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Assignee: Metaproteomics, LLC


Location: San Clemente, CA
No. of patents: 24

NumberTitleIssue Date
8168234Compositions that treat or inhibit pathological conditions associated with inflammatory response
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cell...
05/01/2012
8142819Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cell...
03/27/2012
8092846Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines
The invention provides compositions containing a fraction isolated or derived from hops and a methylxanthine. The invention additionally provides compositions containing a fraction derived from hops and a curcuminoid. The invention also provides methods of using suc...
01/10/2012
7919125Modulation of inflammation by hops fractions and derivatives
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandin selectively in target cells, and inhibit inflammatory response selectively in target cells...
04/05/2011
7914831Synergistic anti-inflammatory pharmaceutical compositions and related methods using curcuminoids or methylxanthines
The invention provides compositions containing a fraction isolated or derived from hops and a methylxanthine. The invention additionally provides compositions containing a fraction derived from hops and a curcuminoid. The invention also provides methods of using suc...
03/29/2011
7901713Inhibition of COX-2 and/or 5-LOX activity by fractions isolated or derived from hops
A natural formulation of compounds isolated or derived from hops which inhibit the activity of cyclooxygenase-2 (COX-2) and/or 5-lipoxygenase (5-LOX) is disclosed. The hops formulations may be administered to a mammal to treat or inhibit a pathological condition ass...
03/08/2011
7820206Modulation of inflammation by hops fractions and derivatives
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cell...
10/26/2010
7815944Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment of prevention of gastric toxicity
The invention provides hops (Humulis lupulus) extracts or derivatives thereof for use in treating a patient prophylactically and/or therapeutically for ulcerogenic-type disorders of the stomach and/or intestines. The ulcerogenic disorders can be of the type c...
10/19/2010
7811610Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment or prevention of gastric toxicity
The invention provides hops (Humulus lupulus) extracts or derivatives thereof for use in treating a patient prophylactically and/or therapeutically for ulcerogenic-type disorders of the stomach and/or intestines. The ulcerogenic disorders can be of the type c...
10/12/2010
7794757Modulation of inflammation by hops fractions and derivatives
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cell...
09/14/2010
7790205Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cell...
09/07/2010
7736677Xanthohumol and tetrahydro-isoalpha acid based protein kinase modulation cancer treatment
Compounds and methods for protein kinase modulation for cancer treatment are disclosed. The compounds and methods disclosed are based on xanthohumol or isoxantohumol, or tetrahydro-isoalpha acids commonly found in hops. ...
06/15/2010
7722903Modulation of inflammation by hops fractions and derivatives
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cell...
05/25/2010
7718198Treatment modalities for autoimmune diseases
Compositions of reduced isoalpha acids, vitamins and minerals are disclosed as well as methods of using the same for the treatment of autoimmune diseases. Additional combinations including other compounds are also contemplated. Synergistic properties and methods exp...
05/18/2010
7682636Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2
A novel formulation is provided that serves to inhibit the inflammatory response in animals. The formulation comprises, as a first component an effective amount of a curcuminoid species and an effective amount of a second component selected from the group consisting...
03/23/2010
7666449Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment or prevention of gastric toxicity
The invention provides hops (Humulus lupulus) extracts or derivatives thereof for use in treating a patient prophylactically and/or therapeutically for ulcerogenic-type disorders of the stomach and/or intestines. The ulcerogenic disorders can be of the type c...
02/23/2010
7431948Compositions that treat or inhibit pathological conditions associated with inflammatory response
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cell...
10/07/2008
7332185Complex mixtures exhibiting selective inhibition of cyclooxygenase-2
A novel formulation is provided that serves to specifically inhibit the COX-2 mediated inflammation response in animals. The formulation comprises comprising an effective amount of component I selected from the group consisting of alpha acids and beta acids and an e...
02/19/2008
7279185Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2
A novel formulation is provided that serves to inhibit the inflammatory response in animals. The formulation comprises, as a first component an effective amount of a curcuminoid species and an effective amount of a second component selected from the group consisting...
10/09/2007
7270835Compositions that treat or inhibit pathological conditions associated with inflammatory response
A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cell...
09/18/2007
7205151Complex mixtures exhibiting selective inhibition of cyclooxygenase-2
A novel formulation is provided that serves to specifically inhibit the COX-2 mediated inflammatory response in animals. The formulation comprises an effective amount of component I selected from the group consisting of alpha acids and beta acids and an effective am...
04/17/2007
7195785Complex mixtures exhibiting selective inhibition of cyclooxygenase-2
A novel formulation is provided that serves to specifically inhibit the COX-2 mediated inflammatory response in animals. The formulation comprises comprising an effective amount of component I selected from the group consisting of alpha acids and beta acids and an e...
03/27/2007
6979470Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2
Compositions comprising an effective amount of a curcuminoid species and an effective amount of a diterpene lactone species, a triterpene species or derivatives thereof that have a synergistic effect on specific inhibition of inducible COX-2 activity and have minima...
12/27/2005
6908630Combinations of sesquiterpene lactones and ditepene triepoxide lactones for synergistic inhibition of cyclooxygenase-2
A novel formulation is provided that serves to inhibit the inflammatory response in animals. The formulation comprises, as a first component an effective amount of a diterpene triepoxide lactone species and an effective amount of a second component of a sesquiterpen...
06/21/2005
 
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