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| Number | Title | Issue Date |
| 7323543 | Multiple agent diabetes therapy A pharmaceutical composition includes at least two of agents I)-iii), wherein agent i) is selected from the group consisting of an insulin, an insulin analog, a physiologically active fragment of said insulin and a physiologically active fragment of said insulin ana... | 01/29/2008 |
| 7150655 | Test plug and cable for a glucose monitor Methods and apparatuses for electrically connecting a medical glucose monitor to a glucose sensor set, as well as for testing the operation of the glucose monitor, monitor cable and glucose sensor set are provided. In one embodiment, an electric cable comprises a ca... | 12/19/2006 |
| 6880242 | Method for circuit protection during radiation sterilization A circuit protection device for protection of sensitive components during high energy radiation sterilization that includes a support substrate and a protective housing. The substrate supports the sensitive components. The protective housing is hermetically coupled ... | 04/19/2005 |
| 6811659 | Microelectrogravimetrically plated biosensors and apparatus for producing same Disclosed is a method for microelectrogravimetrically depositing an electroactive species onto an electrode or a plurality of electrodes comprising dispensing a solution containing the electroactive species from a microdispenser to form a hanging drop of the solutio... | 11/02/2004 |
| 6804544 | Detection of biological molecules using chemical amplification and optical sensors Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is... | 10/12/2004 |
| 6784274 | Hydrophilic, swellable coatings for biosensors Methods for reducing the electrode impedance of implantable biosensors by coating the surface of the biosensor with a uniform hydrogel which allows unimpeded water movement around the sensor are provided. The surface coatings are compositions which are biocompatible... | 08/31/2004 |
| 6750311 | Detection of biological molecules using boronate-based chemical amplification and optical sensors Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where the system is... | 06/15/2004 |
| 6594156 | Device and method for circuit protection during radiation sterilization A circuit protection device for protection of sensitive components during high energy radiation sterilization that includes a support substrate and a protective housing. The substrate supports the sensitive components. The protective housing is hermetical... | 07/15/2003 |
| 6585695 | Reservoir connector A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. A base is provided which is adapted to receive a reservoir. The base has a base engagement member, such as a detent, p... | 07/01/2003 |
| 6555986 | Method and apparatus for detection of occlusions A method and apparatus for automatically detecting an occlusion or drive system failure in a medication infusion system is provided. The electrical current to an infusion pump is measured and compared against a baseline average current. If the current exc... | 04/29/2003 |
| 6475196 | Subcutaneous infusion cannula Provided is an infusion cannula modified to incorporate one of more medicinal agents. The infusion cannula has a tube having an inner lumen and an external surface, and is made of a flexible, biologically compatible elastomeric material, with a coating ad... | 11/05/2002 |
| 6462162 | Hydrophilic, swellable coatings for biosensors Methods for reducing the electrode impedance of implantable biosensors by coating the surface of the biosensor with a uniform hydrogel which allows unimpeded water movement around the sensor are provided. The surface coatings are compositions which are bi... | 10/08/2002 |
| 6461331 | Device and method for infusion of small molecule insulin mimetic materials A medication delivery device for delivering a small molecule insulin mimetic material to a body of an individual includes a housing, a reservoir and a controller. The housing contains a driving mechanism, and the reservoir is coupled to the driving mechan... | 10/08/2002 |
| 6413393 | Sensor including UV-absorbing polymer and method of manufacture A sensor is provided that includes at least one functional coating layer that includes a UV-absorbing polymer. Methods for making the inventive sensors are also provided.... | 07/02/2002 |
| 6362591 | Method and apparatus for detection of occlusions A method and apparatus for automatically detecting an occlusion or drive system failure in a medication infusion system is provided. The electrical current to an infusion pump is measured and compared against a baseline average current. If the current exc... | 03/26/2002 |
| 6340421 | Microelectrogravimetric method for plating a biosensor Disclosed is a method for microelectrogravimetrically depositing an electroactive species onto an electrode or a plurality of electrodes comprising dispensing a solution containing the electroactive species from a microdispenser to form a hanging drop of ... | 01/22/2002 |
| 6252032 | UV absorbing polymer An ultraviolet-absorbing polymer is formed from a reaction mixture including a diisocyanate, at least one selected from the group consisting of a diol, a diamine and mixtures thereof, and a polyfunctional UV-absorbing monomer.... | 06/26/2001 |
| 6110152 | Medication cartridge for an electronic pen-type injector, infusion pump, electronic delivery device, or the like, and method of making the same A cartridge for containing a fluid and for use with an electronic delivery device, includes a cartridge housing for holding the fluid, and information providing source. The information providing source is coupled to the cartridge housing to operatively co... | 08/29/2000 |
| 6093172 | Injector for a subcutaneous insertion set An injector is provided for automatic placement of a subcutaneous insertion set such as an infusion set or the like used for delivering a selected medication to a patient. The injector comprises a spring-loaded plunger having a head for receiving and supp... | 07/25/2000 |
| 6056718 | Medication infusion set An improved medication infusion set is provided of the type having a soft cannula for subcutaneous delivery of a selected medication to a patient. The infusion set comprises a cannula housing having a soft cannula protruding therefrom and a self-sealing s... | 05/02/2000 |
