptoid reagents that interact preferentially with a pathogenic form of a conformational disease protein as compared to a nonpathogenic form of the conformational disease protein where the peptoid reagent comprises an amino-terminal region, ... | 11/16/2010 |
| 7833803 | Analysis of liquid chromatography eluates When analysing saccharides by HPAEC, the eluate from the column is typically analysed using a amperometric detector. According to the invention, amperometric detection is coupled with ultraviolet detection, with both methods being applied to the eluate. Thus the inv... | 11/16/2010 |
| 7828441 | Generalized presbyopic correction methodology An adaptive optics phoropter is aligned with a Badal optometer and an adjustable aperture component to subjectively determine an optimal vision correction as a power profile for an ophthalmic lens or ablating a cornea. The optimal power profile is preferably determi... | 11/09/2010 |
| 7825260 | Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators Compounds of formula I, wherein X, a, b, R1, R2, R3, R4 and R5 are as defined in the specification, processes for their production, their uses and pharmaceutical compos... | 11/02/2010 |
| 7825247 | N-phenyl-2-pyrimidine-amine derivatives The present invention relates to novel amides and a process for preparing these amides. ... | 11/02/2010 |
| 7825222 | Therapeutic binding molecules A molecule comprising at least one antigen binding site, comprising in sequence the hypervariable regions CDR1, CDR2 and CDR3, said CDR1 having the amino acid sequence Asn-Tyr-Ile-Ile-His (NYIIH), said CDR2 having the amino acid sequence Tyr-Phe-Asn-Pro-Tyr-Asn-His-... | 11/02/2010 |
| 7825152 | Organic compounds and their uses The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases. ... | 11/02/2010 |
| 7825141 | Epothilone derivatives Epothilone derivatives of Formula (I) and their use as a pharmaceutical. ... | 11/02/2010 |
| D626326 | Pill container and lid combination | 11/02/2010 |
| 7820818 | Heteroaryl nitrile derivatives The invention provides compounds of formula I or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatme... | 10/26/2010 |
| 7820694 | Beta-2-adrenoreceptor agonists Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3 | 10/26/2010 |
| 7820672 | Indolylmaleimide derivatives The compounds are indolylmaleimide derivatives comprising either a substituted pyridyl or indolyl residue. The compounds have interesting pharmaceutical properties, e.g. in the treatment and/or prevention of T-cell mediated acute or chronic inflammatory diseases or ... | 10/26/2010 |
| 7820106 | Sensor platform, apparatus incorporating the platform and process using the platform A sensor platform for use in sample analysis comprises a substrate (30) of refractive index (n1) and a thin, optically transparent layer (32) of refractive index (n2) on the substrate, (n2) is greater than (n1 | 10/26/2010 |
| D625911 | Combined pill container and reversible lid | 10/26/2010 |
| 7816359 | N-phenyl-2-pyrimidine-amine derivatives The present invention relates to novel amides and a process for preparing these amides. ... | 10/19/2010 |
| 7814905 | Systems devices and methods for opening receptacles having a powder to be fluidized A method for forming at least one opening in a receptacle comprises the steps of providing a receptacle having a cover with an exterior surface and an interior surface covering a cavity. A cutting mechanism is also provided having at least one blade. The cover is pi... | 10/19/2010 |
| 7811767 | Methods and compositions for assessing acute rejection The invention relates to the analysis and identification of genes that are up-regulated simultaneously in transplant rejection. This simultaneous up-regulation of genes provides a molecular signature to accurately detect transplant rejection. ... | 10/12/2010 |
| 7807709 | Organic compounds The invention relates to the use of (3,4-di-, 3,3,4-tri, 3,4,4-tri- or 3,3,4,4-tetra-)substituted pyrrolidine compounds for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of tha... | 10/05/2010 |
| 7807438 | Preparation of purified exosomes comprising HCV RNA The invention relates to a method for isolation of hepatitis C virus. The method comprises the separation of particles termed exosomes from the blood plasma of an individual infected with hepatitis C virus (HCV) and the extraction or RNA from these exosome particles... | 10/05/2010 |
