Bizarre Patents
Method and apparatus for making a drink hop along a bar or counter
A method for generating a drink which appears to hop from a remote spot on the bar or counter and take one or more leaps, before landing in a patron's glass.
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| Number | Title | Issue Date |
| 8119612 | RNAi inhibition of alpha-ENaC expression The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides. ... | 02/21/2012 |
| 8119131 | IL-17 antagonistic antibodies An IL-17 binding molecule, in particular an antibody to human IL-17, more preferably a human antibody to human IL-17 is provided, wherein the hypervariable regions of the heavy and light chains have amino acid sequences as defined, for use in the treatment of an IL-... | 02/21/2012 |
| 8115917 | Drying nozzle A drying nozzle (1) for drying a peripheral portion of an ophthalmic lens (CL), in particular a contact lens, comprises an inlet (30) for the supply of a pressurized gas and a continuous annular outlet gap (11) having a predetermined width (W) t... | 02/14/2012 |
| 8115016 | Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP... | 02/14/2012 |
| 8115009 | UV-absorbers for ophthalmic lens materials 1,4-disubstituted-1,2,3-triazole UV absorbing monomers are disclosed. The UV absorbers are particularly suitable for use in intraocular lens materials. ... | 02/14/2012 |
| 8114960 | Heterologous expression of Neisserial proteins Alternative and improved approaches to the heterologous expression of the proteins of Neisseria meningitidis and Neisseria gonorrhoeae. These approaches typically affect the level of expression, the ease of purification, the cellular localization, and/... | 02/14/2012 |
| 8114877 | Organic compounds Compounds of formula I in free or salt form, wherein R1, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by activation of the adeno... | 02/14/2012 |
| 8114849 | Retinal dystrophy-associated protein and uses thereof Disclosed are methods and compositions for early diagnosis, monitoring and treatment of retinal dystrophy, age-related macular degeneration, Bardet-Biedel syndrome, Bassen-kornzweig syndrome, best disease, choroidema, gyrate atrophy, congenital amourosis, refsun syn... | 02/14/2012 |
| 8110224 | Pharmaceutical microparticles Microparticles consisting of (a) a matrix with a mixture of (a1) at least one hydrophobic, biologically degradable polymer and (a2) optionally at least one water-soluble polymer, (b) a pharmaceutical active ingredient distributed in the matrix, and (c) in addition a... | 02/07/2012 |
| 8106163 | Compositions and methods of use for therapeutic antibodies The present invention relates to antibodies that specifically bind to the BAFF receptor (BAFFR). The invention more specifically relates to specific antibodies that are BAFFR antagonists with in vivo B cell depleting activity and compositions and methods of use for ... | 01/31/2012 |
| 8106162 | Artificial antibody polypeptides A fibronectin type III (Fn3) polypeptide monobody, a nucleic acid molecule encoding said monobody, and a variegated nucleic acid library encoding said monobody, are provided by the invention. Also provided are methods of preparing a Fn3 polypeptide monobody, and kit... | 01/31/2012 |
| 8106081 | Combination of organic compounds useful for treating diabetes The present invention relates to a combination, especially a pharmaceutical composition, comprising as active ingredients (i) an AT1-receptor antagonist or a pharmaceutically acceptable salt thereof; (ii) (a) an insulin secretion... | 01/31/2012 |
| 8105587 | Methods of treating arthritis using IL-1β binding molecules This invention relates to methods employing IL-1β-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1beta Compounds”); such as small molecular compounds disrupting IL-1β ligand-IL-1 receptor interaction, IL-1β antibodies or IL-1 receptor an... | 01/31/2012 |
| 8105405 | Quick release filter assembly for pneumatic surgical machine A quick release filter assembly for a pneumatic module of a surgical machine includes a housing, an input port, an output port, a filter, and a flange. The housing has first and second sides, a top, and a bottom. The input port is located on the first side of the ho... | 01/31/2012 |
| 8105378 | Ophthalmic and otorhinolaryngological device materials containing an alkyl ethoxylate Disclosed are soft, high refractive index, acrylic device materials. The materials contain a functionalized alkyl ethoxylate to reduce glistenings. ... | 01/31/2012 |
| 8105332 | Lens delivery system A lens delivery system handpiece having a threaded plunger rod with a ball lock ring. Locking the ring causes the plunger to be advanced by turning a thumbscrew or knob. Unlocking the ring allows the plunger to be advanced by pushing on the thumbscrew or knob in a m... | 01/31/2012 |
| 8101727 | Compositions and methods of use for antibodies of c-Met Antibodies and fragments that bind to the protein target c-Met, particularly to epitopes located in the c-Met extracellular domain, are provided, as are methods of use of the antibodies and kits, for treating an unwanted cell, in particular, a cell associated with a... | 01/24/2012 |
| 8101659 | Methods of treatment and pharmaceutical composition The invention relates a pharmaceutical composition comprising a combination of: (i) the AT 1-antagonist valsartan or a pharmaceutically acceptable salt thereof; and (ii) a NEP inhibitor or a pharmaceutically acceptable salt thereof and opti... | 01/24/2012 |
| 8101599 | Pharmaceutical composition containing anti-hypertensive agents The present invention relates to a combination of organic compounds, a pharmaceutical composition and a kit of parts comprising said combination of organic compounds and to a method of treatment or prevention of certain conditions or diseases. ... | 01/24/2012 |
