...that two musicians were responsible for the invention of color print film? Fascinated by photography, Leopold Godowsky and Leopold Mannes worked together to produce an easy-to-use, practical color film. They worked full time as music teachers and gave concerts while experimenting during their off hours in Mannes' kitchen. Their success earned them full-time, well-paying jobs at Kodak and their efforts resulted in Kodachrome film, which was introduced in 1935.
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| Number | Title | Issue Date |
| 8003656 | 2-phenoxy pyrimidinone analogues 2-Phenoxy pyrimidinone analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are parti... | 08/23/2011 |
| 7935702 | Substituted biaryl quinolin-4-ylamine analogues Substituted biaryl quinolin-4-ylamine analogues of Formula I are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment o... | 05/03/2011 |
| 7851474 | Dipiperazinyl ketones and related analogues Dipiperazinyl ketones and related analogues are provided, as are methods for their preparation and use. Such compounds may generally be used to modulate ligand binding to histamine H3 receptors in vivo or in vitro, and are particularly useful in the treatment of a v... | 12/14/2010 |
| 7795262 | Piperazinyl oxoalkyl tetrahydroisoquinolines and related analogues Piperazinyl oxoalkyl tetrahydroisoquinolines and related analogues of the Formula: are provided, in which variables are as described herein. Such compounds may be used to modulate ligand binding to histamine H3 receptors in... | 09/14/2010 |
| 7728009 | Thiazole amides, imidazole amides and related analogues Thiazole amides, imidazole amides and related analogues of the Formula: are provided, in which variables are as described herein. Such compounds may be used to modulate ligand binding to histamine H3 receptors in vivo or in... | 06/01/2010 |
| 7662830 | Substituted biaryl piperazinyl-pyridine analogues Substituted biaryl piperazinyl-pyridine analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptors activity in vivo or in vi... | 02/16/2010 |
| 7642267 | Benzimidazole and pyridylimidazole derivatives This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I. The invention is particularly related to such compounds that bind with high selectivity and high affinity to the ben... | 01/05/2010 |
| 7566712 | Biaryl piperazinyl-pyridine analogues Biaryl piperazinyl-pyridine analogues are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are ... | 07/28/2009 |
| 7488740 | Substituted quinolin-4-ylamine analogues Substituted quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation... | 02/10/2009 |
| 7432275 | Carboxylic acid, phosphate or phosphonate substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators Acid-substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor act... | 10/07/2008 |
| 7371752 | Aryl fused substituted 4-oxy-pyridines Disclosed are compounds of the formula: wherein X, Q, W and are as defined herein. These compounds are agonists, antagonists or inverse agonists for GABAA brain recepto... | 05/13/2008 |
| 7351826 | Aryl acid pyrimidinyl methyl amides, pyridazinyl methyl amides and related compounds The invention provides compounds of Formula (I) that bind to GABAA receptors. In the above formula, variables are defined herein. Such compounds may be used to modulate ligand binding to GABAA receptors in vivo or in vitro, and are particularly... | 04/01/2008 |
| 7348326 | Heteroaryl fused aminoalkyl imidazole derivatives: selective modulators of GABAreceptors Disclosed are compounds of the formula: or the pharmaceutically acceptable non-toxic salts thereof wherein the A, B, C, D, X, R1, R2, R3, R4, R5, and R6, are... | 03/25/2008 |
| 7342115 | 3-substituted-6-aryl pyridines 3-substituted-6-aryl pyridines of Formula I are provided: wherein R1, R2, R3, R8, R9, A and Ar are defined herein. Such compounds are ligands of C5a receptor. Preferred... | 03/11/2008 |
| 7329664 | Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with ... | 02/12/2008 |
| 7326709 | Bicyclic and tricyclic heteroaromatic compounds Disclosed are compounds of the formula: and the pharmaceutically acceptable salts thereof, wherein W, Q, X, X1, Y and Z are as defined herein. These compounds bind with high selectivity and/or high aff... | 02/05/2008 |
| 7323478 | Melanin concentrating hormone receptor ligands Disclosed are compounds of the formula: and the pharmaceutically acceptable salts thereof wherein Q, X, Y, Z, and R1 R9, and R12-R19 are defined herein. These c... | 01/29/2008 |
| 7304059 | Substituted quinazolin-4-ylamine analogues Substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activati... | 12/04/2007 |
| 7300945 | Benzimidazole and pyridylimidazole derivatives This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I The invention is particularly related to such compounds that bind... | 11/27/2007 |
| 7291621 | Substituted biaryl amides C5a receptor modulators Substituted biaryl amides of Formula I are provided. Such compounds are ligands that may be used to modulate C5a receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological C5... | 11/06/2007 |
| 7282498 | Substituted fused pyrroleoximes and fused pyrazoleoximes Disclosed are compounds of the formula and the pharmaceutically acceptable salts thereof wherein R, Ar, A, n, R1 and R2 are defined herein. These compounds are highly selective agonists, ant... | 10/16/2007 |
| 7271270 | High affinity small molecule C5a receptor modulators This invention relates to low molecular weight, non-peptidic, non-peptidomimetic, organic molecules that act as modulators of mammalian complement C5a receptors, preferably ones that act as high affinity C5a receptor ligands and also to such ligands that act as anta... | 09/18/2007 |
| 7271170 | Imidazo-pyrimidines and triazolo-pyrimidines: benzodiazepine receptor ligands Compounds of Formula I are provided, as are methods for their preparation. The variables Z1, Z2, Z3, R4, R5, R6, R7, R8 and ... | 09/18/2007 |
| 7253168 | Substituted 1-benzyl-4-substituted piperazine analogues Compounds of Formula I are provided, in which variables are as described herein: Such compounds may be used to modulate MCH binding to MCH receptors in vivo or in vitro, and are particularly useful in the treatment... | 08/07/2007 |
| 7241765 | Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues Melanin concentrating hormone receptor ligands (especially 1-benzyl-4-aryl-piperazines, 1-benzyl-4-aryl-piperidines and related compounds), capable of modulating MCH receptor activity, are provided. Such ligands may be used to modulate MCH binding to MCH receptors i... | 07/10/2007 |
| 7223778 | 5-substituted-2-arylpyridines Novel 5-substituted-2-arylpyridine compounds are provided. Such compounds can act as selective modulators of CRF receptors. The 5-substituted-2-arylpyridine compounds provided herein are useful in the treatment of a number of CNS and periphereal disorders, particula... | 05/29/2007 |
| 7202250 | Substituted arylpyrazines Arylpyrazine compounds are provided, including arylpyrazines that can bind with high affinity and high selectivity to CRF1 receptors, including human CRF1 receptors. The invention thus includes methods for treatment of disorders and diseases as... | 04/10/2007 |
| 7186734 | Aryl imidazoles and related compounds as C5a receptor modulators The invention provides Aryl substituted imidazoles, pyrazoles, pyridizines and related compounds of the Formula where the variables are defined herein. Such compounds are ligands of C5a receptors. Preferr... | 03/06/2007 |
| 7179807 | 5-substituted-2-arylpyrazines Novel 5-substituted-2-arylpyrazine compounds are provided. Such compounds can act as selective modulators or CRF receptors. Compounds of the invention are provided by the following formula: The 5-substituted-2-aryl... | 02/20/2007 |
| 6432946 | 3-aminoalkylamino-2H-1,4-benzoxazines and 3-aminoalkylamino-2H-1,4-benzothiazines: dopamine receptor subtype specific ligands Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof, wherein: Ar represents aryl or heteroaryl; R1 and R2 are the same or different and represent organic or inorganic substituent... | 08/13/2002 |