Did You Know...
...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."
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| Number | Title | Issue Date |
| 6001807 | Use of CRF-antagonists for treating emesis CRF-antagonists are useful in the treatment of emesis.... | 12/14/1999 |
| 5997140 | Actively controllable multifocal lens The invention provides a crosslinkable or polymerizable optical material that is suitable for producing a biocompatible holographic optical element. The optical material is a rapidly crosslinking or polymerizing material that changes from a fluid state to... | 12/07/1999 |
| 5994133 | Cell growth substrate polymer Cell growth substrate polymers are described which comprise a macromonomer of the formula (I): Q-(PFPE-L)n-1 -PFPE-Q, wherein n is at least 1.0; each PFPE may be the same or different and is a perfluorinated polyether of the formula (II): --OCH... | 11/30/1999 |
| 5994629 | Positive selection A method of selecting genetically transformed cells from a population of cells comprising introducing a desired nucleotide sequence and a co-introduced nucleotide sequence into the genome of a cell whereby the desired nucleotide sequence or the co-introdu... | 11/30/1999 |
| 5990289 | Method for the purification of proteins The instant invention relate to a new method for the purification of proteins using copper chelate-affinity chromatography, wherein the impure or pre-purified protein is adsorbed on immobilized copper(II) ions, optionally washed with buffer and deionized ... | 11/23/1999 |
| 5990116 | Trisubstituted phenyl derivatives The invention concerns compounds of formula I ##STR1## wherein the substituents have various meanings, and their use in the prevention or treatment of inflammatory and proliferative skin diseases and cancer.... | 11/23/1999 |
| 5990395 | Inbred sweet corn line W1498A An inbred sweet corn line, designated W1498A, the plants and seeds of inbred sweet corn line W1498A, methods for producing a maize plant produced by crossing the inbred sweet corn line W1498A with itself or with another maize plant, and hybrid maize seeds... | 11/23/1999 |
| 5985866 | Use of serotonin antagonists for treating fibromyalgia 5-HT3 antagonists are useful in the treatment of fibromyalgia.... | 11/16/1999 |
| 5986082 | Altered forms of the NIM1 gene conferring disease resistance in plants The NIM1 gene product is a structural homologue of the mammalian signal transduction factor I.kappa.B subclass . The present invention exploits this discovery to provide altered forms of NIM1 that act as dominant-negative regulators of the systemic... | 11/16/1999 |
| 5985906 | Antifungal composition Use of a combination of the squalene epoxidase inhibitor terbinafine and an azole 14-alpha-methyldemethylase inhibitor (fluconazole or itraconazole) in mycotic infections caused by azole-resistant fungal strains, and corresponding pharmaceutical compositi... | 11/16/1999 |
| 5985890 | Rapamycin derivatives Rapamycin derivatives selected among 32(S)-dihydro-rapamycin derivatives and 32-deoxo-rapamycin compounds. Rapamycin derivatives are disclosed of the formula: ##STR1## wherein the variables are in the specification.... | 11/16/1999 |
| 5981533 | Pyrazole derivatives and processes for the preparation thereof 4-Amino-1H-pyrazolo[3,4-d]pyrimidine derivatives of formula I ##STR1## wherein the symbols are as defined in claim 1, and intermediates for their manufacture are described. The compounds of formula I inhibit especially the tyrosine kinase activity of... | 11/09/1999 |
| 5981479 | Cyclosporins It has been found that nonimmunosuppressive, cyclophilin-binding cyclosporins are useful in the treatment and prevention of AIDS and AIDS-related disorders. Such cyclosporins include novel Ciclosporin derivatives modified at the 4- and/or 5-positions.... | 11/09/1999 |
| 5981205 | Nuclear Dbf2- related (Ndr) kinases The current invention describes the identification of a novel widely-expressed human and D. melanogaster serine/threonine protein kinase (designated nuclear, Dbf2-related kinase, or Ndr; previously referred to as Ndr) and the use of this kinase for the id... | 11/09/1999 |
