Assignee: Northeastern University

Location: Boston, MA
No. of patents: 201

Number	Title	Issue Date
8173628	Steroidal antiestrogens and antiandrogens and uses thereof The present invention comprises the design, synthesis and development of a new class of chemotherapeutic agents for prophylactic and therapeutic treatments in a mammal, particularly a human, believed to be at risk of suffering from a hormone-responsive disorder. In ...	05/08/2012
8172577	System and method for knowledge transfer with a game An educational maze navigated through responses to questions provided at points in the maze enhances factual assimilation and retention for the user. The user selects responses to travel through the maze and is not immediately informed whether the selected responses...	05/08/2012
8142370	Electro-rheological fluid brake and actuator devices and orthotic devices using the same Electro-rheological fluid brake or actuator devices provide controllable resistance with or without inclusion of active torque output in either direction of rotation under manual or computer control. The brake and actuator devices are suitable for use in an orthotic...	03/27/2012
8076151	Ultra-sensitive temperature sensing and calorimetry Methods and apparatus for ultra-sensitive temperature sensing and calorimetry. Radiation is directed at a thin electrically conductive film having one or more small apertures. The incident radiation excites surface plasmons on a first surface of the electrically con...	12/13/2011
8031514	Bistable nanoswitch A non-volatile bistable nano-electromechanical switch is provided for use in memory devices and microprocessors. The switch employs carbon nanotubes as the actuation element. A method has been developed for fabricating nanoswitches having one single-walled carbon na...	10/04/2011
8025607	Instrumented handle and pedal systems for use in rehabilitation, exercise and training equipment A mechatronic exercise system, e.g., for rehabilitation, having instrumented handle and pedal systems and, preferably, an interactive virtual environment is disclosed. Alternatively, the instrumented handle and pedal systems are part of a virtual reality augmenting ...	09/27/2011
8016893	Gear bearing drive A gear bearing drive provides a compact mechanism that operates as an actuator providing torque and as a joint providing support. The drive includes a gear arrangement integrating an external rotor DC motor within a sun gear. Locking surfaces maintain the components...	09/13/2011
7966364	System and method for virtual server migration across networks using DNS and route triangulation A first virtual server is moved from a first network location to a second network location without interrupting service to users of the first virtual server. The state and data of the first virtual server are copied and transmitted to the second network location to ...	06/21/2011
7947511	Intensified neutral loss tags and use thereof in mass spectrometry Ultrasensitive detection of a chemical substance (analyte) by mass spectrometry is achieved by employing a molecular tag that yields an intense parent ion and then an intense daughter ion in a multi-stage mass spectrometer. ...	05/24/2011
7837646	Hydrocephalus shunt system quick connector assembly A shunt system quick connector assembly to quickly connect and disconnect a catheter to a hydrocephalus shunt system comprising a valve in a valve housing. The catheter is affixed to the quick connector assembly. The quick connector assembly snaps over an external b...	11/23/2010
7812305	Tandem differential mobility spectrometers and mass spectrometer for enhanced analysis The invention relates generally to systems, methods and devices for analyzing samples and, more particularly, to systems using tandem differential mobility spectrometers in combination with a mass analyzer to enhance the analysis process of constituents of a sample....	10/12/2010
7808716	Photonic crystal devices using negative refraction Negative refraction in photonic crystals and diffraction grating is used to design plano-concave lenses to focus plane waves. Microwave experiments are carried out to demonstrate negative refraction and the performance of these lenses. Demonstration of negative refr...	10/05/2010
7792570	Opto-acoustic signal detection with coherent confocal microscopy A microscopy apparatus includes a heating source to provide a pulse of heating energy focused on a target to heat a localized region of the target, such as human tissue, to generate motion. A measuring source provides a measuring light beam focused on the target. A ...	09/07/2010
7769487	Process and architecture of robotic system to mimic animal behavior in the natural environment A robotic architecture for capturing the autonomous performance advantages the animal models enjoy in the natural environment is disclosed. A biomimesis process is employed to allow selective utilization of basic physical components and adaptation of a common contro...	08/03/2010
7750869	Dielectric and magnetic particles based metamaterials RF-optical metamaterials with (±∈, ±μ) figures-of-merit of interest are constructed from coupled magnetic and dielectric multi-resonant multi-disks (finite-size cylinders) or multi-sphere lattices arranged in a periodic or a random fashion to offer tailored mag...	07/06/2010
7728253	Nano-particle trap using a microplasma A system and method employing a microplasma to electrically charge nano- or micro-particles in a gas phase and, subsequently, trap the charged particles within the microplasma using the microplasma's built-in electric fields are disclosed. Confinement of the particl...	06/01/2010
7687269	Method for efficient transport of small liquid volumes to, from or within microfluidic devices Methods are presented for realizing zero-dispersion segmented flow for transfer of small microfluidic samples onto or within microfluidic analysis or processing devices. Where fluidic systems are in whole or in part made of materials favorable to the zero-dispersion...	03/30/2010
7652773	Enhanced detection of acousto-photonic emissions in optically turbid media using a photo-refractive crystal-based detection system A system and method of detecting acousto-photonic emissions in optically turbid media that provide increased levels of detection sensitivity. The detection system includes an ultrasonic transducer, a laser, a photo-detector for detecting ultrasound-modulated laser l...	01/26/2010
7578915	Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or columns, with the option of further on-line automated sample fraction a...	08/25/2009
7563500	Functionalized nanosubstrates and methods for three-dimensional nanoelement selection and assembly The present invention provides a functionalized nanosubstrate or “nanotemplate” that is useful for selectively assembling nanoelements across a large area. The nanotemplate is capable of guiding the massive parallel assembly of nanoelements to fabricate a three-...	07/21/2009
