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Assignee: Merial Limited


Location: Duluth, GA
No. of patents: 101

1      
NumberTitleIssue Date
8168200Vaccine against african horse sickness virus
The present invention provides vectors that contain and express in vivo the genes encoding VP2 and VP5 of African Horse Sickness Virus or an epitope thereof that elicits an immune response in a horse against African horse sickness virus, compositions comprising said...
05/01/2012
8163877Ligand gated ion channels from
The present invention relates in part to isolated nucleic acid molecules (polynucleotides) which encode Dermacentor variabilis ligand gated ion channel proteins. The present invention also relates to recombinant vectors and recombinant hosts which contain a D...
04/24/2012
8124642Pesticidal N-phenylpyrazole derivatives
The invention relates to 5-(substituted dithio- or dioxy-alkylamino)pyrazole derivatives of formula (I) or salts thereof: wherein the various symbols are as defined in the description, to processes for their preparation, to compositions thereof, and to their use for...
02/28/2012
8105776Breed-specific haplotypes for polled phenotypes in cattle
The presence of horns within commercial cattle populations increases the chances of injuries. The Polled (hornless) condition in cattle has existed since domestication, and it has been selected by breeders because of its economic importance and ease of management. A...
01/31/2012
80977321-arylpyrazoles and their use as pesticide
Disclosed are compounds of formula (I) or pesticidally acceptable salts thereof, wherein, for example, W is ═N—, ═CH—, ═CR7— or ═C(NR8R9)—, R7 is halogen, R8 and R9 are independently o...
01/17/2012
8097599Plasmid encoding feline BMP-7
The present invention relates to recombinant vectors expressing the BMP-7 polypeptide in host cells and to pharmaceutical compositions comprising such recombinant vectors. The invention also encompasses methods for prevention and/or treatment of both acute and chron...
01/17/2012
8097266Solvent systems for pour-on formulations for combating parasites
This invention relates to pharmaceutical and veterinary formulations providing enhanced solvency and stability for pharmaceutical and veterinary agents for administration to animals, especially ruminants. In addition, the invention relates to pour-on formulations fo...
01/17/2012
8088801Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): wherein R3, R4, R5, R6, R7, P, Q, V, W, X, Y, Z and a are as defined i...
01/03/2012
8067382Anthelmintic composition
The invention relates to a novel formulation having the advantage of including triclabendazole in solution. In addition a further anthelmintic may be included. The formulation is made by mixing the abamectin and benzyl alcohol and mixing this with triclabendazole an...
11/29/2011
8062645vaccine
The present invention relates to the field of vaccination against Salmonella in animals, particularly avian animals. The present invention also encompasses kits and uses of Salmonella immunogenic compositions or vaccines. The present invention further ...
11/22/2011
8008268Vaccines against vesicular stomatitis
The present invention relates to an immunogenic or vaccine composition to induce an immune response or protective immune response against vesicular stomatitis virus (VSV) in an animal susceptible to VSV. The composition may include a pharmaceutically or veterinarily...
08/30/2011
7998733Chimeric vectors
The present invention relates to chimeric vectors. More specifically, the invention relates to recombinant poxvirus vectors and viruses that are capable of expressing an alphaviral RNA replicon expressing a heterologous sequence of interest. ...
08/16/2011
7964621Thioamide compounds, method of making and method of using thereof
The present invention relates to novel thioamide derivatives of formula (I) and formula (Ia): wherein, R3, R4, R5, R6, R7, P, Q, T, V, W, X, Y, Z, a, m and n are as def...
06/21/2011
7943125Attenuated gram negative bacteria
Disclosed and claimed are a mutant of a gram negative bacterium, wherein said bacterium has at least one mutation in a nucleotide sequence which codes for a polypeptide having an identity which is equal or more than 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98%, or 99...
05/17/2011
7919522Compositions comprising C-13 alkoxyether macrolide compounds and phenylpyrazole compounds
Provided is a novel ivermectin derivative and compositions for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: (A) a pharmaceutically effective amount of a 1-N-phenylpyrazole compound; (B) a pharmac...
04/05/2011
7915010DNA molecules encoding L-glutamate-gated chloride channels from
The present invention relates in part to isolated nucleic acid molecules (polynucleotides) which encode Rhipicephalus sanguineus glutamate gated chloride channels. The present invention also relates to recombinant vectors and recombinant hosts which contain a...
03/29/2011
7910112Feline vaccines against avian influenza
The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a recombinant poxvirus vaccine or an inactivated vaccine. The invention also encompasses recombinant poxvirus vectors encoding and expressing avian influ...
03/22/2011
7906311Cotton rat lung cells for virus culture
A cotton rat cell line, uses of cotton rat cells for growing, propagating, or culturing organisms, pathogens or viruses, such as PRRSV, and uses of the resultant organisms, pathogens or viruses, are disclosed. ...
03/15/2011
7846428Articular cartilage gene therapy with recombinant vector encoding BMP-7
The present invention relates to recombinant vectors expressing the BMP-7 polypeptide in host cells and to pharmaceutical compositions comprising such recombinant vectors. The invention also encompasses methods for prevention and/or treatment of osteoarthritis in ma...
12/07/2010
7879897Pesticidal 5-substituted-oxyalkylamino-1-arylpyrazole derivatives
The invention relates to 5-sub-stituted-oxyalkylaminopyrazole derivatives of the formula or salts thereof wherein the various symbols are as defined in the description, to processes for their preparation, to compositions th...