| 5977066 | Cyclosporin galenic forms Pharmaceutical compositions comprising a cyclosporin as active ingredient, a fatty acid triglyceride, a glycerol fatty acid partial ester or propylene glycol or sorbitol complete or partial ester, preferably, and a tenside having an HLB of at least 10.... | 11/02/1999 |
| 5977290 | Basic catalysts for the aldol reaction The invention relates to a process for the condensation of aldehydes or ketones with C--H acidic compounds (in particular Knoevenagel reaction) in the presence of at least one molecular sieve in the form of a zeolite or sheet silicate and one alkali carbo... | 11/02/1999 |
| 5977075 | N-aroylamino acid amides as endothelin inhibitors The present invention relates to the compounds of formula (I) ##STR1## wherein R is carboxy, esterified carboxy, carbamoyl, N-(alkyl or aryl)-carbamoyl, cyano, 5-tetrazolyl or CONH--SO2 --R4 ; R1 is hydrogen, lower al... | 11/02/1999 |
| 5972934 | Stabilized nithiazine compositions Stabilized compositions of nithiazine which are suitable for long term use in an agricultural application. The compositions typically contain nithiazine, a hydroxyalkyl-tert-amine and an antioxidant. Suitable hydroxyalkyl-tert-amines include, for example,... | 10/26/1999 |
| 5973089 | Polymerizable perfluoroalkylether macromer Macromonomers of the formula I are described: Q-B(L-B)n T (I) wherein n is at least 1.0; Q is a polymerizable group; B may be the same or different and is a difunctional block of molecular weight in the range of ... | 10/26/1999 |
| 5969145 | Process for the production of epothilones and intermediate products within the process The invention relates to a process for the production of epothilones and intermediate products within the process. Epothilones A and B are natural substances, which can be produced by microorganisms, and the taxols have similar properties and are thus of ... | 10/19/1999 |
| 5965237 | Microstructure device An improved microstructure for micro-scale fluid handling, processing and investigation comprises a support element and a microstructured element. The support element has a substantially even support face. The microstructured element has a microstructured... | 10/12/1999 |
| 5962741 | Process for the production of aromatic halogen-amino compounds The present invention relates to a hydrogenation process for the production of aromatic halogen-amino compounds by means of catalytic hydrogenation on noble metal catalysts of corresponding aromatic halonitro compounds, characterised in that a rhodium, ru... | 10/05/1999 |
| 5962611 | Perfluoroalkylether macromer having two polymerizable groups A macromer of formula (I) is described: Q-(PFPE-L)n-1 -PFPE-Q, wherein n>1.0; PFPE may be the same or different and is a perfluorinated polyether of formula (II): --OCH2 CF2 O(CF2 CF2 O)x (... | 10/05/1999 |
| 5962017 | Pharmaceutical compositions comprising cyclosporins Pharmaceutical compositions comprising a cyclosporin, e.g. Ciclosporin or Nva!2 -Ciclosporin, in "microemulsion pre-concentrate" and microemulsion form. The compositions typically comprise (1.1) a C1-5 alkyl or tetrahydrofurfuryl d... | 10/05/1999 |
| 5962014 | Pharmaceutical compositions comprising cyclosporins Pharmaceutical compositions comprising a cyclosporin, e.g. Ciclosporin or Nva!2 -Ciclosporin, in "microemulsion pre-concentrate" and microemulsion form. The compositions typically comprise (1.1) a C1-5 alkyl or tetrahydrofurfuryl d... | 10/05/1999 |
| 5958876 | Cyclosporin-containing pharmaceutical compositions The present invention relates to a cyclosporin-containing soft capsule preparation which contains a composition containing cyclosporin as an active ingredient; a non-hydrophilic component propylene carbonate or a mixture of propylene carbonate and a hydro... | 09/28/1999 |
| 5955348 | Genetically modified pseudomonas strains with enhanced biocontrol activity Strains of Pseudomonas have been genetically engineered to have enhanced biocontrol properties. The strains of the invention are particularly effective against plant pathogenic fungi such as species of Rhizoctonia and Pythium, because the strains produce ... | 09/21/1999 |