| 6011984 | Detection of biological molecules using chemical amplification and optical sensors Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where th... | 01/04/2000 |
| 6002954 | Detection of biological molecules using boronate-based chemical amplification and optical sensors Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an analyte transducer immobilized in a polymeric matrix, where th... | 12/14/1999 |
| 5957890 | Constant flow medication infusion pump A medication infusion pump is provided for substantially constant flow delivery of a selected medication from a medication chamber through a catheter to a patient. The medication infusion pump comprises a compact housing adapted for implantation into the ... | 09/28/1999 |
| 5954700 | Medication cartridge for an electronic pen-type injector, or the like, and method of making the same A cartridge for containing a fluid and for use with an electronic delivery device, includes a cartridge housing for holding the fluid, and information providing source. The information providing source is coupled to the cartridge housing to operatively co... | 09/21/1999 |
| 5954643 | Insertion set for a transcutaneous sensor An improved insertion set is provided for transcutaneous placement of a sensor such as a glucose sensor at a selected site within the body of a patient. The insertion set comprises a mounting base defining an upwardly open channel for receiving and suppor... | 09/21/1999 |
| 5951521 | Subcutaneous implantable sensor set having the capability to remove deliver fluids to an insertion site An implantable subcutaneous set for mounting onto a skin of a user and contacting a subcutaneous placement site beneath the skin includes a base, a cannula, an insertion device and an externally extending conduit. The base is used to secure the implantabl... | 09/14/1999 |
| 5882494 | Polyurethane/polyurea compositions containing silicone for biosensor membranes A homogenous polymer composition useful as a membrane for biosensors is disclosed. The polymer composition comprises the reaction products of a diisocyanate, a hydrophilic diol or diamine, and a silicone material. An aliphatic diol or diamine may also be ... | 03/16/1999 |
| 5851197 | Injector for a subcutaneous infusion set An injector is provided for automatic placement of a subcutaneous infusion set or the like used for delivering a selected medication to a patient. The injector comprises a spring-loaded plunger having a head for receiving and supporting an infusion set in... | 12/22/1998 |
| 5807315 | Methods and devices for the delivery of monomeric proteins Methods and devices for dissociating multimeric proteins and their delivery to patients, along with resultant compositions, are provided. A monomeric protein delivery device is also provided, comprising a supply of a multimeric protein 4, complex, compris... | 09/15/1998 |
| 5788678 | Indwelling catheter with stable enzyme coating An improved indwelling catheter adapted for long-term usage includes a stable enzyme coating to prevent occlusion of the catheter lumen. The enzyme coating includes a fibrinolytic and/or lipolytic enzyme incorporated in a catheter coating to resist or con... | 08/04/1998 |
| 5785681 | Flow rate controller for a medication infusion pump A flow rate controller is provided for regulating the flow rate of medication delivered to a patient by an implantable medication infusion pump of the constant flow type, to minimize or prevent flow rate increases attributable to fluctuations in ambient p... | 07/28/1998 |
| 5786439 | Hydrophilic, swellable coatings for biosensors Methods for reducing the electrode impedance of implantable biosensors by coating the surface of the biosensor with a uniform hydrogel which allows unimpeded water movement around the sensor are provided. The surface coatings are compositions which are bi... | 07/28/1998 |
| 5779665 | Transdermal introducer assembly A transdermal introducer assembly is provided for quick and easy transcutaneous placement of a medical tube on a patient with reduced patient discomfort. The introducer assembly comprises a medical tube segment defining a hollow lumen extending between a ... | 07/14/1998 |
| 5665065 | Medication infusion device with blood glucose data input A medication infusion device such as a programmable infusion pump includes data input regarding a selected patient parameter such as a current blood glucose reading. The infusion device includes a controller responsive to this data input to develop a medi... | 09/09/1997 |
| 5647853 | Rapid response occlusion detector for a medication infusion pump An improved occlusion detector is provided in a medication infusion pump to monitor medication delivery to a patient, and to provide an early alarm in the event of medication nondelivery. The detector comprises a force sensor and related control circuit f... | 07/15/1997 |
| 5637095 | Medication infusion pump with flexible drive plunger A medication infusion pump is provided for controlled delivery of medication to a patient, wherein the pump includes a space-efficient flexible drive plunger for advancing a piston within a medication-containing syringe or cartridge for administration of ... | 06/10/1997 |
| 5605152 | Optical glucose sensor An improved glucose sensor adapted for in vivo implantation includes one or more optical fiber optrodes mounted within a semipermeable probe housing designed for differential diffusion of glucose and oxygen. In a preferred form, an enzyme optrode comprise... | 02/25/1997 |
| 5586553 | Transcutaneous sensor insertion set An insertion set is provided for transcutaneous placement of a sensor such as a glucose sensor at a selected site within the body of a patient. The insertion set comprises a slotted insertion needle extending through a mounting base adapted for mounting o... | 12/24/1996 |
| 5584813 | Subcutaneous injection set A subcutaneous injection set is disclosed of the type having an insertion needle for quick and easy subcutaneous placement of a soft cannula through which medication can be delivered to a patient. In one preferred form, the subcutaneous injection set comp... | 12/17/1996 |
| 5568806 | Transcutaneous sensor insertion set An improved insertion set is provided for transcutaneous placement of a sensor such as a glucose sensor at a selected site within the body of a patient. The insertion set comprises an insertion needle extending through a mounting base adapted for mounting... | 10/29/1996 |
