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| Number | Title | Issue Date |
| 8176705 | Nacre composites, methods of synthesis, and methods of use The present invention relates to a novel composite structure with enhanced toughness, which incorporates features mimicked from nacre (mother of pearl). The structure can be used in many industrial and clinical applications, including aeronautics (aircraft skin), th... | 05/15/2012 |
| 8163347 | High energy density nanocomposites and related methods of preparation Disclosed are metal oxide-polymer composites having a substrate comprising a metal oxide component, an aluminum oxide component, and a metallocene olefin polymerization catalyst component coupled to the substrate. The compositions can be used as thin films in an ins... | 04/24/2012 |
| 8163345 | Methods utilizing scanning probe microscope tips and products therefor or produced thereby The invention provides a lithographic method referred to as “dip pen” nanolithography (DPN). Capillary transport of molecules from the SPM tip to the solid substrate is used in DPN to directly write patterns consisting of a relatively small collection of molecul... | 04/24/2012 |
| 8158658 | Heteroaromatic selective inhibitors of neuronal nitric oxide synthase Compounds selectively inhibiting neuronal nitric oxide synthase (nNos), such compounds of a formula wherein the variables are defined, herein. ... | 04/17/2012 |
| 8158627 | Compositions and treatments using pyridazine compounds and cholinesterase inhibitors The invention relates to compositions, conjugates and methods comprising pyridazine compounds and cholinesterase inhibitors for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheime... | 04/17/2012 |
| 8157931 | Case hardenable nickel-cobalt steel An advanced secondary hardening carburized Ni—Co steel achieves an improved case hardness of about 68-69 Rc together with nominal core hardness of about 50 Rc. ... | 04/17/2012 |
| 8156610 | Writing assist device A writing assist device includes a hand-receiving body having an exterior surface with a convex contour for ergonomically receiving the palm and/or fingers of the hand of a user from underneath and a base adapted to easily move by pushing or pulling on a writing sur... | 04/17/2012 |
| 8148071 | Methods and compositions for isolating nucleic acid The present invention relates to compositions and methods for isolating and purifying nucleic acid. In particular, the present invention relates to methods of isolating nucleic acid from cells for use in further analysis. ... | 04/03/2012 |
| 8145760 | Methods and systems for automatic inference and adaptation of virtualized computing environments Certain embodiments of the present invention provide systems and method for automatic inference and adaptation of a virtualized computer environment. Certain embodiments of a system include a virtual topology and traffic inference framework tool adapted to monitor t... | 03/27/2012 |
| 8143181 | Nonlinear optic glassy fiber, methods of making and applications of the same A process for producing an optical glass fiber from crystal-glass phase material. In one embodiment, the process includes the step of providing a molten crystal-glass phase material in a container, wherein the temperature of the molten crystal-glass phase material i... | 03/27/2012 |
| 8138364 | Transparent conducting oxide thin films and related devices Transparent conducting oxide thin films having a reduced indium content and/or an increased tin content are provided. In addition, processes for producing the same, precursors for producing the same, and transparent electroconductive substrate for display panels and... | 03/20/2012 |
| 8138140 | Self-assembling peptide amphiphiles and related methods for growth factor delivery Amphiphilic peptide compounds comprising one or more epitope sequences for binding interaction with one or more corresponding growth factors, micellar assemblies of such compounds and related methods of use. ... | 03/20/2012 |
| 8135243 | Transparent conducting components and related electro-optic modulator devices New electro-optic (EO) phase modulator devices and geometries, as can be constructed using a transparent conductive component. ... | 03/13/2012 |
| 8131348 | Systems, methods and apparatuses of elastic light scattering spectroscopy and low coherence enhanced backscattering spectroscopy Systems, methods, and apparatuses of elastic light scattering spectroscopy and low-coherence enhanced backscattering spectroscopy are described here. An apparatus couple-able to a light source and a target object, to facilitate light transmission between the light s... | 03/06/2012 |
| 8128930 | Anti-ADDL antibodies and uses thereof The present invention relates to antibodies that differentially recognize multi-dimensional conformations of Aβ-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extr... | 03/06/2012 |
| 8124583 | Composition and method for self-assembly and mineralization of peptide-amphiphiles The present invention is directed to a composition useful for making homogeneously mineralized self assembled peptide-amphiphile nanofibers and nanofiber gels. The composition is generally a solution comprised of a positively or negatively charged peptide-amphiphile... | 02/28/2012 |
| 8118949 | Copper precipitate carburized steels and related method A carburized and tempered hardened steel structure includes an iron based steel alloy including from about 3.7 to about 6 wt % copper, from 6 to about 10 wt % cobalt and from about 1 to about 10 wt % of non-ferrous secondary carbide formation elements selected from ... | 02/21/2012 |
| 8114835 | Self-assembling peptide amphiphiles for tissue engineering The present invention provides for compositions and methods for creating self-assembled peptide amphiphile (PA) structures. In particular, the present invention provides for two and three-dimensional structures of crosslinked PA microtexture structures useful for ti... | 02/14/2012 |
| 8114834 | Self-assembling peptide amphiphiles The present invention provides for self-assembling peptide amphiphiles that are capable of forming nanofibers. In particular, the present invention provides for diacetylene peptide amphiphiles that find use as scaffolds for tissue growth or for drug delivery. ... | 02/14/2012 |