| 5951971 | Ophthalmic compositions An ophthalmic composition particularly in the form of eye-drops suitable for the treatment of diseases of the eye and surrounding areas. The composition contains a cyclosporin and a surfactant selected from polyoxyethylene fatty acid esters, polyoxyethyle... | 09/14/1999 |
| 5948904 | Process for the preparation of aromatic carbamoyl-substituted polysaccharide derivatives The invention relates to a process for the preparation of polysaccharide-N-arylcarbamates in suitable form as supports for chromatography, which process comprises adding to polysaccharide carbamates, which may be substituted in the aryl moiety, an N-... | 09/07/1999 |
| 5945498 | Polysiloxane-comprising perfluoroalkyl ethers and the preparation and use thereof The present invention describes a free radical polymerizable segmented macromonomer based on perfluoroelkyl ether, polysiloxane and divalent organic segments. This macromoner can be polymerized and used to form moldings, contact lenses, corneal implants a... | 08/31/1999 |
| 5945584 | Soybean cultivar S59-V6 The invention is a novel soybean cultivar designated S59-V6 with high yield potential and tolerance to Roundup herbicide. The invention relates to seeds of the cultivar S59-V6, plants of the cultivar S59-V6, and to methods for producing a soybean plant pr... | 08/31/1999 |
| 5939466 | Poly-unsaturated carbohydrate derivatives, polymers thereof and their use The present invention relates to polymerizable derivatives of carbohydrates comprising a carbohydrate radical and more than one radically polymerizable hydrocarbon group which is linked optionally via a spacer to the carbohydrate radical, to homopolymers,... | 08/17/1999 |
| 5939604 | Soybean cultivar S14-M7 The invention is a novel soybean cultivar designated S14-M7 with high yield potential and tolerance to Roundup herbicide. The invention relates to seeds of the cultivar S14-M7, plants of the cultivar S14-M7, and to methods for producing a soybean plant pr... | 08/17/1999 |
| 5939489 | Crosslinked polymers containing salt structures The invention relates to a process for the production of moldings, in particular contact lenses, in which a water-soluble crosslinkable polymer is crosslinked in solution, and to moldings, in particular contact lenses, obtainable by this process. The pres... | 08/17/1999 |
| 5935998 | Use of all allylamine derivatives such as terbinafine, in the manufacture of a medicament for the treatment of helicobacter pylori infection or associated diseases Use of compounds of formula (I), wherein R has various significances, in free base form or in pharmaceutically acceptable salt form, as agents against H. pylori infection and associated diseases.... | 08/10/1999 |
| 5932674 | Crosslinked polymers The invention relates to a novel process for the production of mouldings, in particular contact lenses, in which a soluble prepolymer comprising units containing a crosslinkable group and at least one unit containing a modifier is crosslinked in solution,... | 08/03/1999 |
| 5932243 | Galenical formulations A pharmaceutical composition containing macrolide, e.g. a rapamycin compound in an emulsion preconcentrate or microemulsion preconcentrate for oral administration. The carrier medium for the rapamycin compound includes a hydrophilic phase, a lipophilic ph... | 08/03/1999 |
| 5929067 | 1-aryl-2-acylamino-ethane compounds and their use as neurokinin especially neurokinin 1 antagonists 1-Aryl-2-acylaminoethane compounds of formula I ##STR1## wherein R1 -R4, X and Am are as defined in the description, have valuable pharmaceutical properties and are especially effective as NK-1 antagonists.... | 07/27/1999 |
| 5925778 | Dihalogenated ferrocenes and processes for the preparation thereof The invention relates to a compound of formula (I), wherein R1 is C1 -C8 alkyl, phenyl or phenyl substituted by from 1 to 3 C1 -C4 alkyl or C1 -C4 alkoxy substituents; R2 ... | 07/20/1999 |
| 5925811 | Soybean cultivar S28-V8 The invention is a novel soybean cultivar designated S28-V8 with high yield potential and tolerance to Roundup herbicide. The invention relates to seeds of the cultivar S28-V8, plants of the cultivar S28-V8, and to methods for producing a soybean plant pr... | 07/20/1999 |
