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| Number | Title | Issue Date |
| 7943729 | Dominant B cell epitopes and methods of making and using thereof Disclosed are methods for obtaining at least one epitope suitable for detecting the presence of an antibody against a tumor associated antigen of a cancer in a sample. Kits, assays, and substrates employing the epitopes of the present invention are disclosed. Also d... | 05/17/2011 |
| 7420032 | Dominant B cell epitopes and methods of making and using thereof Disclosed are methods for obtaining at least one epitope suitable for detecting the presence of an antibody against a tumor associated antigen of a cancer in a sample. Kits, assays, and substrates employing the epitopes of the present invention are disclosed. Also d... | 09/02/2008 |
| 7384908 | Orally active peptides that prevent cell damage and death This invention provides an ADNF polypeptide comprising an active core site, the active core site comprising at least one D-amino acid. The invention also provides a pharmaceutical composition comprising an ADNF polypeptide comprising an active core site, the active ... | 06/10/2008 |
| 7262018 | Agents that bind to and inhibit human cytochrome P450 2C19 The invention provides monoclonal antibodies and other binding agents to human cytochrome P450 2C19 having advantageous properties, including capacity substantially to inhibit enzyme activity of human cytochrome P450 2C19 and lack of specific binding to other human ... | 08/28/2007 |
| 6993959 | System and method for the analysis of atomic force microscopy data A system and method for the analysis of AFM data is provided. The system and method can be used in conjunction with an atomic force microscopy (AFM) system including a cantilever with a tip used to analyze a sample, the AFM outputting an AFM data file. An exemplary ... | 02/07/2006 |
| 6908738 | Agents that bind to and inhibit human cytochrome P450 2C19 The invention provides monoclonal antibodies and other binding agents to human cytochrome P450 2C19 having advantageous properties, including capacity substantially to inhibit enzyme activity of human cytochrome P450 2C19 and lack of specific binding to other human ... | 06/21/2005 |
| 6825206 | Camptothecin compounds with a thioether group Camptothecin compounds which are effective anti-tumor compounds are disclosed. These conjugates inhibit the enzyme topoisomerase I and enhance the stability of the topoisomerase I-DNA cleavable complex. ... | 11/30/2004 |
| 6670176 | Adeno-associated virus capable of expressing factor IX protein and cells comprising the same The subject invention concerns a recombinant adeno-associated virus vector characterized as being capable of delivering and expressing at least one mammalian gene into a genome of a mammalian host cell such that the expression of the gene is regulated in ... | 12/30/2003 |
| 6551585 | Use of tumor necrosis factor as an adjuvant Tumor necrosis factors, alone or together with cytokines such as IL-1 or IFN-γ, are capable of serving as non-toxic vaccine adjuvants.... | 04/22/2003 |
| 6545002 | Substituted 8-phenylxanthines useful as antagonists of A2B adenosine receptors The present invention provides compounds having the formula I: ##STR1## X is (C1 -C8)alkylene, (C2 -C8)alkenylene, (C2 -C8)alkynylene, wherein one of the carbon atoms in the alkylene, alken... | 04/08/2003 |
| 6419639 | Laparoscopic SAC holder assembly This invention relates to a surgical device and methods for accessing and retrieving a tissue mass from a body cavity through a minimally invasive laparoscopic procedure. The device consists of a handle comprising an inner rod, which is rotatably engaged ... | 07/16/2002 |
| 6383761 | Methods and compositions for identifying modulators of G-protein-coupled receptors The present invention provides methods and compositions that can be used to identify modulators of G-protein-coupled receptors.... | 05/07/2002 |
| 6274134 | Human cell adhesion protein AAMP-1 and uses thereof The present invention relates, in general, to AAMP-1, and to a peptide derived from the amino-terminal region of AAMP, P189. In particular, the present invention relates to a DNA segment encoding AAMP-1, P189 or fragments thereof; polypeptides encoded by ... | 08/14/2001 |
| 6031074 | Automated Peptide design and synthesis An automated peptide design and synthesis method is provided, wherein peptides are synthesized on interior, inward facing surfaces of reservoirs formed in a solvent resistant substrate. Novel substrates, as well as novel solutions for storing protected ca... | 02/29/2000 |
| 5965531 | Method of reducing perivascular lesions using insulin-like growth factor I A disease or disorder associated with myelin injury, such as multiple sclerosis, is treated by administering to a patient in need thereof an effective amount of insulin-like growth factor I (IGF-I). The method reduces blood brain and blood nerve barrier p... | 10/12/1999 |
| 5859019 | Methods for protecting against cardiac ischemia by administering adenosine A2a receptor antagonists Methods for reducing or preventing ischemic damage of the heart are disclosed. A preferred embodiment of the invention comprises the administration of a specific A2a receptor antagonist, 8-(3-chlorostyryl) caffeine, to patients suffering from i... | 01/12/1999 |
| 5401755 | N-(1-thienylcycloalkyl)alkenylamines for treatment of neurotoxic injury Compounds, compositions and methods of treatment are described to control brain damage associated with anoxia or ischemia which typically follows stroke, cardiac arrest or perinatal asphyxia. The treatment includes administration of an N-(1-thienylcycloal... | 03/28/1995 |