| 7807155 | IL-17 antagonistic antibodies An IL-17 binding molecule, in particular an antibody to human IL-17, more preferably a human antibody to human IL-17 is provided, wherein the hypervariable regions of the heavy and light chains have amino acid sequences as defined, for use in the treatment of an IL-... | 10/05/2010 |
| 7803924 | HSP60 from arthrobacter The hsp60 gene from a strain of Arthrobacter has been isolated and sequenced. The encoded protein is believed to be highly immunogenic, especially in fish, and also has utility as a non-specific adjuvant, and as an adjuvanting carrier for heterologous antigen... | 09/28/2010 |
| 7803804 | Substituted pyrazines for use in the treatment of inflammatory or allergic conditions Disclosed herein are substituted pyrazine compounds and tautomers, stereoisomers, solvates, or pharmaceutically acceptable salts thereof for the treatment of conditions mediated by the blockade of an epithelial sodium channel, particularly an inflammatory or allergi... | 09/28/2010 |
| 7803527 | Inactivated bovine herpes virus-1 and methods This invention related to a method of immunizing cattle to reduce the effects of infection by bovine herpes virus 1, including abortion and stillbirth, by administering inactivated bovine herpes virus 1 prior to breeding. ... | 09/28/2010 |
| 7799812 | Reverse isoxazoles The present invention relates to polycyclic compounds, processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them. ... | 09/21/2010 |
| 7799810 | Organic compounds The present invention concerns a compound of formula (I), or a pharmaceutically acceptable salt, or solvate thereof, wherein the groups Ri- Rs are defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibi... | 09/21/2010 |
| 7799780 | Condensed imidazole derivatives as aldosterone synthase inhibitors The application relates to novel heterocyclic compounds of the general formula (I) and salts, preferably pharmaceutically acceptable salts, thereof, in which R, R1, R2, R3, Q, m and n have the meanings explained in detail in the desc... | 09/21/2010 |
| 7799779 | Substituted piperidines as renin inhibitors Compounds of the general formula (I) in which the meanings of the substituents R1, R2, R3, R4, X, Z and n as stated in claim 1 have renin-inhibiting properties and can be used as medicines. ... | 09/21/2010 |
| 7798639 | Method for applying lubricious coating to a polymeric article The present invention provides a medical device, preferably an ophthalmic device, more preferably a contact lens, which comprises a lubricious coating including a capping layer of polyvinylpyrrolidone and/or at least one layer of a lubricious coating material and on... | 09/21/2010 |
| 7795387 | Rod-derived cone viability factor (RDCVF) and a method of enhancing cone cell survival by RDCVF Disclosed are methods and compositions for early diagnosis, monitoring and treatment of retinal dystrophy, age-related macular degeneration, Bardet-Biedel syndrome, Bassen-kornzweig syndrome, best disease, chroidema, gyrate atrophy, congenital amourosis, refsun synd... | 09/14/2010 |
| 7795359 | Continuous process for production of polymeric materials The invention provides a continuous-flow process for producing a polymeric material. The process of the invention comprises the steps of: introducing at least two solutions, each comprising one or more reactants, into a microreactor to mix the two solutions to form ... | 09/14/2010 |
| 7795288 | Thiazole and pyrazole derivatives as Flt-3 kinase inhibitors The invention relates to thiazole and pyrazole derivatives of formula (I) wherein Q is S and X is C, or Q is CH and X is N; R1 is unsubstituted or substituted phenyl; and R2 is unsubstituted or substituted aryl or heteroaryl; or a salt of the s... | 09/14/2010 |
| 7795273 | Pyrazolo[1,5-a]pyridine-3-carboxylic acids as EphB and VEGFR2 kinase inhibitors The invention relates to novel pyrazolo[1,5-a]pyridine-3-carboxylic acid compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to the... | 09/14/2010 |
| 7795257 | Organic compounds The present invention provides compounds of the formula which are activators of glucokinase activity and, thus, may be employed as therapeutic agents for the treatment of glucokinase mediated conditions. Accordingly, the co... | 09/14/2010 |
| 7795253 | Condensed imidazole derivatives as aromatase inhibitors The application relates to novel heterocyclic compounds of the general formula (I) and salts, preferably pharmaceutically acceptable salts, thereof, in which R, R1, R2, R3, Q, m and n have the meanings explained in detail in the desc... | 09/14/2010 |