| 8114830 | Polypeptoid pulmonary surfactants The present invention provides spreading agents based on sequence-specific oligomers comprising a peptoid, a peptide-peptoid chimera, a retropeptoid or a retro(peptoid-peptide) chimera, and methods for using the same, including for the treatment of respiratory distr... | 02/14/2012 |
| 8114599 | Compositions and methods for free-solution conjugate nucleic acid analysis The present invention provides compositions and methods for performing free-solution conjugate analysis of nucleic acid molecules. For example, the present invention provides multiplexed single-base extension assays for genotyping. In particular, the present inventi... | 02/14/2012 |
| 8110432 | Gate-planarized thin film transistor substrates and related methods of fabrication Thin film transistor substrates with conductor components in conjunction therewith, and related methods of fabrication. ... | 02/07/2012 |
| 8110125 | Separation of carbon nanotubes in density gradients The separation of single-walled carbon nanotubes (SWNTs), by chirality and/or diameter, using centrifugation of compositions of SWNTs in and surface active components in density gradient media. ... | 02/07/2012 |
| 8109007 | Object profile sensing A method for sensing an object profile shape involves relatively sweeping (whisking or translating) in angular or translational increments an elongated whisker element having a deflectable cantilever region and an object so that the cantilever region bends as a resu... | 02/07/2012 |
| 8103076 | Method for transcatheter intra-arterial perfusion magnetic resonance imaging A method to serially determine changes in perfusion to tissues is provided. This method involves injecting contrast material into a catheter that is positioned in the blood supply proximal to the targeted tissue of interest, acquiring a time series of images that de... | 01/24/2012 |
| 8099792 | Methods and apparatus for spatially resolved photocurrent mapping of operating photovoltaic devices using atomic force photovoltaic microscopy Atomic force photovoltaic microscopy apparatus and related methodologies, as can be used to quantitatively measure spatial performance variations in functioning photovoltaic devices. ... | 01/17/2012 |
| 8099149 | MRI method for quantification of cerebral perfusion A method for calculating quantitative perfusion measurements using an MRI system includes a pulse sequence that acquires perfusion weighted images and additionally measures T1 values before and after the administration of a contrast agent. T1 v... | 01/17/2012 |
| 8097877 | Inorganic-organic hybrid thin-film transistors using inorganic semiconducting films Inorganic semiconducting compounds, composites and compositions thereof, and related device structures. ... | 01/17/2012 |
| 8093588 | Siloxane-polymer dielectric compositions and related organic field-effect transistors Dielectric compositions comprising siloxane and polymeric components, as can be used in a range of transistor and related device configurations. ... | 01/10/2012 |
| 8092620 | High strength austenitic TRIP steel An austenitic TRIP steel consisting essentially of, in weight %, 0.14 to 0.18% Al, 2.8 to 3.2% Ti, 23.5 to 23.8% Ni, 3.8 to 4.2% Cr, 1.1 to 1.3% Mo, 0.29 to 0.31% V, 0.01 to 0.015% B, 0.01 to 0.02% C, and balance Fe and incidental impurities exhibits combined high y... | 01/10/2012 |
| 8088774 | Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death A novel class of pyridazine compositions and related methods of use. ... | 01/03/2012 |
| 8084273 | Universal matrix The application relates to a method of depositing a patterning species from a nanoscopic tip to a substrate surface. The method is carried out at a sufficiently high humidity to facilitate the deposition. The deposition of the patterning species is facilitated by a ... | 12/27/2011 |
| 8080314 | Nanotube assembly Methods and articles providing for precise aligning, positioning, shaping, and linking of nanotubes and carbon nanotubes. An article comprising: a solid surface comprising at least two different surface regions including: a first surface region which comprises an ou... | 12/20/2011 |
| 8080262 | Encapsulated peptide amphiphile nanostructures The present invention provides compositions and methods for creating encapsulated peptide amphiphilic nanostructures useful in treating diseases. In particular, the present invention provides compositions and methods for preparing peptide amphiphile nanostructures t... | 12/20/2011 |
| 8070959 | Chalcogenide compounds with a clay-like cation-exchange capacity and methods of use Chalcogenide compounds with cation exchange capability and methods of using the compounds are described. Compounds of the general formula A2xMxSn3-xS6 are described wherein x is 0.1-0.95, A is Li+, Na+ | 12/06/2011 |
| 8067078 | Nacre composites, methods of synthesis, and methods of use The present invention relates to a novel composite structure with enhanced toughness, which incorporates features mimicked from nacre (mother of pearl). The structure can be used in many industrial and clinical applications, including aeronautics (aircraft skin), th... | 11/29/2011 |
| 8063047 | Pyridazine compounds and methods The invention relates to novel chemical compounds of Formula I compositions and methods of using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions com... | 11/22/2011 |
| 8063014 | Self-assembly of peptide-amphiphile nanofibers under physiological conditions The present invention provides a method of promoting neuron growth and development by contacting cells with a peptide amphiphile molecule in an aqueous solution in the presence of a metal ion. According to the method, the peptide amphiphile forms a cylindrical micel... | 11/22/2011 |
| 8062791 | Battery cathode A battery cathode comprises an electrode of silver, molybdenum, oxygen, fluorine and chlorine and having a higher discharge capacity expressed as milliampere hour per gram of material (mAh/g) available from silver reduction at a potential above 3V as compared to tha... | 11/22/2011 |
| 8058244 | Cyclic peptide antitumor agents Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells. ... | 11/15/2011 |