| 8101182 | Methods and compositions for treating allergic diseases Disclosed in the present invention are antibodies that specifically recognize and antagonize human TSLP receptor, and methods of employing these antibodies to treat or ameliorate diseases or disorder mediated by TSLP signaling. ... | 01/24/2012 |
| 8100527 | Intermediate vision with phakic multifocal optics utilizing residual accommodations In one aspect, the present invention provides a method of correcting vision, which comprises determining a residual accommodation exhibited by a natural, crystalline lens of an eye, and selecting a multifocal intraocular lens (IOL), which exhibits a far-focus optica... | 01/24/2012 |
| 8097716 | Interfering RNA duplex having blunt-ends and 3′-modifications The present invention relates to double-stranded RNA compounds with at least one blunt end comprising at least one 3′-end of formula wherein X is O or S ... | 01/17/2012 |
| 8097617 | Organic compounds New compounds of the Formula (I): for the treatment of non-insulin-dependent diabetes mellitus. ... | 01/17/2012 |
| 8097270 | Use of nanoparticles as carriers for biocides in ophthalmic compositions The use of nanoparticles of inorganic materials (e.g., synthetic smectite clays) in ophthalmic compositions is described. The nanoparticles are utilized as biologically inert carriers or depots for biocides. The nanoparticles are particularly useful in preventing or... | 01/17/2012 |
| 8093406 | Cyclic sulfones with aminobenzyl substitution useful as BACE inhibitors The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, to their use as medicaments and to ... | 01/10/2012 |
| 8093259 | 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]-benzamide for treatment of melanoma The present invention relates to the use of pyrimidylaminobenzamide compounds for the preparation of a drug for the treatment of diseases that respond to modulation of Ephrin receptor kinase, especially EphB4, activity, especially for the curative and/or prophylacti... | 01/10/2012 |
| 8093220 | Combination of an HDAC inhibitor and an antimetabolite The invention relates to a combination which comprises: (a) a HDAI; and (b) an anti-metabolite, for simultaneous, concurrent, separate or sequential use, especially for use in the treatment of proliferati... | 01/10/2012 |
| 8093034 | Fed batch culture methods for streptococci This invention relates to the optimization of culture conditions to improve the production of bacterial capsular polysaccharides from Streptococcus strains in fed-batch culture. ... | 01/10/2012 |
| 8092813 | Polychlorinated biphenyls and squalene-containing adjuvants When using squalene in a vaccine adjuvant, there is a possibility of contamination with polychlorinated biphenyls (PCBs). Environmental exposure to PCBs may adversely affect children's immune responses to routine vaccinations. Thus the invention uses squalene with l... | 01/10/2012 |
| 8092724 | Method for making contact lenses The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming ... | 01/10/2012 |
| 8091568 | Temporal photo-bleaching of colored lens care solutions and use thereof The present invention provides a lens care kit for disinfecting and cleaning contact lenses. The lens care kit of the invention allows customers to visually identify when their lenses are disinfected, clean, and ready to wear. The invention is relied on color change... | 01/10/2012 |
| 8088313 | Process for the manufacture of mouldings A measured amount of a material that is crosslinkable by impingement of a suitable form of energy, especially UV light, is introduced into a two-part mould of which the cavity determines the shape of a moulding to be produced. The two mould halves are held a small d... | 01/03/2012 |
| 8084600 | Short interfering ribonucleic acid (siRNA) with improved pharmacological properties Short interfering ribonucleic acid (siRNA) for oral administration, said siRNA comprising two separate RNA strands that are complementary to each other over at least 15 nucleotides, wherein each strand is 49 nucleotides or less, and wherein at least one of which str... | 12/27/2011 |
| 8084487 | Processes for the preparation of 4-oxo-octahydro-indole-1-carbocyclic acid methyl ester and derivatives thereof The present invention relates to a process for the production of carbamic acid (2-chloroethyl)(3-oxocyclohexyl)-alkyl ester enantiomers and of 1-carbalkoxy-4-ketoperhydroindole enantiomers. ... | 12/27/2011 |
| 8084463 | Quinuclidine derivatives and their use as muscarinic M3 receptor antagonists Compounds of Formula (I); in salt or zwitterionic form wherein R1, R2, R3 and R4 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by the muscarinic M3 receptor, espe... | 12/27/2011 |
| 8084450 | Organic compounds 3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the p... | 12/27/2011 |
| 8084448 | Organic compounds Compounds of the formula are inhibitors of protein tyrosine phosphatases (PTPases) and, thus, may be employed for the treatment of conditions mediated by PTPase activity. The compounds of the present invention may also be e... | 12/27/2011 |
| 8084054 | Bioerodible film for ophthalmic drug delivery Drug delivery film compositions containing a combination of a water-soluble, film-forming polymers and a fatty acid glyceride or ester are suitable for delivering ophthalmic drugs. ... | 12/27/2011 |
| 8080263 | Dispersion for pulmonary delivery of a bioactive agent Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that typically comprises a liquid fluorochemical. As density variations between ... | 12/20/2011 |
| 8080029 | System for actuation of a vitreous cutter Embodiments of systems and methods disclosed herein regard simplifying and improving the performance and reliability of pneumatic actuators operable to actuate surgical cutters or shears. Various embodiments include systems and methods for vitreous cutting apparatus... | 12/20/2011 |
