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| Number | Title | Issue Date |
| 5278048 | Methods for detecting the effect of cell affecting agents on living cells Methods are disclosed for detecting the effects of cell affecting agents on living cells. The method steps include providing living cells that are retained in a micro flow chamber. The micro flow chamber is adapted for either continuous or intermittent fl... | 01/11/1994 |
| 5164319 | Multiple chemically modulated capacitance determination Apparatus and methods are provided for multiple detection of analytes employing semiconductor capacitance as the signal modulated by the analyte. A plurality of semiconductor capacitors are organized for detection (at individual sites) of changes in capac... | 11/17/1992 |
| 5004806 | Nitrocellulose filtration to remove proteins from polynucleotides The present invention encompasses a method for removing proteins from a solution containing polynucleotides and proteins comprising filtering the solution through a nitrocellulose membrane at neutral or basic pH.... | 04/02/1991 |
| 4978608 | DNA detection system Picogram amounts of DNA can be detected in a sample by the use of high affinity single-stranded DNA binding proteins. The assay is applicable not only to pure DNA samples but also to samples containing significant amounts of protein.... | 12/18/1990 |
| 4968148 | Single source multi-site photometric measurement system A multibeam photometric measuring device includes a single light source along with a filter assembly for passing only a desired band of wavelengths and an optical system for suitably focusing light from the light source. Light is transmitted individually ... | 11/06/1990 |
| 4963658 | DNA detection method Picogram amounts of DNA can be detected in a sample by the use of high-affinity, single-stranded DNA binding proteins. The assay is applicable not only to pure DNA samples but also to samples containing significant amounts of protein.... | 10/16/1990 |
| 4963815 | Photoresponsive electrode for determination of redox potential Devices and methods are provided for determining the presence and amount of an analyte by measuring a redox potential-modulated photoinducing signal from a photoresponsive element. Further devices and methods are provided for determining the presence and ... | 10/16/1990 |
| 4956275 | Migratory detection immunoassay Novel methods and devices are provided for detecting analytes, where the sample is placed upstream from a reagent which is a component of a signal-producing system. The detection zone is provided upstream from the sample, where the amount of reagent which... | 09/11/1990 |
| 4942127 | Polyredox couples in analyte determinations Enzyme or substrate determinations can be achieved by employing an organic second substrate, which produces a product which may be coupled with a metal inorganic redox couple capable of interacting with and affecting the potential of a metal electrode on ... | 07/17/1990 |
| 4883579 | Photoresponsive redox detection and discrimination Devices and methods are provided for making a plurality of determinations of the local (site-specific) redox state of a liquid system, by employing a photoresponsive element, which can be independently irradiated at different sites to provide independentl... | 11/28/1989 |
| 4849330 | Photoresponsive redox detection and discrimination Devices and methods are provided for making a plurality of determinations of the local (site-specific) redox state of a liquid system, by employing a photoresponsive element, which can be independently irradiated at different sites to provide independentl... | 07/18/1989 |
| 4758786 | Method of analyzing semiconductor systems A method of analyzing selected regions of semiconductor systems to determine the uniformity of distribution of trapped charges or electric dipoles at the surface of the semiconductor or in a dielectric or insulating material associated therewith, the meth... | 07/19/1988 |
| 4741619 | Hydrophilic microplates for vertical beam photometry A microtiter plate prepared from a hydrophobic plastic is rendered more hydrophilic by treatment of the surfaces of the wells of the microplate prior to use. The resulting plates are particularly useful in vertical beam photometry.... | 05/03/1988 |
| 4737464 | Solid-state optical assay imaging apparatus An apparatus for determining a characteristic of a signal modulating component related to an analyte of interest at an assay site by measuring light modulated by the component. A light source uniformly illuminates the assay site and a reference site. The ... | 04/12/1988 |
| 4704353 | Photoresponsive redox detection and discrimination Devices and methods are provided for making a plurality of determinations of the local (site-specific) redox state of a liquid system, by employing a photoresponsive element, which can be independently irradiated at different sites to provide independentl... | 11/03/1987 |
| 4591550 | Device having photoresponsive electrode for determining analytes including ligands and antibodies Photoresponsive devices, including a photoresponsive electrode, are provided and methods for their use to measure changes in environment at a site at or about the surface of the photoresponsive device. By employing a source of light for irradiating a site... | 05/27/1986 |
| 4490216 | Lipid membrane electroanalytical elements and method of analysis therewith Electroanalytical elements are provided involving a polarity-sensitive layer; a first lipid layer non-diffusively bound to said polarity-sensitive layer; and, a second amphiphilic layer, with hydrophilic heads distal from said first lipid layer and defini... | 12/25/1984 |
