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Assignee: Mercator Genetics, Inc.


Location: MenloPark, CA
No. of patents: 6

NumberTitleIssue Date
6025130Hereditary hemochromatosis gene
The invention relates generally to the gene, and mutations thereto, that are responsible for the disease hereditary hemochromatosis (HH). More particularly, the invention relates to the identification, isolation, and cloning of the DNA sequence correspond...
02/15/2000
5872237Megabase transcript map: novel sequences and antibodies thereto
A fine structure map of the 1 megabase region surrounding the candidate HH gene is provided, along with 250 KB of DNA sequence and 8 loci corresponding to candidate genes within the 1 megabase region. These loci are useful as genetic markers for further m...
02/16/1999
5753438Method to diagnose hereditary hemochromatosis
New genetic markers for the presence of a mutation in the common hereditary hemochromatosis (HH) gene are disclosed. The multiplicity of markers permits definition of genotypes characteristic of carriers and homozygotes containing this mutation in their g...
05/19/1998
5712098Hereditary hemochromatosis diagnostic markers and diagnostic methods
A single base-pair polymorphism involving a mutation from Guanine (G), in individuals unaffected by the hereditary hemochromatosis (HH) gene defect, to Adeninc (A), in individuals affected by the HH gene defect is disclosed. The presence or absence of the...
01/27/1998
5705343Method to diagnose hereditary hemochromatosis
New genetic markers for the presence of a mutation in the common hereditary hemochromatosis (HH) gene are disclosed. The multiplicity of markers permits definition of genotypes characteristic of carriers and homozygotes containing this mutation in their g...
01/06/1998
5670321Efficient method to conduct large-scale genome sequencing
An efficient method for sequencing large fragments of DNA is described. A subclone path through the fragment is first identified; the collection of subclones that define this path is then sequenced using transposon-mediated direct sequencing techniques to...
09/23/1997
 
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