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Assignee: Nicox S.A.


Location: Sophia Antipolis - Valbonne, FR
No. of patents: 12

NumberTitleIssue Date
7825263Nitrooxyderivatives of carvedilol and other beta blockers as antihypertensive
The present invention relates to β-adrenergic blockers nitrooxyderivatives of general formula (I): A-(Y—ONO2)s and enantiomers and diastereoisomers and pharmaceutically acceptable salts thereof, pharmaceutical compositio...
11/02/2010
7723529Process for preparing nitrooxy esters, nitrooxy thioesters nitrooxy carbonates and nitrooxy thiocarbinates, intermediates useful in said process and preparation thereof
The present invention relates to a process for preparing nitrooxy esters, nitrooxy thioesters, nitrooxy carbonates and nitrooxy thiocarbonates of compounds having at least an hydroxyl or thiol functional group, according to the following reaction scheme
05/25/2010
7723382Process for preparing nitrooxyalkyl substituted esters of carboxylic acids, intermediates useful in said process and preparation thereof
The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of a drug and R1-R12 are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer from 0 to 6, an...
05/25/2010
7642289Drugs for chronic pain
The present invention relates to nitrooxyderivatives or salts thereof having the following general formula (I): R—NR1c—(K)k0—(B)b0—(C)c0—NO2  (I) wherein ...
01/05/2010
7605151Nitrate esters of corticoid compounds and pharmaceutical applications thereof
Compounds of the formula and use of the compounds as medicaments. ...
10/20/2009
7399878Pharmaceutical compounds
Compounds or their salts of general formula (I): A-B-N(O)s wherein: s is an integer equal to 1 or 2; A=R-T1-, wherein R is the drug radical and T1=(CO)t or (X)t′, wherein X=O, S, NR1c, R1c
07/15/2008
7378437Drugs for diabetes
Use for the diabetes treatment of compounds or salts thereof, having the following general formula (I): A-(B)b0—(C)c0—NO2 wherein A contains the radical of a drug having an antiinflammatory or analgesic activity, B is a bivalent ...
05/27/2008
7378412Pharmaceutical compounds
Compounds or their salts having general formula: A-B—C—NO2 wherein: A is a drug radical; B is a linker; and C is a bivalent radical. ...
05/27/2008
7368442Nitrate esters of corticoid compounds and pharmaceutical applications thereof
Compounds of the formula and use of the compounds as medicaments. ...
05/06/2008
7217733ACE inhibitor derivatives
ACE inhibitor nitroderivatives of formula (I): A—(X1—ONO2)s   (I) having wider pharmacological activity and enhanced tolerability. They can be employed for treating cardiovascular and renal diseases and in...
05/15/2007
7205288Nitrate esters of corticoid compounds and pharmaceutical applications thereof
Compounds of the formula and use of the compounds as medicaments. ...
04/17/2007
7199258Process for preparing nitrooxyderivatives of naproxen
The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of naproxen or bromonaproxen and R1–R12 are hydrogen or alkyl groups, m, n, o, q, r and s are ea...
04/03/2007
 
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