Assignee: Monell Chemical Senses Center

Location: Philadelphia, PA
No. of patents: 33

Number	Title	Issue Date
8173769	Taste receptors of the T1R family from domestic cat The present invention relates to the discovery of several genes of the domestic cat (Felis catus) associated with taste perception. The invention provides, inter alia, the nucleotide sequence of the feline Tas1r1, Tas1r2, and Tas1r3 receptor genes, the amino ...	05/08/2012
8168395	Taste receptors of the T1R family from domestic dog The present invention relates to the discovery of several genes of the domestic dog (Canine familiaris) associated with taste perception. The invention provides, inter alia, the nucleotide sequence of the canine Tas1r1, Tas1r2, and Tas1r3 receptor genes, the ...	05/01/2012
8030068	Method for culturing mammalian taste cells The invention provides methods of culturing mammalian taste cells, including taste receptor cells. Cells are maintained for a duration of up to three months and longer while maintaining molecular and functional characteristics of mature taste cells. The cells are cu...	10/04/2011
8008084	Method for determining whether or not a mammal is affected with a lung cancer The present invention relates to a method for determining whether or not a mammal is affected with a lung cancer. The method for determining whether or not a mammal is affected with a lung cancer of the present invention includes the steps of: ...	08/30/2011
7977054	Single walled carbon nanotubes functionally adsorbed to biopolymers for use as chemical sensors Chemical field effect sensors comprising nanotube field effect devices having biopolymers such as single stranded DNA functionally adsorbed to the nanotubes are provided. Also included are arrays comprising the sensors and methods of using the devices to detect vola...	07/12/2011
7892756	Human salty taste receptor and methods of modulating salty taste perception Methods for identifying modulators of the epithelial sodium ion channel and for identifying modulators of salty taste perception are described. Also featured are isolated human salty taste receptors, artificial lipid bilayers comprising an epithelial sodium ion chan...	02/22/2011
7785807	Voltage-gated, pH-sensitive anion channel and its novel splice variant involved in taste sensation The invention provides a novel splice-variant of the ClC-4 protein, termed ClC-4A. ClC-4A is expressed in taste bud cells and is involved in sour taste perception. The invention provides ClC-4A polynucleotides and ClC-4A polypeptides, vectors, host cells and ClC-4A ...	08/31/2010
7763238	Olfactory adaptation and cross-adapting agents to reduce the perception of body odors Deodorant compositions are disclosed comprising a cross-adapting agent, alone or in combination with other such agents, in an amount effective to reduce perception of malodor. Deodorant compositions are also disclosed comprising a cross-adapting agent, alone or in c...	07/27/2010
7541158	Taste receptors of the T1R family from domestic dog The present invention relates to the discovery of several genes of the domestic dog (Canine familiaris) associated with taste perception. The invention provides, inter alia, the nucleotide sequence of the canine Tas1r1, Tas1r2, and Tas1r3 receptor genes, the ...	06/02/2009
7527944	Taste receptors of the T1R family from domestic cat The present invention relates to the discovery of several genes of the domestic cat (Felis catus) associated with taste perception. The invention provides, inter alia, the nucleotide sequence of the feline Tas1r1, Tas1r2, and Tas1r3 receptor genes, the amino ...	05/05/2009
7488599	Methods for culturing mammalian taste cells The invention provides methods of culturing mammalian taste cells, including taste receptor cells. Cells are maintained for a duration of up to three months and longer while maintaining molecular and functional characteristics of mature taste cells. The cells are cu...	02/10/2009
7056948	Use of odor reducing and cross-adapting agents to reduce animal waste malodors Methods and compositions for reducing animal waste malodor using agents and cross-adapting agents are described. ...	06/06/2006
6782733	Method for estimating the change of body smell with ageing It is desirable to provide a gas chromatography type of chemical analysis method for estimating the change of body smell with progressive ageing of a living subject over a period of years by 1) utilization of the smell distinguishing ability of an experimental anima...	08/31/2004
6506801	Methods of treating anosmia and repopulating olfactory nerves with retinoids The present invention provides methods of treating complicated anosmia in a mammal, methods of enhancing the rate of olfactory nerve recovery in a mammal, and methods of enhancing nerve regeneration in a mammal by administering an effective amount of a re...	01/14/2003
6150409	Adjuvants and methods for raising intracellular calcium ion concentration Adjuvants for preventing adaptation to odors comprising one or compounds having the following formula (1): ##STR1## wherein R1 is a C1 to C8 lower alkyl group or a C7 to C9 aralkyl group, and R2 is a hydrogen atom or a C1 to C8 lower alkyl group, are...	11/21/2000
5877223	Naturally-occurring odoriferous animal repellent Certain volatile compounds naturally present in herring gull eggs are effective for repelling animals and birds, particularly canids, from the locus to which such compounds are applied. More particularly, the volatile compounds which are effective animal ...	03/02/1999
5811256	Method for measuring sensory irritation in vitro Methods for ascertaining the sensory irritation of chemicals in vitro are described. The methods include the cultivation of neuronal cells alone, with target tissue cells, and with target tissue cells and mast cells; the introduction of a chemical to be t...	09/22/1998