7556969	Intensified neutral loss tags and use thereof in mass spectrometry Ultrasensitive detection of a chemical substance (analyte) by mass spectrometry is achieved by employing a molecular tag that yields an intense parent ion and then an intense daughter ion in a multi-stage mass spectrometer. ...	07/07/2009
7471450	Confocal reflectance microscope system with dual rotating wedge scanner assembly A confocal reflectance microscope system incorporates a dual-wedge laser scanner assembly. The scanner assembly incorporates a pair of rotatably mounted prisms, each prism having an angle selected to deviate a light beam from a light source by a desired angle. Each ...	12/30/2008
7409298	Matched filtration with experimental noise determination for denoising, peak picking and quantitation in LC-MS An improved system and method of analyzing sample data that increases the reliability of peak (compound) detection and identification in the presence of chemical and/or random noise. The sample analysis system includes a compound-separating unit for separating const...	08/05/2008
7323092	Multichannel microscale system for high throughput preparative separation with comprehensive collection and analysis While the present invention has been described in conjunction with a preferred embodiment, one of ordinary skill, after reading the foregoing specification, will be able to effect various changes, substitutions of equivalents, and other alterations to the compositio...	01/29/2008
7279326	Composition for delivery of a mitochondrial genome to a cell The invention provides composition and methods for delivering a composition according to the invention comprising a wild-type (wt) mitochondrial DNA (mtDNA) molecule to a mammalian cell. The wt-mtDNA molecule is a functional mtDNA molecule that includes the entire m...	10/09/2007
7272020	Isolated, current-fed, pulse width modulation, DC-DC converter A current-fed DC-DC converter has a topology that improves converter performance and operates an input inductor in continuous conduction mode. The configuration and operation of the converter produces reduced requirements for circuit component ratings and leads to f...	09/18/2007
7256669	Method of preparing electrical contacts used in switches Processes for preparing contacts on microswitches have been invented. The first is a wet process, involving the use of one or more acids, bases and peroxides, in some formulations diluted in water, to flush the contacts. The second process involves exposing the cont...	08/14/2007
7247230	Electrochemical synthesis and processing of conducting polymers in supercritical media The present invention deals with the electrochemical synthesis of electrically conductive polymers in supercritical fluids, for example supercritical CO2. The use of the supercritical fluid as a solvent results in the reduction or elimination of hazardous...	07/24/2007
7041839	Steroidal antiestrogens and antiandrogens and uses thereof The present invention comprises the design, synthesis and development of a new class of chemotherapeutic agents for prophylactic and therapeutic treatments in a mammal, particularly a human, believed to be at risk of suffering from a hormone-responsive disorde. In a...	05/09/2006
7034647	Integrated magnetics for a DC-DC converter with flexible output inductor An integrated magnetic assembly that allows the primary and secondary windings of a transformer and a separate inductor winding to be integrated on a unitary magnetic structure is disclosed. The unitary magnetic structure includes first, second, and third legs that ...	04/25/2006
7014837	Process for the production of nan-sized zeolite A Described is a process to synthesize nano-size Zeolite A from an amorphous gel precursor which can be synthesized via reaction of NaAlO2, NaOH, and tetraethoxysilane (TEOS). Zeolite A with particle sizes of ˜150 nm was made by transformation of the amorp...	03/21/2006
7011957	Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon The method of the invention is directed to the novel use of a diffusion chamber within which previously “uncultivatible” microorganisms can be isolated. Rather than attempting to replicate the natural environment of an unknown microorganism, the method of the in...	03/14/2006
6995987	DC—DC converters providing reduced deadtime A DC-DC power converter (100) that provides increased power density, reduced size, and reduced costs of manufacture. The DC-DC power converter (100) includes first and second input terminals (101, 102), a plurality of output terminals (116, 1...	02/07/2006
6952353	Integrated magnetic isolated two-inductor boost converter A two-inductor boost converter includes an integrated magnetic core having a three-legged flux-conducting element with an energy-storing gap, for example in the center leg. Two primary windings are disposed on respective legs, such as the outer legs, and are coupled...	10/04/2005
6939452	Parallel sample loading and injection device for multichannel microfluidic devices A sample load and injection device (10) includes sample introduction capillaries (11) attached to a microfluidic device (12). Sample introduction capillaries (11) are connected to sample introduction channels (18). Sample introduct...	09/06/2005
6940187	Robust controller for controlling a UPS in unbalanced operation A controller (236) for an uninterruptible power supply (UPS) compensates for harmonic distortion in the output current (224,26,228). The controller also provides a control vector (230) also with input from the adaptation processor (234).	09/06/2005
6936118	Process of forming a composite coating on a substrate Precursor-based methods for the production of metal-matrix composite (MMC) coatings on steel and aluminum substrates for improved wear, corrosion and oxidation resistance have been made. Wire and surface precursors are deposited on the substrate by controlled therma...	08/30/2005
6929731	Parallel array of independent thermostats for column separations A thermostat array including an array of two or more capillary columns (10) or two or more channels in a microfabricated device is disclosed. A heat conductive material (12) surrounded each individual column or channel in array, each individual column ...	08/16/2005
6917165	Low power plasma generator A low power plasma generator is provided which can be fabricated in micro-miniature size and which is capable of efficient portable operation. The plasma generator comprises a microwave stripline high Q resonant ring, which may be circular or non-circular, disposed ...	07/12/2005
6885970	Saliency-based position estimation in permanent magnet synchronous motors A method and system for the sensorless estimation of the states of the mechanical subsystem of a motor are disclosed. In particular, the method and system split the estimation problem into two sub-problems: the estimation of motor parameters as a function of positio...	04/26/2005

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Assignee: Northeastern University