02/01/2011
78720381-phenyl and 1-pyridylpyrazole derivatives and their use as pesticides
The invention relates to 1-(2,4,6-trisubstituted-phenyl)-5-amino-4-substituted-pyrazole derivatives of formula (I) or salts thereof wherein the various symbols are as defined in the description, to processes for their preparation, to compositions thereof, and to the...
01/18/2011
7862821Recombinant vaccine against bluetongue virus
The present invention relates to an immunogenic or vaccine composition to induce an immune response or protective immune response against Orbiviruses, more specifically bluetongue virus (BTV) in an animal susceptible to BTV infection. The composition may incl...
01/04/2011
7850978Vaccine against feline calicivirus
The present invention relates to improved methods and immunogenic and/or vaccine compositions for providing an immune response to feline calicivirus, including hypervirulent strains of feline calicivirus. ...
12/14/2010
7850665Multiple fluid delivery device for poultry
The present invention provides an injection delivery system for the injection delivery of at least two fluid doses to a small bird by penetrating the skin of the recipient bird with at least one injection needle. The present injection delivery system comprises an in...
12/14/2010
78340035-aminopyrazole derivatives as pesticidal compounds
The invention relates to 5-Aminopyrazole derivatives of formula (I) or salts thereof, a process for their preparation, to compositions thereof and to their use for the control of pests, including arthropods and helminths. ...
11/16/2010
7829323Mixing devices for chemical lysis of cells
The invention relates to flow-through devices for mixing fluids and uses thereof for mixing and for lysing cells to release biological compounds of interest. The invention particularly encompasses flow-through methods for mixing and chemical methods for the isolatio...
11/09/2010
7820709N-phenylpyrazole derivatives as pesticides
The invention relates to polar 5-aminopyrazole carbamate derivatives of formula (I) or salts thereof: (I), wherein the various symbols are as defined in the description, to processes for their preparation, to compositions thereof, and to their use for the control of...
10/26/2010
7803612Nipah virus vaccines
The present invention relates to recombinant anti-Nipah virus vaccines and the administration of such vaccines to animals, advantageously pigs. Advantageously, the anti-Nipah virus vaccine may comprise a recombinant avipox virus containing a Nipah virus glycoprotein...
09/28/2010
7794736Canine vaccine
The present invention provides vectors that contain and express in vivo Leishmania KMP11 or an epitope thereof that elicits an immune response in a dog against Leishmania, compositions comprising said vectors, methods of vaccination against Leishman...
09/14/2010
7772205Gene therapy for renal failure
The present invention relates to recombinant vectors expressing the BMP-7 polypeptide in host cells and to pharmaceutical compositions comprising such recombinant vectors. The invention also encompasses methods for prevention and/or treatment of both acute and chron...
08/10/2010
7771995Plasmid encoding human BMP-7
The present invention relates to recombinant vectors expressing the BMP-7 polypeptide in host cells and to pharmaceutical compositions comprising such recombinant vectors. The invention also encompasses methods for prevention and/or treatment of both acute and chron...
08/10/2010
7741437polypeptides, polypeptides and methods of use
Substantially purified salivary P. ariasi and P. perniciosus polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the P. ariasi and P. perniciosus polynucleotides are also disclosed...
06/22/2010
7732416Avermectins substituted in the 4″-position having pesticidal properties
What is described are a compound of the formula in which R1 is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alk...
06/08/2010
7718390Toxoplasma gondii cylclic GMP dependent protein kinase G as a chemotherapeutic target for antiprotozoal agents
Protozoal cyclic GMP dependent protein kinases have been isolated and cloned. These enzymes may be used in screening assays to identify potential antiprotozoal agents. ...
05/18/2010
7704961Avermectins and avermectin monosacharides substituted in the 4′-and 4″ position having pesticidal properties
Described is a compound of the formula (I) wherein the bond between carbon atoms 22 and 23 is a single or double bond; m is 0 or 1; R1, is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; and...
04/27/2010
7700639Chemical compounds, process for their preparation and use thereof
Disclosed are compounds of formula (I) or pesticidally acceptable salts thereof wherein, for example, W is ═CR8— or ═C(NR9R10)—, R8 is halogen, R9 and R10 are independently of one another hydr...
04/20/2010
7691368Vaccine formulations
The present invention relates to oil-in-water emulsions, their use as adjuvants, and pharmaceutical, immunologic, or vaccine compositions that may comprise the same. In one embodiment, the oil-in-water (O/W) emulsion may comprise an aqueous solution containing an im...
04/06/2010
76787971-phenyl-3-piperazine-pyrazoles and pesticidal compositions of matter thereof
The invention relates to 5-diazacycloalkylpyrazole derivatives of the formula (I) or salts thereof a process for their preparation, to compositions thereof and to their use for the control of pests, including arthropods and helminths ...
03/16/2010
7678773Salts of avermectins substituted in the 4″-position and having pesticidal properties
A compound of formula wherein X− is an anion; n is 1, 2, 3 or 4; R1 is C1-C12alkyl, C3-C8cycloalkyl; or C2
03/16/2010
7678740Avermectin and avermectin monosaccharide derivatives substituted in the 4″-or 4′-position having pesticidal properties
What is described are a compound of the formula (I) Wherein U is —N(R2)OR3 or —N+(O−)═C(RE)RZ); n is 0 or 1; X—Y is —CH═CH— or —CH2—CH2—; R1 is C...
03/16/2010
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