5672352	Methods of identifying the avian repellent effects of a compound and methods of repelling birds from materials susceptible to consumption by birds There is provided by the invention a structure-activity model for identifying avian repellent compounds. It has now been found that certain topological and electronic features of a molecule, especially the presence of a core ring structure, the basicity o...	09/30/1997
5464625	Non-toxic methods of repelling rodents from materials susceptible to rodent consumption Methods of effectively repelling vertebrates, especially rodents, from consuming or utilizing materials otherwise susceptible to such consumption or utilization, using at least one non-toxic rodent repellent compound selected from the group comprising ace...	11/07/1995
4954531	Use of 2,5-anhydro-d-mannitol as a food intake modifier A novel method for altering the food intake of a mammal is diclosed wherein 2,5-anhydro-D-mannito (2,5-AM) is administered to that mammal in an amount sufficient to alter its food intake. Preferably, normal feeding and fasting periods, and most preferably...	09/04/1990
4931403	Axillary androstenol and dehydroepiandrosterone as fertile period onset indicators A novel method of determining the onset of the fertile period of a human female is disclosed comprising the step of monitoring the axillary secretions of said female during the course of her menstrual cycle to determine variations in the concentration of ...	06/05/1990
4888173	Anthocyanin bird repellents Anthocyanins have been found to be taste-aversive to avian species. This invention relates to mammalian livestock feeds and pelleted fertilizer and pesticide compositions each incorporating effective avian-repellent amounts of such anthocyanins or anthocy...	12/19/1989
4879244	Birth control method involving monitoring of axillary androstenol and dehydroepiandrosterone A novel method of determining the onset of the fertile period of a human female is disclosed comprising the step of monitoring the axillary secretions of said female during the course of her menstrual cycle to determine variations in the concentration of ...	11/07/1989
4871776	2,5-anhydro-1,6-dihalo-1,6-dideoxy-D-mannitol A novel fructose analog is disclosed which has been found to modify the food intake of mammals. If administered during the diurnal fasting period, the mammals increase their food intakes. If administered during the diurnal feeding period, food intake is d...	10/03/1989
4861585	Enhanced rodent edible with natural attractants A novel rodent edible is disclosed. The edible contains a conventional edible component, and an attractant naturally present in the breath of said rodents in an amount effective to increase the preference for said edible component to said rodents. Carbon ...	08/29/1989
4808626	Use of 2,5-anhydro-D-mannitol as a food intake modifier A novel method for altering the food intake of a mammal is disclosed wherein 2,5-anhydro-D-mannitol (2,5-AM) is administered to that mammal in an amount sufficient to alter its food intake. Preferably, normal feeding and fasting periods, and most preferab...	02/28/1989
4772559	Method of detecting the presence of bronchogenic carcinoma by analysis of expired lung air A novel method of detecting and diagnosing lung cancers by monitoring and analyzing expired lung air for the presence of selected aromatic amines, particularly aniline and ortho-toluidine, is provided....	09/20/1988
4693897	Stimulation and enhancement of feeding in herbivorous fish Methods for stimulating or enhancing feeding of herbivorous fish are disclosed comprising presenting the fish with an edible composition comprising a stimulatory amount of at least one of aspartic acid, glutamic acid or citric acid. In accordance with a p...	09/15/1987
4670401	Axillary androstenol and dehydroepiandrosterone as fertile period onset indicators Method for determining the onset of the fertile period of a human female comprising the step of monitoring the axillary secretions of said female during the course of her menstrual cycle to determine variations in the concentration of androstenol or dehyd...	06/02/1987
4542097	Production of gamma-lactone, rich flavor additives by Pityrosporum species cultured on lipid rich substrates Novel odor-flavor materials and methods for producing the same are disclosed comprising a mixture of various gamma-lactones. In the preferred embodiment, a member of the genus Pityrosporum is cultured on a culture medium and is stimulated to produce a gam...	09/17/1985
4467814	Method for detecting bovine estrus by determining methyl heptanol concentrations in vaginal secretions A novel method for determining when cows are in estrus is disclosed comprising the step of monitoring the vaginal secretions of a cow to determine an increase in the amount of an indicator compound in said secretions. A significant increase in the amount ...	08/28/1984
4385125	Method detecting ovulation by monitoring dodecanol concentration in saliva Method for precisely ascertaining the time of ovulation by monitoring the concentration of alcohols in the range of C10 -C16, particularly dodecanol. A spike in the concentration of such compound(s) is indicative of time of ovulation...	05/24/1983
4334540	Method of diagnosing periodontal disease through the detection of pyridine compounds A novel method of diagnosing periodontal disease is disclosed wherein telltale pyridine and alkyl-pyridine compounds which are detected in the oral cavity are indicative of periodontal disease. An alternate embodiment method is disclosed wherein increased...	06/15/1982

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Assignee: Monell Chemical Senses Center